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phren0logy · 6 months ago
I’m a psychiatrist, so if you consider that a significant bias I’m disclosing it.

While there has been a level of diagnostic expansion that I don’t think is helpful, it’s also important to consider:

What’s the psychiatric equivalent of a sprained ankle?

Does something have to be catastrophic to warrant a diagnosis?

bjornsing · 6 months ago
I think it will be hard to expand psychiatry to that level while keeping it professional. The fundamental issue is that people ascribe personality flaws to others instinctually and also have strong feelings around being subjected to such treatment, in a way that they don’t have around sprained ankles. In everyday life it’s called badmouthing or trash-talking. It’s a part of human nature.
ssivark · 6 months ago
Doesn't that presume that human psychology (cognitive functioning) is uniform at a level that would obviate the need even for personalities and styles?

Our physiological system does have that uniformity across the population but our psychological system does not seem to. Isn't it then misguided to try characterizing small deviations when we don't even have a uniform "background" to subtract?

Retric · 6 months ago
I think you’re overlooking the difference between diversity and changes to an individual.

Some people can’t get stranded ankles because they don’t have legs, so you don’t necessarily need a universal baseline across all of humanity when diagnosing conditions. Someone who is still within normal ranges but significantly doing worse than they where can quite reasonably seek treatment.

suggestion · 6 months ago
There isn't one because a sprained ankle is a binary diagnosis.

One of the biggest problems with psychiatry is that every diagnosis is a spectrum, and over time it's become more and more obvious that the boundaries for what is considered "neurotypical" are way too narrow.

Depression being a chemical imbalance was a complete lie to sell more medication, and how prolific this type of occurrence is within the industry is not hard to see.

At the very least, a plurality of phycological diagnoses are manifestations of physical behavior: diet, exercise, exposure to sunlight, etc

We're so overprescribed on medications to try to feel a certain way within far too narrow of a spectrum.

Why do you presume that there has to be an equivalent to a sprained ankle? Maybe the answer to your question is yes, only the catastrophic is worth addressing.

https://journals.plos.org/plosmedicine/article?id=10.1371/jo...

KPGv2 · 6 months ago
> only the catastrophic is worth addressing

This is a very privileged view of the mind. I have ADHD (and autism). But I also have a quite high IQ, if one cares about such things. I'm pretty successful, professionally.

But it took until around 40yo to get the ADHD diagnosis and get a prescription for medication that has been life-altering. Was I suffering from catastrophic failures? Absolutely not: married, have kids, in the 1%, etc.

But have the meds had an incredibly positive influence on my life? Hell yes. I can do things that everyone else acted like was normal, but I straight up couldn't do it before. Housework is a prime example. It was like torture. Sitting around waiting for people to finish their sentences because they're "talking as slow as molasses" made for often unenjoyable social experiences.

But with the meds, this stuff is either tolerable or fun. My life is significantly better thanks to medical interventions. Instead of my wife blowing up because I didn't do something like mop the kitchen floor, I actually get it done (without meds I straight up cannot hold that kind of task in my mind if I'm not in the room looking at the mess; I will flit between ten other things in a different part of the house, then walk through the kitchen to get into my car to pick up the kids, see the kitchen, and think "ah, fuck me")

I'm happy that you're neurotypical and have a great life, but that's not true for a lot of us, and the idea that "only catastrophic mental issues should be dealt with by professionals" is you just telling on yourself and your ignorances.

ben_sisko · 6 months ago
“Chemical imbalance” lol.

You have inadvertently outed yourself as not having a clue by your reply. It’s nothing personal but you just clearly don’t have a clue and/or don’t have skin in the game.

It’s fine. I don’t know anything about professional juggling because I have zero skin in that game.

Paging Dr. Brochacho: fMRI and brain networks have been around for a while!

rrsp · 6 months ago
Why does psychiatry need to have an ‘equivalent’ of a sprained ankle?

Most people recognise a sprained ankle, at least mild ones, as a self limiting illness. An issue with psychiatric diagnoses is that they are often not taken to be self limiting and often become a large part of a patients self image. While sometimes this can be helpful and help inform treatment it can also be harmful and I have seen this harm first hand in patients I see.

gmokki · 6 months ago
If there is no sprained ankle diagnostics and doctors just tell you to ignore not being well: just jump and run around as normal there is nothing seriously wrong.

And doctors only react when you can no longer use your legs for a year, otherwise they must be amputated.

Or would you rather have an earlier disgnostic with instructions to reduce extreme loads and try to take it easy. Let's check again in a week.

jychang · 6 months ago
That sounds like not the psychologist’s fault. Don’t blame the doctor if their patient makes a sprained ankle their identity.

If someone smokes a lot of cigarettes and gets lung cancer, we don’t blame the doctor for the lung cancer. This shit is the patient’s responsibility.

Deleted Comment

pyuser583 · 6 months ago
> What’s the psychiatric equivalent of a sprained ankle?

Not sleeping a night.

Retric · 6 months ago
> What’s the psychiatric equivalent of a sprained ankle?

A concussion? Obviously it’s not considered a psychiatric condition but concussions check a lot of the right boxes abstractly.

sedivy94 · 6 months ago
What’s the right word to differentiate this from a psychiatric diagnosis? Neurological?
vjulian · 6 months ago
What counts as a “disorder” is often not based on empirical evidence but on what is determined as undesirable, maladaptive, or outside the social norm…by Americans. The DSM in many ways represents the worst of so-called social science.
connicpu · 6 months ago
But conceptually in the DSM most disorders are defined by whether they cause hardship in the patient's life. Whether that means some disorders would not have to be considered disorders in an ideal society is irrelevant for this context, because people need help navigating the society we have.
noosphr · 6 months ago
Remember that in the US slaves wanting freedom was a mental disorder that made it past peer review: https://en.wikipedia.org/wiki/Drapetomania
cyanydeez · 6 months ago
unfortunately, what seems to be driving modern disorder diagnosis is what gets issurance to pay. That's why autism is now a spectrum.
reorder9695 · 6 months ago
How else would you do it? Unlike an e.g. viral infection there is no positive test you can look at. Generally a disorder is considered something that significantly impacts someone's life, getting in the way of things like working, social life, life enjoyment. I don't think you can be totally objective about this, and you get into things like if i.e. autism is mild is it a disorder? It's pretty clear to me it should be considered as such after a certain level of severity, but maybe it shouldn't always be if it has minimal impact on the person
aleph_minus_one · 6 months ago
> Generally a disorder is considered something that significantly impacts someone's life, getting in the way of things like working, social life, life enjoyment.

With the same argument, we could arguue that working and social life are getting in the way how I am, thus working and social life should be considered disorders.

brooke2k · 6 months ago
A "disorder" is just a collection of symptoms that have been empirically shown to benefit from certain treatments. If someone doesn't think they have those symptoms then they can just not seek a diagnosis or treatment. Nobody is forcing a diagnosis on somebody who doesn't want it.
bjornsing · 6 months ago
If you look into the history of psychiatry I think you’ll find quite a lot of examples when diagnosis and treatment was forced on people who didn’t want it. It’s not hard to find contemporary such examples either.
s5300 · 6 months ago
>> Nobody is forcing a diagnosis on somebody who doesn't want it.

Ahh, you sweet summer child

Tell that to all multiple sclerosis patients that were tortured by psych departments of hospitals before (and after) the MRI machine was created.

Tell that to sleep apnea patients (especially the women, especially especially the younger thinner women in whom they say “it cannot happen to”) that are given a psych diagnoses for seeking treatment for symptoms before sleep disordered breathing issues are ever even brought into question.

The main problem is that DSM diagnoses are indeed forced on people. Usually highly incorrectly, too.

gruez · 6 months ago
>What counts as a “disorder” is often not based on empirical evidence but on what is determined as undesirable, maladaptive, or outside the social norm

What's the alternative then? What would "empirically" determining what a "disorder" is look like?

>…by Americans

Most of the world outside of the US uses the ICD, not the DSM.

NikolaNovak · 6 months ago
Agreeing that social science is harder than most, I see these definitions as “circle around a set of presentations / symptoms / behaviours “. As somebody who has several circles around them, it doesn’t bother me overly. Historical enforced procedures / incarcerations did, but I understand value of “common language”. In a wildly different area that may or may not resonate with HN, I find similar value in PMP or ITIL - it’s not the One True Way, it is not necessarily a permanent scientific best approach… but it does give people of today a way to communicate with each other across domains, companies, cultures and experiences .
epgui · 6 months ago
> The DSM in many ways represents the worst of so-called social science.

No. You need to read the thing.

The DSM only aims to be a tool to help standardize communication of often nebulous and otherwise ill-defined entities. It says so in the introductory pages.

People shouldn’t treat it like a biology textbook, it’s a self-described ontology at most.

sundarurfriend · 6 months ago
But people do. Psychology courses do, with a similar "tool to help standardize communication" line recited robotically and then practically ignored. Most practicing psychologists do as well, to only a somewhat lesser degree.

You cannot have an authoritative textbook proscribing definitions, and then expect people to treat them as just "a self-described ontology" with all the nuances and caveats around that just because it says so somewhere in the introduction. Psychology of all fields should know that.

autoexec · 6 months ago
> What counts as a “disorder” is often not based on empirical evidence but on what is determined as undesirable, maladaptive, or outside the social norm…by Americans.

I've seen that used before to dismiss the severity of conditions like autism and especially ADHD. It's often coming from a well-meaning place, and sometimes it's just a comforting story people tell themselves in order to not feel as deficient ("The problem isn't me, it's the system!").

It's also absolutely true that the demands society places on all of us are unnatural and often excessive, but the fact is that even absent all external expectations some people with mental illness will be unable to accomplish what they themselves want and should be able to accomplish.

Even the most utopian, accepting, accommodating society it wouldn't be enough to make up for some people's inability to function.

I feel the same about a lot of the "super power" talk when it comes to mental illness. There are advantages and disadvantages to just about anything, but on the whole conditions like ADHD or autism tend to do way more harm than good.

mcslambley · 6 months ago
“Empirical evidence” and “what is determined as undesirable, maladaptive, or outside the social norm” are not mutually exclusive.
birn559 · 6 months ago
My inability of being in nature without a feeling of being tortured comes from my brain not working correctly and it's not "undesired behavior". Luckily, my ADHD meds are able to fix that.
riazrizvi · 6 months ago
Without a clear and agreed behavioral model, I don’t see how disorders can be properly defined.
ben_sisko · 6 months ago
The exercise and food science people are the worst of social science buddy. Or just “social” something, because it’s not science. “Science-based” always makes me laugh.

The DSM only matters if somebody is actively seeking treatment for something that they have a problem with in their own situation. So what’s in there is totally irrelevant for the public at large. It’s only if somebody shows up and says there’s something going on that they don’t like. It’s really just billing codes, man. The reality is far different anyway, and it just gets distilled down to these primitive codes.

naveensundar · 6 months ago
I think this is not a valid criticism.

By this criteria, you can then say many other non-psych conditions are not disorders.

What classifies as a disorder other than making life worse for someone?

There is no universal book given by a holy entity that we can read to classify something as normal or a disorder.

Why do we have arbitrary cutoffs for cholesterol, blood sugar, blood pressure, etc?

readthenotes1 · 6 months ago
I wonder how much of the DSM is based on loose correlations, non-replicated or fraudulent research.

I get the feeling that we understand how our brains work about as well as we understand how well mitochondria work - - and I see reports of new findings on mitochondria fairly regularly...

brooke2k · 6 months ago
The DSM isn't about understanding how the brain works, it's about correlating sets of symptoms to treatments. If your issues are characterized by this broad set of symptoms, then likely you'll benefit from these sorts of treatments, and etc. We don't have a good understanding of how the brain works, but we're pretty confident that people with schizophrenia often benefit from antipsychotic medications.
hx8 · 6 months ago
In some ways the financial conflicts of interest make sense, because the people that best understand a set of symptoms probably also are the ones in the best position to create new treatments. Being undisclosed makes it feel way more scummy than it might actually be.
yoshuaw · 6 months ago
It's hard to tell honestly. I studied psychology for two years in uni, and I dropped out rather disillusioned about the field. Some of my least favorite aspects included:

  - Acknowledgement by our professors that P-hacking (pruning datasets to get the desired results) was not just common, but rampant

  - One of our classes being thrown in limbo for several months after we found out that a bunch of foundational research underpinning it was entirely made up (See: Diederik Stapel).

  - Experiencing first-hand just how unreproducible most research in our faculty was (SPSS was the norm, R was the exception, Python was unused).

  - Learning that most psychology research is conducted on white psychology students in their early/mid-twenties in the EU and US. But the findings are broadly generalized across populations and cultures.

  - Learning that the DSM-IV classified homosexuality as a mental disorder. Though the DSM-V has since dropped this. 
The DSM-V is still incredibly hostile towards trans people through a game of internal power politics and cherry-picked research. It's really bad honestly.

Though I do generally hold psychologists in high regard (therapy is good), I'm not particularly impressed by psychology as a science. And in turn don't necessarily trust the DSM all that much.

fsiefken · 6 months ago
> Experiencing first-hand just how unreproducible most research in our faculty was (SPSS was the norm, R was the exception, Python was unused).

How did you experience this? Did you fail to reproduce the same results when doing the research again while using R? This is how I interpret your statement, but I think it's not what you mean.

If SPSS was the norm, R or SciPy shouldn't have made a difference in reproducibility as the statistics should be more or less the same. I did social science with SPSS fine; T-Tests, MANOVA, Cronbach's alpha, Kruskall-Wallis, it's all in there. It seems you suggest that using SPSS inherently makes for bad and irreproducible science, it's similar to saying using Word instead of an open source package like LaTeX makes research unreproducible even if the data, methodology and statistics are openly accessible. This is not the case. What i mean is that while I agree there can be friction between using Word and SPSS and Open Science and FAIR principles because of the proprietary formats, this isn't inherently a problem as people can use the dataset (csv or sqlite) and do the mentioned statistical tests outlined in the published pdf (or even an imported docx) in any statistical language.

https://www.go-fair.org/fair-principles/

For anyone looking for an easy to use alternative to R, Jamovi is a capable and easy to use open source alternative to SPSS and RStudio. https://medium.com/@Frank.M.LoSchiavo/jamovi-a-free-alternat...

aeve890 · 6 months ago
>One of our classes being thrown in limbo for several months after we found out that a bunch of foundational research underpinning it was entirely made up (See: Diederik Stapel).

That's mild. In one of Chile's largest and most prestigious universities, Jodorowsky "psychomagic" is teached as a real therapeutic approach.

JBits · 6 months ago
At least you're working with Rust now.

As someone with zero knowledge of psychology, I'm biased against it. Partly because of my vague impression that psychology tries to fit people to models, rather than viewing models as limited approximations.

For a while I've thought it would be nice to know what results the field of psychology actually has that are trusted. Was there anything at all in the taught content which you liked? I didn't realise the DSM-V was that bad. If research on trans people can be cherry-picked, then does that mean that some reliable research exists?

dehrmann · 6 months ago
> One of our classes being thrown in limbo for several months after we found out that a bunch of foundational research underpinning it was entirely made up (See: Diederik Stapel).

I wonder if you can sue for fraud over this. The researcher knowingly deceived academia, and it's foreseeable that students would then pay to study the the false research.

fsckboy · 6 months ago
>P-hacking rampant

give us your best academic hypothesis as to why p-hacking is rampant: I'll bet it will sound like psych analysis

epgui · 6 months ago
This is the wrong question… The DSM is just an ontology that aims to standardize communication of otherwise ill-defined or nebulous clinical entities. It provides language for medical professionals of various backgrounds to understand each other across cultures. That’s all it is.
supportengineer · 6 months ago
It's a sorting hat
cwmoore · 6 months ago
Kind of like…labeling people by race? Surely there are misalignments.
IFC_LLC · 6 months ago
I took the liberty of indulging in some reading.

I must admit, it feels a bit strange. The truth is that I learned my first steps in programming by working through large, formidable books. In fact, my very first programming book was Assembly Language for Intel-Based Computers by Kip Irvine. After that, I read even larger books, many of them multiple times.

I have always been fond of reading well-written books by knowledgeable professionals. After reading such works, you come away with real understanding, greater clarity, and often new creativity. Books are valuable, and I have always respected a good one.

Yet the DSM-5-TR is quite the opposite. The Preface clearly states that the work is intended for everyone:

“The information is of value to all professionals associated with various aspects of mental health care, including psychiatrists, other physicians, psychologists, social workers, nurses, counselors, forensic and legal specialists, occupational and rehabilitation therapists, and other health professionals.”

I happen to be a social worker, and I have read a lot of books. I know how to study. I carefully looked up any words I might have misunderstood and used the dictionary freely.

But despite all my efforts, I often failed to make sense of what I was reading. One would expect a theory followed by a conclusion, or an observation leading to a conclusion, or a theorem that is then proven. Unfortunately, that structure is missing here.

A typical DSM entry begins with a statement presented as fact, only to be followed by other statements that seem to contradict it.

Take, for example:

“The prevalence of disinhibited social engagement disorder is unknown. Nevertheless, the disorder appears to be rare, occurring in a minority of children, even those who have experienced severe early deprivation. In low-income community populations in the United Kingdom, the prevalence is up to 2%.”

This kind of contradictory phrasing is standard in the DSM.

Again, the DSM is publicly available, and anyone can read it here: https://www.ifeet.org/files/DSM-5-TR.pdf

I would have expected more precision from a scientific book.

naveensundar · 6 months ago
Logically, your example is not contradictory.

  1. We don't know actual prevalence
  2. But believe it is low
  3. Upper bound in some community is 2%
It is not at all contradictory.

NoahZuniga · 6 months ago
> This kind of contradictory phrasing is standard in the DSM.

I'm not sure I see what's contradictory in your example. Could you elaborate?

SketchySeaBeast · 6 months ago
The brain is certainly difficult to study, but does it not stand to reason that there should be a collection of the current understanding of how to treat things when they go wrong? No one is calling the DSM V the final, definitive, work, there's a reason it's numbered.
suggestion · 6 months ago
Nearly all of it, because that's the case for the overwhelming majority of the social sciences.

When you do not have an objective metric to measure, prove, or hypothesize (as in physics, chemistry, etc), you're basically doing statistics on whatever arbitrary populations and bounds you choose with immeasurable confounders. That's why the replication crisis and p hacking are intrinsic properties of the social sciences

richgroot · 6 months ago
So these folks are implying that the rework of the DSM-4 into DSM-5 was tainted in some way by association of the authors with pharma or other industries? Do I understand that correctly?

Is there an example that anyone has pointed to where DSM-5 could have been written differently, to the detriment of a commercial enterprise? (What little I've read in the DSM-5 is enough to leave one with glazed eyes.)

worik · 6 months ago
> So these folks are implying that the rework of the DSM-4 into DSM-5 was tainted in some way by association of the authors with pharma or other industries?

Yes

This has been known to economists for a long time

Medicine generally has had its progress (as a general good) held back by misaligned incentives for a long time

See "neglected tropical diseases"

As true in psychiatry as anything else

gruez · 6 months ago
>See "neglected tropical diseases"

That seems totally different than what the OP is trying to imply, which seems to be that people who worked on the DSM added illnesses to it so they or their backers could financially benefit. If it's just a matter of "illness that can be better monetized have more financial backers, and therefore they get more attention", that seems... fine? In an ideal world I'd want malaria and whatever first world ailment (obesity?) to be treated equally on some objective factor like QALYs or whatever, but I don't see anything intrinsically wrong with private companies preferentially funding research that they stand to benefit from.

allemagne · 6 months ago
The OP did ask that first question, but to me it read as being more rhetorical so that we could maybe get specific answers about what in the DSM-5 would have been written differently otherwise.
nullc · 6 months ago
> As true in psychiatry as anything else

Wouldn't we expect it to be more true the fewer objective measures there are? Like if a treatment is supposed to improve blood sugar, and we can measure blood sugar cheaply in real time... we should expect misaligned incentives to have diminished effect compared to something where there is less ability to objectively measure, such as pretty much anything in psychiatry.

dalemhurley · 6 months ago
Next there will be a paper on the accountants that set accounting standards have a financial interest in accounting.
potato3732842 · 6 months ago
I'm pretty sure we have tablets from Babylon wherein homeowners are complaining that the building code was ghost written by the mud brick lobbyists.
jasonfarnon · 6 months ago
" The FASB was conceived as a full-time body to insure that Board member deliberations encourage broad participation, objectively consider all stakeholder views, and are not influenced or directed by political/private interests "
ben_sisko · 6 months ago
The DSM diagnostic categories are glorified billing codes that everybody (who actually has real ground contact with mental health care for real for real) recognizes as primitive, Stone Age relics.

In five or ten years, these categories will feel like missteps of the past (akin to calling all mental illness “hysteria”).

dostick · 6 months ago
Easy to check by looking at records how DSM was worked on. Evidence of how financial conflicts translated into diagnostic expansion:

The Bereavement Exclusion Smoking Gun 100% of the DSM-IV mood disorders work group had financial ties to pharmaceutical companies Mad In America . This same group eliminated the bereavement exclusion in DSM-5, allowing normal grief to be diagnosed as major depression after just two weeks. Kenneth Kendler, speaking for the group, explicitly argued “Either the grief exclusion criterion needs to be eliminated or extended so that no depression that arises in the setting of adversity would be diagnosable” Mad In America - essentially arguing that context should be irrelevant to psychiatric diagnosis. This change was “perhaps the most controversial change from DSM-IV to DSM-5” PubMed Central and critics argued it would “result in an increasing number of persons with normal grief to be inappropriately diagnosed with MDD after only two weeks of depressive symptoms” American Academy of Family Physicians and lead to unnecessary antidepressant prescribing.

The ADHD Expansion: DSM-5 systematically lowered ADHD diagnostic thresholds: - Reduced symptom threshold from 6 to 5 symptoms for adults/adolescents over 17 PubMed Central Neurodivergent Insights - Increased age of onset requirement from 7 to 12 years old Neurodivergent Insights - Lowered impairment criteria - now only need to “reduce quality of functioning” rather than be “clinically significant” PubMed Central Critics specifically identified ADHD expansion as worsening the “false positive problem” by “expanding diagnosis to adults before addressing its reliability in children”

moi2388 · 6 months ago
The DSM is a bunch of nonsense. As long as they don’t provide physical mechanisms for disorders, it’s worthless. It clusters symptoms without knowing the underlying causes.

It’s like going to the doctor with a runny nose, who the claims it’s influenza, due to the runny nose, without testing for Covid.

LeoWattenberg · 6 months ago
It clusters symptoms "without underlying cause" because we don't know the underlying cause. If we wanted to go for a fully "physical mechanism" approach to mental health, we could just end any treatment attempts and say "come back in a few decades or perhaps centuries".

But we do know that certain symptoms tend to show up in clusters, and that patients in certain clusters tend to respond to certain drugs with an above-placebo level of effectiveness.

The same is true for a runny nose: It can be caused by any number of viruses (there is no such a thing as "the" influenza virus or "the" common cold virus), or allergies, or irritants like pepper spray, or a problem with the body's ability to regulate itself, or something else entirely – but going through the effort to test for every virus, allergen, irritant, and whatnot is wasteful, if all the patient needs at that moment is some nasal spray to breathe properly again. Incidentally, a runny nose is (or perhaps: was) not a common symptom of Covid, so unless other symptoms more indicative of it show, there may not a good reason to test for it, or prescribe medication specific to it.

If more symptoms accumulate over time, or the symptoms don't go away, you then probably can go back to your doctor, will get a different diagnosis and possibly a different prescription. The same is (or at least: should be) true for mental issues, where you might switch treatment over and over until something is found which actually helps your symptoms. Is this a flawed process? Frustrating? Absolutely. But is it "worthless"? I don't think so.

dns_snek · 6 months ago
> it’s worthless

Hundreds of millions of people whose lives have been saved or improved thanks to broader recognition and treatment of their disorder would disagree.

ddq · 6 months ago
Can you provide evidence-based numbers of how many people's lives have been saved or improved vs how many have been ruined or ended in part due to the guidelines DSM? Or what the outcomes would have been had psychiatry not continued to rely on it as the gold standard? Without a comparison, a vague, unsubstantiated claim such as that is worthless.
ndr · 6 months ago
While I agree that DSM is likely a bunch of nonsense:

> As long as they don’t provide physical mechanisms for disorders, it’s worthless

This reasoning will dismiss too many things.

We don't know the physics of almost anything, it's all progressive levels of approximation.

For the longest time we knew nothing about the physical mechanisms of anesthetics, or how a plane wing works.

Science doesn't need the mechanism. It needs predictive power. Observations, hypotheses, tests and thesis.

richgroot · 6 months ago
Yep. Quantum mechanics, for example, works, even though we don't understand the underlying thing that the model describes.
tsoukase · 6 months ago
You are wrong. Medicine does not need physical mechanisms for any diagnosis or therapy. It is preferable but not obligatory. A mere grouping of a symptom cluster forms a diagnosis as well as a therapeutic target.
moi2388 · 6 months ago
Then I sure hope somebody with HIV never goes to the doctor with a runny nose, since I’m pretty sure staying in bed a week doesn’t solve the underlying issue.
w3ll_w3ll_w3ll · 6 months ago
Ahahah I know what you did here.