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jvanderbot · 5 years ago
Theanine has been shown to have a noticeable relaxation without sedative effect, and a minor decrease in anxiety, within minutes of ingestion.

Yes, there are problems with all studies, and it sure is fun to pile on, but a cursory search of examine.com confirms my own experience and that of amateur noot-ers: Theanine takes the edge off caffeine and helps focus. Caffeine+Theanine is the third highest recommended home treatment for focus (behind exercise and sleep) on r/nootropics for whatever that's worth.

You can find other studies here: https://examine.com/supplements/theanine/

I take it semi-regularly during times I'm over-consuming caffeine, but find that I come to resent its absence when I stop taking it.

reader_mode · 5 years ago
>Caffeine+Theanine is the third highest recommended home treatment for focus (behind exercise and sleep) on r/nootropics for whatever that's worth.

I'm surprised modafinil isn't no. 1

I don't use it regularly to avoid developing a tolerance, but that thing has a profound impact on the ability to focus and power through, nothing else I've tried comes even close. I guess speed/amphetamine but that gets me euphoric and I notice elevated heart rate, I don't feel any different on modafinil other than focused and tiredness being blocked.

LeifCarrotson · 5 years ago
I'm sure it's primarily because caffeine and theanine are culturally accepted and available cheaply over-the-counter. Modafinil is prescription-only (at least in the US), and speed/amphetamines are likewise illegal.

Instead of asking your doctor for psychoactive drugs or delving through the dark corners of the internet or dark corners of downtown alleys, you can get caffeine at Walgreens or Starbucks.

likeabbas · 5 years ago
Interesting. My anecdotal experience with modafinil is that I get extreme anxiety and elevated heart rate without any additional focus benefits. In fact, it detriments my ability to focus.

Adderall on the other hand, while stimulating and euphoric, gets the job done. But it works so well that I have trouble focusing without it now. I’ve tried tapering off multiple times but always go back to it when my work quality suffers and I’m not contributing to tasks that my team needs done.

espresso_enigma · 5 years ago
re. Modafinil, I heard it mentioned by a reputable programmer on twitter and decided to try it. I used it regularly for several years, and it was extremely useful in helping with focus and staying on task. I feel like it helped me in a breakthrough phase of my career. The problem I found was that I could only tolerate it 2-3 times per week over the long term. Any more than that, and the edgy/anxious/irritable side effects would build up to intolerable levels. Not to mention I was buying from questionable sources online, figuring it would be too difficult to talk a doctor into prescribing me some.

Eventually though I worried about the quality of the batched I was getting online and stopped taking it altogether. But I still really struggled with focus on a daily basis and started to wonder if what I was really doing was self medicating for undiagnosed ADHD. Thinking back on my life it did sort of fit. Though I am a "successful" developer and I'm doing fairly well at life, it has always felt like I had to struggle and fight a lot more than the average person just go get through the day and stay on task. So I talked to a doctor, tried ritalin and adderall and have settled on a low dose adderall routine that really works for me. It helps tremendously with focus and motivation, and if I am diligent about maintaining a good diet/exercise/sleep schedule, the side effects are very manageable with daily use. I still think about the modafinil days, because those were good times, and it was fun to have that all day I'm on fire feeling. Adderall is nice, but I can tell that if I upped my dose to get into the realm of intense focus that Modafinil used to give me, I would also be getting pretty "high" and the comedown side effects would probably be more unpleasant.

pvarangot · 5 years ago
The nootropics community is usually more about substances with reliable effects across the whole spectrum of neural fauna. Modafinil has side effects that are really bad for productivity in a substantial percent of the population, like it doesn't work or it's really bad for some people with GAD or OCD and people prone to addiction or with ASD.

I'm not a proponent of having drugs be "prescription only", people should be allowed to eat what they want if they don't harm anyone else... but I personally put Modafinil under my list of stuff that you probably may need some help with if you want to try it.

odiroot · 5 years ago
> I'm surprised modafinil isn't no. 1

Someone shared modafinil with me once. The effect is crazy.

As you say, it lets you focus on single task for quite a long time, without feeling tired. And I'm saying it as a person who can be easily distracted.

I never tried it again, not to mess with my brain.

meepmorp · 5 years ago
-afanils don't work for everyone. Modafinil makes me both jittery and tired, and I can't focus for more than a minute; kind of like I'm badly jet lagged and just need to pass out.
01100011 · 5 years ago
My problem with Moda/Armoda is that I feel like a tweaker when I'm on it, and I only take enough to get an effect. I get sweaty, physically stressed, and just generally feel like I'm taking something that is not in my body's best interests. I have to drink liters of water to avoid a headache. I also have noticed some of the dopamine effects(increased risk taking and addictive behaviors). I'm slightly bipolar though(type II, pretty mild) so maybe it's just not for people like me.

It does work pretty well for focus though, and is really nice for my middle-aged brain which often is tired throughout the day.

unwaryquerier · 5 years ago
Do you have a site you use to purchase your modafinil? And how did you decide dosage?

EDIT... and it looks like this is a controlled substance. I didnt know

sizzle · 5 years ago
Have you tried Dexedrine? It’s the right handed enantiomer of adderall which has less pronounced effects on heart rate, etc.
blacksmith_tb · 5 years ago
I always take theanine with my caffeine (that is, I drink tea).
jvanderbot · 5 years ago
I've recently switched over to green tea and really wish I had earlier.
markus_zhang · 5 years ago
Interesting. As a Chinese I used to drink tea but years ago I switched to coffee for better flavour. Maybe I should try milk tea instead.
imwally · 5 years ago
I’m addicted to matcha. Just so happens to have high levels or l-theanine.
asadkn · 5 years ago
I have personally observed something similar with black tea but I am not sure if's just the theanine + EGCGs or something else.

A while back, I noticed that 'chai' helps me focus and relax (improved mood, less anxiety, etc.) at the same time. It's made of milk, black tea, cardamom, cinnamon, and negligible/no sugar (personal preference).

I prefer coffee in terms of taste, but of all the things I have tried, this has been the best for me. Black tea alone doesn't have the same effect on me, nor does green tea, or coffee with or without milk/cream/sugar.

So I wonder if it's the combination that matter and not theanine alone.

ValentineC · 5 years ago
> A while back, I noticed that 'chai' helps me focus and relax (improved mood, less anxiety, etc.) at the same time. It's made of milk, black tea, cardamom, cinnamon, and negligible/no sugar (personal preference).

I know Starbucks et al market the above as 'chai', but I think 'masala' (as in 'masala chai' [1]) should be the keyword.

[1] https://en.wikipedia.org/wiki/Masala_chai

ac29 · 5 years ago
> It's made of milk, black tea, cardamom, cinnamon, and negligible/no sugar

Maybe you mean no added sugar? Milk has 1.5g of sugar / oz (about half that of orange juice, as a comparison).

sizzle · 5 years ago
I use l theanine everyday to avoid heart palpitations with coffee. Is there any long term damage I’m doing from this daily combo??
tayo42 · 5 years ago
Within minutes? Are you snorting it? can anything get through you that quickly orally? Sounds like placebo
netizen-936824 · 5 years ago
If consumed dissolved in a liquid on an empty stomach, it can be absorbed rather quickly.
nednar · 5 years ago
Would you also conclude that the study shows evidence that in a caffeinated body the theanine's only work is to reduce the effects of the caffeine?

What conclusions would you draw from that if you want to focus more?

Florin_Andrei · 5 years ago
Simple protocol: one coffee cup in the morning to wake up. Green or black tea through the day as needed.
marttt · 5 years ago
Somewhat related: In his recent book "This is Your Mind on Plants", Michael Pollan also discusses caffeine addiction. Transcript of an interview with him on Tim Ferriss' blog:

https://tim.blog/2021/06/30/michael-pollan-this-is-your-mind...

I've been off caffeine and yerba mate (of which the yerba I consumed daily for the past 9 or so years) for two weeks. Feels really great, I admit being somewhat less sharp mentally (for now), but I still get everything relevant done. And -- maybe yet I feel kind of more... mentally balanced? Imagine having less thoughts throughout the day, but the ones you have, you'll like more. :)

It's like my energy levels are much more consistent, no sudden drops throughout the day -- and that's even when I'm doing heavy physical work. (I'm a full-time forestry worker, tree planter, brush cutter these days -- now not even thinking about the usual midday yerba mate kick I used to rely on.)

The tiredness that sets in at night also feels much more calming. So IMO it's a highly recommended shift overall -- I guess just the first 4-5-6-7 days without coffee/strong tea may be really hard.

danenania · 5 years ago
Do you think doing a job involving more physical than mental labor made it easier to get through the withdrawal? It seems like pushing through the stupor is tough but doable for physical stuff, whereas with mental work (like programming) you can be pretty much knocked out of commission until the symptoms subside.
marttt · 5 years ago
> Do you think doing a job involving more physical than mental labor made it easier to get through the withdrawal?

Very probably, yes. IIRC, I have actually tried quitting yerba/coffee a few times earlier as well while doing mostly mental work. And I always failed. Currently my days in the forest consist of several 1.5h brush cutting sessions -- meaning, during that time, I am in nonstop movement, cutting the brush, unable to do anything else. During a break between the sessions, I am usually heavily dehydrated, so my body just wants a lot of water. I think I've even come to dislike the idea of having coffee or (really surprisingly) yerba mate at that point.

Currently I usually work 3x1.5h sessions every day, plus water drinking breaks and saw blade sharpening, so it's around 5-6 hours in the woods every day. And, in the forest you have no coffee shops, no other shops, no fridges. And, if you manage not to take coffee with you, there's simply no coffee at all nearby! I suppose that's the essential part of the whole trick.

I plan to return to mental work for the winter. I do think staying off yerba/coffee will be a struggle again for indoor work and/or cold season.

amacneil · 5 years ago
You don't have to quit caffeine cold turkey. You can just ramp down from n cups of coffee/day to 1 cup, then switch to n cups of tea/day (black or green) and ramp down to 1 cup, then switch to low-caffeine or caffeine-free tea, then stop entirely.

Have been off caffeine for several years now. Took probably a couple months to reach a point where I felt comfortable going into an interview or important meeting without it. Now I don't miss it at all, but if I ever do have it, a cup of decaf coffee will have me buzzing for hours, and an espresso will make me extremely uncomfortable and jittery - crazy that that used to be my baseline intake.

JohnBooty · 5 years ago
Not the person you asked but: absolutely yeah.

Coding and other such mental work is very tough for me unless a lot of factors line up. But I can stay focused on physical tasks even if I'm feeling like garbage - even something like tennis that's both mental+physical.

edit: Are you talking about sudden "cold turkey" quitting + the subsequent withdrawal? The answer to that is hell no -- if I try anything that foolish I'm really in for some hurt. Luckily as others have noted, there's no need to experience withdrawal if you taper dosage down over a week or two.

kossTKR · 5 years ago
Exactly, i find mental work close to impossible a few days after quitting caffeine. I can do social stuff to an extend and get manual labor stuff done, but not anything requiring initiative and self discipline.
themodelplumber · 5 years ago
Curious, do you use anything else? I like trying out various ideas on long or difficult hikes. One category that consistently helps is the anti-inflammatory category.

I've also tried some pretty interesting nootropics including one that was designed to support work in extreme environments, and the difference in feeling from caffeine was pretty wild. (I did have some pretty fascinating but unwanted side effects while getting the dosage dialed in, basically what I'd call super soldier mode, so I hesitate to mention it by name...)

marttt · 5 years ago
Nope, nothing else. I have been heavily relying on yerba mate -- one sip or tiny cup works wonders during heavy tree planting sessions. This has always been my secret weapon, because, in contrast to coffee, it doesn't seem to cause a feeling of fluid loss.

Also, during tree planting, I only occasionally eat a few carrots or other vegetables to help me finish the day. After that, a well-deserved meal will follow.

Disclaimer, though: I have experimented with intermittent fasting for several years, so I suppose my body has already adapted to long periods of hunger. Be careful with this stuff, though, and don't listen to my silly advice.

actually_a_dog · 5 years ago
I'm not sure if this is exactly what you're getting at, but, in the anti-inflammatory category, glucosamine and aspirin are both great, and have some pretty good science behind them.
navi0 · 5 years ago
I’d be interested in talking with you about a project I’m working on (forestry-related, not caffeine-related), if you’re open to it.

Info@madronus.com

thomasfl · 5 years ago
I simply can't understand why it is still uncommon to sleep at the office, while they give this psychoactive drug called caffeine for free.

According to wikipedia, caffeine is the world's most widely consumed psychoactive drug.

newsbinator · 5 years ago
If you sleep at the office you're wasting time and slacking.

If you can keep your eyes open while staring at an open email you're being productive.

CountDrewku · 5 years ago
Sadly this is the truth. It's all about perceived work and not actual work.

Dead Comment

swader999 · 5 years ago
You need to master the art of sleeping in your office chair with your back to the door. Keep an interesting piece of paper handy to be reading when someone comes in instead of staring at a blank screen.
Macha · 5 years ago
You mean you're not in a giant open office? Nice.
mbil · 5 years ago
Since working from home due to the pandemic I’ve been able to wean myself completely off caffeine. To not get tired in the afternoons, I take a 15-20 minute nap each day after lunch. I think this has been good for me, and I’m worried that when I have to go back to the office I’ll be dependent on coffee again.
stronglikedan · 5 years ago
I wish I could nap. For me, a nap turns one normal day into two short days - a bright productive one and a dark groggy one. I've even tried the coffee-then-20-minute-nap method to no avail.
unmole · 5 years ago
It's fairly common in China. Sure you have to 996 but that includes an hour for napping post lunch.
ehnto · 5 years ago
First time hearing of 996, for anyone else curious that's a 9am-9pm 6 days a week work schedule.
chalst · 5 years ago
Couldn't fit title and date into 80 chars, so the story title is edited:

     Caffeine and theanine exert opposite effects on attention under emotional arousal, Grace E Giles et al., Canadian Journal of Physiological Pharmacology, January 2017.

0xTJ · 5 years ago
I'd call the current title of this post blatantly wrong. In common use, "emotional arousal" and "arousal" have very different meanings.
chalst · 5 years ago
I'm still able to edit the title: care to suggest another version that fits within 80 chars? The title alone fits, one char to spare, but I didn't want to pass off a 4-y.o. paper as if it was pharmacological news.
TheFreim · 5 years ago
Almost skipped an otherwise interesting topic because of this.
nkozyra · 5 years ago
Agreed; in fact, it makes two points that have different impact:

> Consumed together, caffeine and theanine exert similar cognitive effects to that of caffeine alone, but exert opposite effects on arousal, in that caffeine accentuates and theanine mitigates physiological and felt stress responses.

This is inline with the anecdotal evidence about theanine's mitigating effect on caffeine & stress.

Deleted Comment

sunshineforever · 5 years ago
I understood "arousal" to be the emotional sort of arousal, but I see your point.
dukeofdoom · 5 years ago
I noticed when I switched from cream to oat milk, the coffee hits a little differently. It feels stronger. I'm not sure if its some interaction with milk. But paper should consider what is consumed with the coffee too. Some people will add sugar, and some even add butter.
bserge · 5 years ago
I'm... using caffeine powder sublingually... Fast acting, no stomach problems.

Different brands have noticeably different strength, though, gotta be careful. The less bitter the powder, the better imo.

holdenlucas · 5 years ago
In your experience, what is the brand with the least bitter powder?
CountDrewku · 5 years ago
Probably something to do with the fat. There's something called bulletproof coffee or butter coffee where they add butter/coconut oil/mct oil and I think it's supposed to satiate you more as well as keep you from getting all jittery.
swader999 · 5 years ago
Coffee might bind to the cream more and then absorb slower. I notice with a teaspoon of butter I get a much less jittery experience. (The bullet coffee thing).
PascLeRasc · 5 years ago
Have you tried drinking it black as well? I wonder if it’s added sugar that a lot of oat milks have or something drowsy-inducing in milk.
dukeofdoom · 5 years ago
I haven't really. I switched to Oatmilk, because I was getting stomach cramps about once a month. Still haven't figured out if the milk was causing it, because it happened again after the switch. Maybe its something in the coffee, maybe the pesticides they use or maybe I don't clean the coffee machine frequently enough. I drink as many as 5 cups in day. So I'm might have a bit of a problem.
minsc__and__boo · 5 years ago
Oat milk has more carbs than the rest of the alt (?) milks, and sometimes more than cow. Def could be the reason for feeling better.
pixelbreaker · 5 years ago
possibly the lipids in cow's milk slow the ingestion of caffeine. depends on the oat milk you drink and how much fat it has in its ingredients.
scns · 5 years ago
Oat milk has added vegetable oils like sunflower, which have higher amounts of unsaturated fats i think. Someone mentioned coconut oil, which is high in satarated fat, could make a difference.
bitshiftfaced · 5 years ago
I have a theory that the jittery/anxious feeling people say they get from caffeine is mainly due to the size of the dose and "quickness" of it. If you find that theanine fixes it, then great. But I'd also suggest trying 100 mg time-release caffeine and see how it goes. You might be surprised. This also has the benefit of needing less total caffeine while lasting you longer through the day. (Just a heads up: many brands only say they're time-release but don't seem to actually have the coating/capsule/matrix that you'd expect from an actual time-release pill.)
toxik · 5 years ago
Agreed, if I drink a lot of strong coffee fast, I’m basically shaking for the next hour or so.

My solution is dilution. I put about four cups worth of coffee into the filter, and then 1.3 L water in the tank. The result is very weak coffee that you can drink throughout the day, keeping you mildly caffeinated and hydrated simultaneously.

If you’re making coffee for people who can’t accept watery coffee, just brew normally and add water afterwards. The Italians in the office will curse your name, but that’s just a sign you’re doing it right.

ehnto · 5 years ago
The Italians in your office would have wanted espresso!

That's actually an interesting point, we're generally talking about coffee as if it's all the same, but I see people here talking about instant grounds, drip coffee and then there is espresso, I'm sure they all work out quite different. If you're used to grinding your own beans you'll know different beans have different caffeine amounts, and different extraction methods all have different yields.

Where I am it's all espresso, thanks to Italian immigrants bringing over stovetop espresso kettles in the 40s and jumpstarting our now incumbent coffee culture. I've never even seen a drip coffee machine, it's espresso machines in petrol stations, offices, cafes, restaurants, people's homes.

If I pull an espresso shot for too long it's going to have more caffeine in it than had it pulled really quickly, even though it's the same amount of coffee/water solution in the cup. So one person's four cups a day is rarely going to match another persons four cups a day. I'm sure it's the same for instant coffee brands or grinds too, when you take it all into consideration it's going to be hard to know what caffeine intake anyone has.

eloff · 5 years ago
I don't like watery coffee, so I mix mine 2/3 decaf. I have 4-5 cups throughout the morning. It keeps it a nice, even caffeine hit.
ehnto · 5 years ago
I drink my coffee over the course of a few hours, if I have to slam it down, say I suddenly need to leave the office, it makes me feel incredibly anxious and shaken. Taken slowly it has no noticeable effect except to my ability to get tired a tonight, I drink it entirely for the taste so that's actually a bummer. I've considered switching to decaf.
Tempest1981 · 5 years ago
I find it gets cold fast. Do you have a heated mug? Suggestions?
luxurytent · 5 years ago
I switched from a double shot in the morning (my only cup of the day) to two single shots, spread out over ~3 hours. My first is at 6 when I first wake, then another around 10 after my run and breakfast. Definitely feel less of the jitters.
JohnWhigham · 5 years ago
I've seen this in many places; people will take L-theanine to counteract any jittery effects of caffeine, but I never noticed anything. What L-theanine is helpful for is going to sleep and calming one's mind.
danielam · 5 years ago
I have. I can drink green tea (including strong matcha), which does contain l-theanine, probably daily, but I cannot drink coffee daily for more than maybe 2 weeks without experiencing adverse affects. Even one cup of coffee can leave me agitated. Supplementing coffee with l-theanine completely eliminates agitation.
amelius · 5 years ago
Can you drink cola without adverse effects?

Because I can. And coffee gives me issues after a week or two.

Therefore something seems wrong about giving caffeine all the blame.

fighterpilot · 5 years ago
Black tea is also very high in l-theanine. Regular green tea is not, but matcha (which you consume) is as well.
tylermenezes · 5 years ago
I am extremely sensitive to caffeine, it makes me super jittery and I can feel my heart race.

For the last 4 years I've been adding 100mg of pure caffeine powder and 125mg L-theanine to a non-caffinated morning beverage. I even had someone secretly add or not add the L-theanine without telling me for a while, so it's as well controlled as an n=1 study can be.

The difference is pretty night-and-day for me, but obviously ymmv.

There's a lot of genetic difference in caffeine processing, and I happen to have almost every genetic variant associated with high sensitivity I could find studied.

bserge · 5 years ago
Taurine and GABA synergize similarly with caffeine.
srean · 5 years ago
Indeed. When I am over-caffeinated I am energized but not exactly effective. L-theanine centers my mind.
deregulateMed · 5 years ago
I wish caffeine made me feel anything.

I would need over 24 oz of coffee for anything.

But at that point I'm pushing potentially unsafe levels..

I wish we were taught more about taking drugs. Use caffeine since it's legal, for an example.

"Don't have caffeine 2 days in a row. Ask yourself if you really need the energy or are thirsty/bored. Etc...."

You could apply the same to alcohol to reduce alcoholism.

n8cpdx · 5 years ago
You might have adhd. I fall into extremely high doses because a high level of stimulant use is needed to get to a “normal” baseline.

Of course tolerance is also a factor. I’ve been reducing my intake, for a while it was well over 1g/day, and that wasn’t really about trying to “feel” anything.

UI_at_80x24 · 5 years ago
>I wish caffeine made me feel anything.

(intentionally NOT quoting the remainder of your post)

The only time I ever felt anything from caffine:

I was working the midnight shift. (At a service industry job, there were no customers so it was dead.)

I took:

  2 caffeine pills
  4 coffee's
  2 cans of coke
It worked. I was very jittery, and had the shakes. But I survived the shift, and by the time the shift was over (7am) the sun was up, and I had a 1 hour drive to get home.

I was also surprised to learn while driving Truck, that some US States outlawed caffeine pills. (Ohio) It might have been available at a drug store though, I only had access to truck stops.

taeric · 5 years ago
Neat that the point is that they offset each other. Not just that they have opposite effects used individually, but when combined they are no different from a placebo.

I'll have to dive more on what the local processing means.

jonnycomputer · 5 years ago
In the context of the experiment its whether participants paid attention to global or local features when making comparisons. Imagine a target object, a square made up multiple triangles. Then you have two options to select from: a square made up smaller rectangles (global similarity), or a hexagon made up of triangles (local similarity). Anyway, that's how its explained in the article.