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xkcd-sucks commented on Are Saunas Good for You?   economist.com/science-and... · Posted by u/Anon84
nabla9 · a day ago
I'm a Finn so I'm biased.

From general systems biology perspective everything that moves body metabolism away from it's normal state for short time seems to give benefits, exercise, cold, heat, hunger, ... allostatic load that is not chronic is generally good.

xkcd-sucks · a day ago
My hot take hopeful guess is that heat shock causes upregulation of protein degradation / chaperone activity, thereby disrupting protein aggregation involved in AD, PD, et all. One can hope
xkcd-sucks commented on Ask HN: Non-Smart TV Recommendations?    · Posted by u/behnamoh
xkcd-sucks · 2 days ago
It is not technically a television, but a good short throw projector has suited my household's needs perfectly; i.e. gaming and streaming from devices
xkcd-sucks commented on 'godfather of AI' reveals the only way humanity can survive superintelligent AI   cnn.com/2025/08/13/tech/a... · Posted by u/rbanffy
xkcd-sucks · 9 days ago
If "superintelligence" is such a big deal, how is it that e.g. MENSA members haven't taken over the world yet? Is there evidence of the assumed "superintelligence/dominance" equivalence in existing human population data?
xkcd-sucks commented on Lithium compound can reverse Alzheimer’s in mice: study   hms.harvard.edu/news/coul... · Posted by u/highfrequency
kovek · 17 days ago
Could you share some sources that show this to be true?
xkcd-sucks · 17 days ago
It's like kind of challenging to prove this kind of negative, and the supposed proof here comprises no more than pedigreed words on a page, but here consider the section "What constitutes a good model for AD?": https://sci-hub.se/https://www.nature.com/articles/s41583-01...
xkcd-sucks commented on Windsurf employee #2: I was given a payout of only 1% what my shares where worth   twitter.com/premqnair/sta... · Posted by u/rfurmani
lovich · a month ago
Has it been worth it in a while? This is a legitimate question as I am on the east coast and wonder if it differs from the west coast environment.

At least in my anecdotal experience, everytime I’ve entertained a startups offer in the past decade it’s been either something like engineer #1, 3% equity and no you cannot see the cap table or other agreements with investors, or something like 10k units at 25 a share when we’re on series z, and you lose them if you leave, and you can’t sell for 6 months if you leave, and the investors have priority on payment if we sell for less than our valuation and yadda yadda yadda.

I mentally just valued the equity as 0 in the compensation with all those limitations on liquidating them and never understood why anyone joined a startup

xkcd-sucks · a month ago
Oh also there is the trick where the startup gets sold a little under its strike price and the execs each get signing bonuses > book value of company as sold

Dead Comment

xkcd-sucks commented on Nightmares Linked to Faster Ageing and Premature Mortality   emjreviews.com/neurology/... · Posted by u/gnabgib
NoPicklez · 2 months ago
Interesting how I was reading an article yesterday talking about how cheese/dairy might give people nightmares, linked to GI distress and lactose intolerance.

It could be a factor that GI distress and food intolerances contribute to nightmares due to additional stress and inflammation within the body, causing premature mortality over the course of someone's life.

xkcd-sucks commented on CEOs Start Saying the Quiet Part Out Loud: AI Will Wipe Out Jobs   wsj.com/tech/ai/ai-white-... · Posted by u/planetjones
xkcd-sucks · 2 months ago
All of whom want to trade on expectations of future labor cost reductions which haven't actually happened yet, so take with a grain of salt
xkcd-sucks commented on How the Alzheimer's Research Scandal Set Back Treatment 16 Years (2022)   discovermagazine.com/the-... · Posted by u/walterbell
m3kw9 · 2 months ago
So why do researchers is still hell bent on believing the beta amaloyd theory? I get voted down every time I ask this
xkcd-sucks · 2 months ago
There's a lot of researchers in a lot of roles and it turns out finding targets is just one of those roles, the rest focus on optimizing therapies against those targets and they like having well defined targets to work on.
xkcd-sucks commented on Whatever happened to cheap eReaders?   shkspr.mobi/blog/2025/05/... · Posted by u/blenderob
0xffff2 · 3 months ago
Can you give an example of a restaurant you have in mind? I thought I lived in a HCOL area, but your number seems off by nearly a factor of 2 to me. Plus, considering how infrequently many people eat out at all, I'm not so convinced that this specific argument is a good one.
xkcd-sucks · 3 months ago
I'm thinking sit down waited upon dinner for two, "second/third tier cities" in Northeast USA mostly - In 2025 you might see $30/head "restaurant week prix fixe" but those places are usually closer to $50/head if there's anything additional to an entree

And yes, we have kind of a restaurant death spiral because it is expensive to eat out.

u/xkcd-sucks

KarmaCake day4002August 20, 2014View Original