It is trivial to get pihole working with DoH. Just pair pihole with DNSCryptProxy.
Sure, but its not what pi-hole does or support. You need to install another software and forward requests to it. Technitium DNS has this feature built-in along with support for DoT and DoQ, including support for DoH/3.
https://blog.technitium.com/2015/05/technitium-bit-chat-rele...
I had released that 10 yrs ago lol.