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nikolay commented on FDA approves new Covid-19 vaccines in US but limits who can get them   theguardian.com/us-news/2... · Posted by u/xworld21
acdha · a day ago
If people didn’t want them, Kennedy wouldn’t have had to prevent people from getting them. All of the attacks on scientists, experts being fired so they can be replaced with cranks, etc. happened because the preponderance of evidence shows mRNA vaccines are safe and effective, and would have been approved under science-based policies.
nikolay · 14 hours ago
Why would I sane person keep putting these uncontrollable spike-protein-producing machines in their bodies?! Don't they read the studies that the spike protein is found in all kinds of organs and tissues years after vaccination, mainly in the brain though? The protein is considered toxic. There's also an IgG4 issue with mRNA vaccination. Many long haulers actually have vaccine injury - I am one of them. Right after the first shot I got myocarditis - severe palpitations, and going for the second shot I told them about it, but they said that it's normal!!! The second short was way worse and I had 2-3 palpitations per minute for over 6 months. I couldn't sleep normally due to the stress palpitations cause! Nobody cared about this, and I have a damage heart from the vaccine, in addition to all other symptoms, which onset is immediately after the vaccine - headaches, poor sleep, 4-6-month periods of heavy palpitations, hair loss, etc. So, this is no flu shot. This is a brand-new class of medications, and it needs to be studied. We're no longer in a pandemic and we should be careful about these vaccines, which, by the way, are not sterilizing either, so, they hold a very little epidemiological value.
nikolay commented on Paracetamol disrupts early embryogenesis by cell cycle inhibition   academic.oup.com/humrep/a... · Posted by u/XzetaU8
littlestymaar · a day ago
Please ask Gemini to explain you that you cannot generalize over small samples like your two kids or a few dozen kids from your childhood…
nikolay · 21 hours ago
Literally no kids of a mid-size town in Bulgaria had no head injury riding a bike w/o helmet since I was kid. Not sure where you got the two or a dozen. In fact, a dozen is a fairly good sample size in terms of medical studies, sometimes done with conclusions done with smaller cohorts. In fact, the first COVID-19 booster by Pfizer was only tested on mice, not on a single person even, yet it was administered to billions of people.

Helmets and bike gear are in industry and American industries have powerful lobbies.

nikolay commented on Paracetamol disrupts early embryogenesis by cell cycle inhibition   academic.oup.com/humrep/a... · Posted by u/XzetaU8
littlestymaar · 3 days ago
> They all slept perfectly well with fever, so, there's no such thing as a febrile insomniac kid.

Please stop believing your sample of 3 kids is representative of the entire population. You were lucky to have kids who sleep well and that's good for you, but that doesn't make other parents lazy or irresponsible.

> I'm tired of parents who overprotect their children

You know what's even more tiring? Parents who judge other parents while not knowing anything about kids in general just because they happened to be lucky on one particular topic. You won't be lucky all the time though.

> to forcing them to wear helmets

I hope you won't regret saying that ever in your life, but being anti-helmet really is as idiotic as being an antivaxxer.

nikolay · a day ago
In my childhood, when the movie BMX Bandits (1983) [0] was super popular, helmets and any kind of protection did not exist. We did all kinds of crazy stunts, influenced by the movie. I don't recall any harmed kid among tens if not hundreds. Scaped knees and elbows - sure, but that's all!

[0]: https://www.imdb.com/title/tt0085204

nikolay commented on Paracetamol disrupts early embryogenesis by cell cycle inhibition   academic.oup.com/humrep/a... · Posted by u/XzetaU8
littlestymaar · 3 days ago
Ah, a genius that need an artificial brain to overcome its lack of literacy and is somehow proud of that.

How surprising given the rest of the conversation …

nikolay · a day ago
It's not a brain, its a statistical summarizer, but based on the result, it seems to work better than your brain, obviously!

Dead Comment

nikolay commented on Paracetamol disrupts early embryogenesis by cell cycle inhibition   academic.oup.com/humrep/a... · Posted by u/XzetaU8
littlestymaar · 4 days ago
> But it's the truth.

No it's not, in many case there's just no way the parent can tell something is about to go wrong.

> Something that has just a 2% incidence should not dictate 98% of the treatments.

This isn't the same argument, and I would agree if it was true, but you're distorting numbers as the actual prevalence estimations lie between 2 and 14%[1].

Now you could make the argument that 10% is low enough of incidence it shouldn't dictate the treatment of the other 90%, but that's not what you're doing, instead you are blaming helpless parents and cherry picking numbers, making nothing but noise.

Oh, and by the way, most parents aren't in fact giving their kids paracetamol for that particular reason (as most parents are simply unaware of the existence of febrile seizures), but to help their children sleep and rest (and so themselves can sleep). And in fact, resting being key in innate immunity efficiency, I'm not particularly convinced about the effectiveness of letting your kids cry all night because of the pain and fever. You do what you want with your own kids, but there's no justification for insulting other parents.

Good day.

[1]: https://www.bmj.com/content/351/bmj.h4240

nikolay · 3 days ago
I have 3 kids, all grown up and healthy. They all slept perfectly well with fever, so, there's no such thing as a febrile insomniac kid. High fever has a potent detox element as you sweat out the toxic metabolites. I'm tired of parents who overprotect their children while harming them this way - there are so many studies - from overdrugging kids (thank God that most anti-cough drugs are now off the shelves), to forcing them to wear helmets, no go alone, etc.
nikolay commented on Paracetamol disrupts early embryogenesis by cell cycle inhibition   academic.oup.com/humrep/a... · Posted by u/XzetaU8
littlestymaar · 4 days ago
> But it's the truth.

No it's not, in many case there's just no way the parent can tell something is about to go wrong.

> Something that has just a 2% incidence should not dictate 98% of the treatments.

This isn't the same argument, and I would agree if it was true, but you're distorting numbers as the actual prevalence estimations lie between 2 and 14%[1].

Now you could make the argument that 10% is low enough of incidence it shouldn't dictate the treatment of the other 90%, but that's not what you're doing, instead you are blaming helpless parents and cherry picking numbers, making nothing but noise.

Oh, and by the way, most parents aren't in fact giving their kids paracetamol for that particular reason (as most parents are simply unaware of the existence of febrile seizures), but to help their children sleep and rest (and so themselves can sleep). And in fact, resting being key in innate immunity efficiency, I'm not particularly convinced about the effectiveness of letting your kids cry all night because of the pain and fever. You do what you want with your own kids, but there's no justification for insulting other parents.

Good day.

[1]: https://www.bmj.com/content/351/bmj.h4240

nikolay · 3 days ago
The vast majority of these seizures are benign. If your child had a febrile seizure, then there's a 30% chance of having it again, so, then you have some excuse to keep their fever under control (hopefully not with Tylenol as there are other antipyretics, too). Here's a nice summary by Gemini:

Key Takeaways

- No Lasting Damage: Simple febrile seizures do not cause long-term brain damage, intellectual impairment, or learning disabilities.

- Benign Nature: Despite how terrifying they are to witness, febrile seizures are considered benign events in the vast majority of cases.

- Focus on Reassurance: The primary goal for healthcare providers is to reassure parents and caregivers, providing them with the knowledge and tools to manage a fever and understand the low risk of lasting effects.

nikolay commented on Review of Anti-Aging Drugs   scienceblog.com/joshmitte... · Posted by u/XzetaU8
JPLeRouzic · 6 days ago
How do you create a well-connected motor neuron with a 3-foot or one-meter-long axon? Or brain neurons that are highly connected to other areas?

I would appreciate any pointers to a scientific article that describes this.

nikolay · 4 days ago
Peripheral neurons can regenerate [0]. Heart muscle also can repair through other factors [1].

[0]: https://pmc.ncbi.nlm.nih.gov/articles/PMC6336700/

[1]: https://www.sciencealert.com/new-study-reveals-more-about-ho...

nikolay commented on Aspirin Confers No Long-Term Heart Benefits in Older Adults   medscape.com/viewarticle/... · Posted by u/wjb3
nikolay · 4 days ago
The issue with these studies, according to what I've heard, is that they use the wrong type of aspirin - they use enteric-coated aspirin, which doesn't work the same way. Instead, if you take pure aspirin (you can only find it for veterinarian use) together with vitamin C and/or DGL (Deglycyrrhizinated Licorice), then you protect your stomach from aspirin, and it acts as it's supposed to act. Georgi Dinkov of Ray Peat's fame told me once that another trick is to take aspirin with gelatin, which also coats and protects your stomach lining. I discussed different novel aspirin formulation such as the disappeared now Vazalore. I still think the easiest way is to take Aspirin C by Bayer in Europe and breat it into 4 pieces, because the asprin dose is pretty high otherwise, which is good if you have an acute problem, but it's a bit too much for a daily use.
nikolay commented on Paracetamol disrupts early embryogenesis by cell cycle inhibition   academic.oup.com/humrep/a... · Posted by u/XzetaU8
locallost · 4 days ago
People do that because they haven't been "educated" (even superficially) about what fever really is, which is your body working hard to fight of the infection. And messing with it is counterproductive.

They also do it with their kids because they want to help them. Also, some people have a lot on their plate, calling them lazy is not right thing to do. I have health insurance that covers me when my kids are sick (not in the US), so I can take care of them "properly ". This doesn't make me more responsible and someone else that works two jobs and can't afford to have sick kids lazy.

Also, I don't lower fever, even with my kids unless it prevents them from sleeping. But overstated is relative, it's happened to the kid next door from me. You don't want to be careless with infants.

nikolay · 4 days ago
They are lazy if they don’t educate themselves about what they are doing and what they are giving their children. Don’t get offended. I’ve never done anything health-related to my kids without doing thorough research. I’ve witnessed four major medical mistakes made right in front of me in Orange County, California, in some of the best medical facilities and by the best pediatricians in the area! That’s why I don’t blindly trust anyone, whether it’s a doctor or not. I use critical thinking and always look for alternative advice. Doctors often find me a nuisance, but that’s okay with me. Just try asking a doctor when they prescribe Tylenol for a fever: “Why should I try lowering their fever?” or “Why should I give them Tylenol exactly?” The hepatotoxicity of acetaminophen occurs when the production of the toxic metabolite NAPQI exceeds the liver’s glutathione detoxification capacity, which can happen quite frequently during infections! So, then ask your doctor: “Doesn’t it make sense to give them NAC with Tylenol as well, just in case?” They won’t know what to say, trust me!

u/nikolay

KarmaCake day7898March 16, 2007
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