Readit NewsHere is the drug trial results for EMERGENT-2 which was one of the two phase-3 trials that lead to the approval.
I think its striking that the trial is only 5-weeks long and this medication gets approval.
On very quick review, it looks like there are is significant association between HERV genetic factors and specific diagnoses given PIP. However, what's not clear to me is effect size or correlation coefficient.
I'm not sure if I'm missing this or it's not reports. There might be a relationship, but at a very small percentage.
In my very humble opinion, the diagnostic category of ADHD isn’t particularly helpful, it’s too broad, one person with ADHD looks completely different from another. Additionally it’s very easy to identify and over-identify with diagnosis to the detriment of your personal potential. It’s a self-fulfilling prophecy and all to common trap.
As other have said, you can go see a psychiatrist and they’ll evaluate you and maybe you end up with stimulant meds. Attentional issues are not just due to ADHD, they can be part of anxiety, depression, PTSD, etc.
If you do get an ADHD diagnosis, The meds help some people (actually they make everyone focus, i.e. why they gave them to fighter pilots). They also suck for other people.
What I believe will be helpful is learning how to live your life with your unique mind. If you can find a therapist who practices mindfulness-based interventions, (ACT, MBCT, DBT) it could be incredibly beneficial. Good luck on your journey!
With that said, I do agree with the proposal that if a kid has already had covid then why vaccinate them if the general consensus is that the vaccines only provide limited protection for a few months. All for vaccinating high risk people and I am vaccinated against covid with a booster from when they first came out but will not get another booster now that I have already had Covid. Omicron in general for most people is no worse than the flu, unpleasant but bearable. I fully understand the rush to vaccinate adults in the beginning when Delta was raging and we had limited understanding of the virus. Luckily Omicron is dominant now it seems to be much less damaging. This is not to downplay the very real consequences and deaths that do occur still from Covid. At this point in time my whole family has had it and I have accepted it as endemic and moved on.
"Then they ignored natural immunity. Wrong again. The vast majority of children have already had Covid, but this has made no difference in the blanket mandates for childhood vaccines. And now, by mandating vaccines and boosters for young healthy people, with no strong supporting data, these agencies are only further eroding public trust."
What the fuck is "natural immunity" when we have had 5 variants of omnicron and infection doesn't provide immunity to the other variants?
The real crime IMO, is that... U.S. Public Health Agencies Aren't ‘Following the Science,’... the science of how we could actually reduce spread and decrease the 350~ DEATHS per day adding to the more than 1 Million dead already.
I imagine this was a tough call for a PM, with a lot of cases to consider and account for given this is so embedded in the Drive product DNA.
Looking at your building location, I see you're near the Hoboken stop. That's why you have the Hoboken departure times hard-coded in the departure_times.js.
I thought the file was just the line schedule and then you'd have to pick a station, but I see now it's just the schedule for the Hoboken station?
"There is no evidence that sleep was universally segmented, and there is also little evidence that segmented sleep is better. A 2021 meta-analysis of studies on biphasic sleep schedules found that segmented-sleeping subjects actually reported “lower sleep quality … and spent more time in lighter stages of sleep.” One reasonable takeaway is that biphasic sleep is like anarchical foraging: Both might have well served some ancient populations some of the time, but neither of them offers a clear solution to modern problems."
> Results from additional trials, including the identical EMERGENT-3 trial and the 52-week, open-label EMERGENT-4 and EMERGENT-5 trials, will provide additional information on the efficacy and safety of KarXT in people with schizophrenia.
EMERGENT-4 and EMERGENT-5 concluded last year [1], which was the reason for the approval. EMERGENT-2 was mostly a milestone Karuna Therapeutics used to get enough funding for the rest of the trials and inform their design.
[1] https://news.bms.com/news/details/2024/Bristol-Myers-Squibb-...