The symptom profile of long covid is very close to lyme disease, another disease people actually get but also many more people claim to have without evidence.
I'd like to see the overlap between long covid sufferers, IBS, lyme disease, people with a gluten allergy, PCOS etc and the level of evidence that they actually have those diseases.
e: I'm downvoted but this is one of the only treatments with best-in-class evidence for its effectiveness in treating long covid as well as CFS and IBS. The body is a complex organism.
Can you share any relevant resources or ideas you've gotten on reducing the opportunists and increasing butyrate production? I've coaxed and cajoled my MMC and other digestive processes back into shape, or so it seems, but am struggling on the microbiome angle. It's tricky because the list of foods that trigger symptoms is insanely long, so it's hard to get creative and experimental as far as that goes.
The tricky thing with increasing butyrate production is that everyone's gut dysbiosis is different - and therefore, a prebiotic that works for one person may make someone else's condition worse. For example, I have big blooms in my Prevotella Copri population which would consume Inulin and make my butyrate production worse - but in people without a Prevotella Copri overgrowth, Inulin would improve their butyrate production.
I would look into 16S microbiome testing (I use Biomesight) and use that as a guide, as well as slowly trialing interventions and monitoring symptoms. None of this is perfect and you kinda have to be on the bleeding edge of science/alternative medicine to figure things out.
When I started investigating it (my coping mechanism during panic attacks) I discovered that the vagus nerve travels next to the esophagus through the diaphragm.
So my complete layman explanation was that the stomach pushes through the diaphragm during a hiatal hernia -> it rubs against the vagus nerve -> panic attack symptoms.
I might need to add the study of vagus nerve to "why haven't we studied this about the human body more" -list along with gut bacteria composition.
It has also been used quite extensively to combat post-covid neuropsychiatric symptoms.
I think the link here is that increased LPS/endotoxin production by your microbiota can induce acid reflux, cause neuroinflammation and psychiatric symptoms. Low acid production itself can result in a more inflammatory microbiome further exacerbating the problem. Long term fix would be working on the migrating motor complex, improve motility/gastric emptying and rebalance the microbiome by reducing gram-negative bacteria/pathobionts and increasing butyrate production via selective feeding. [I'm not a doctor, this is just the direction I've been working on things myself]
You've got Wembley - massively built up, loads of carparks gone and building in it's place. Then you've got the Millenium Dome, one big car park in 2007, one big car park in 2023.
Buddhist contemplative traditions predate Christianity, and arose in distinct geographic locations, so nobody's de-Buddhizing anything here. Authentic understanding of the practices doesn't need to be a sectarian monopoly.
The uniquely indifferent, secular practice of "cafeteria Mindfulness" is the only novelty. It's exactly the M.O. of science: dissect a living thing and run tests until you think you know what substance makes it tick, then you isolate it, independently synthesize that substance, patent it, mass produce it, and then you wonder why you've got such shitty results in practice, and then you cover that up along with the adverse side effects, and charge the insurance companies triple profits.
Excess deaths have been high all year and this is likely to remain the case for the next decade. We’ve obliterated the health service and also damaged the economic engine to pay to fix the problem.
(And I’m still downvoted. Open your eyes people, it’s basically Stockholm syndrome at this point!)
They cut the vagus nerves of rats and see behavior change.
Which makes sense to me - when "brains" first evolved, the connection to the stomach would've been the prime connection.
So they also seem to be effective via the enteric nervous system!