Diffraction gratings are amazing. Is it possible to make one with a 3d printer?
You can order them super cheap and in bulk from a variety of retailers. Ranging from simple toy things to rolls of it
Readit NewsLet them have some excitement, God knows Tulsans need it
This is in OKC, not Tulsa. Tulsans have plenty excitement with the opening of the atrociously bacteria infected Zink Lake running through the middle of the city: https://experience.arcgis.com/experience/d1473cd55d8d40e48c4...
getoffmycase commented on R: Introduction to Data Science (2019) rafalab.dfci.harvard.edu/... · Posted by u/tosh
> I can’t remember the last time a library incompatibility led to a show stopper.
Oh, it’s very common unless you basically only use < 5 packages that are completely stable and no longer actively developed: packages break backwards compatibility all the time, in small and in big ways, and version pinning in R categorically does not work as well as in Python, despite all the issues with the latter. People joke about the complex packaging ecosystem in Python but at least there is such a thing. R has no equivalent. In Python, if you have a versioned lockfile, anybody can redeploy your code unless a system dependency broke. In R, even with an ‘renv’ lockfile, installing the correct packages version is a crapshoot, and will frequently fail. Don’t get me wrong, ‘renv’ has made things much better (and ‘rig’ and PPM also help in small but important ways). But it’s still dire. At work we are facing these issues every other week on some code base.
I basically don’t use anything outside of tidyverse or base R because of the package dependency issues.
getoffmycase commented on Is something bugging you? antithesis.com/blog/is_so... · Posted by u/wwilson
This might be the best introduction post I've read.
Lays the foundation (get it?) for who the people are and what they've built.
Then explains how the current thing they are building is a result of the previous thing. It feels that they actually want this problem solved for everyone because they have experienced how good the solution feels.
Then tells us about the teams (pretty big names with complex systems) that have already used it.
All of these wrapped in good writing that appeals to developers/founders. Landing page is great too!
The entire testing system they describe feels like something I can strive towards too. They make you want their solution because it offers a way of life and thinking and doing like you've never experienced before
getoffmycase commented on Where did DNA come from? geneticsunzipped.com/tran... · Posted by u/andsoitis
What are the proper qualifications to criticize evolution?
getoffmycase commented on Where did DNA come from? geneticsunzipped.com/tran... · Posted by u/andsoitis
> Biology does not act like a computer. You cannot reduce biology to an operating system
Nobody is doing that. Analogies are drawing rough outlines in the thought-space[0], they aren't a definition. As such, they are helpful.
--
[0] - Or latent space, if I want to make an analogy inside the analogy apologia.
The fundamentals of biology are not difficult to grasp. Evolution, DNA -> RNA -> Protein, basic cell signalling, etc are all really easy to grasp with just the tiniest bit of effort. There's really no place for bad analogies, especially such a misleading one.
Sorry to bite your head off, but the reason that I'm passionate about this topic is, and I'm not joking, young earth Creationism. An analogy like the grandparent is something simple to grasp by many people, and then the Creationists can quickly turn around and say, "Well you see how biology is like a computer; somebody built a computer; therefore, God created us in six days, 6000 years ago."
getoffmycase commented on Where did DNA come from? geneticsunzipped.com/tran... · Posted by u/andsoitis
DNA: file.c
polymerase: gcc (transcribes DNA→RNA)
RNA: file.o file.m file
(the last one is mRNA)
ribosome: ./file (translates mRNA→Protein)
protein: (program in RAM)
epigenome: (program in RAM changes file.c)
RNA world: (different file.o's messing with
each other by some unknown program,
eventually giving rise to stable
file.c files)If I had a nickel for every terrible biology to computer processes analogy I saw on this website since joining, I’d probably have enough money to buy a beer. Which is what I feel I need after I see something like this.
Biology does not act like a computer. You cannot reduce biology to an operating system
getoffmycase commented on A look at the Mojo language for bioinformatics viralinstruction.com/post... · Posted by u/blindseer
As someone who is considering a switch from generic software engineering towards bioinformatics, what would you say the pain points are?
If this is not the way to remove workflow friction, what is?
Honestly the major pain point is that the grad student that wrote the package you need is no longer maintaining it because they’ve graduated. Also the code they wrote sucks, but whatever.
I’m wary of software engineers coming over the bioinformatics because they never have the domain expertise required to make meaningful contributions, and yet many think they know everything.
getoffmycase commented on How the placenta evolved from an ancient virus (2020) whyy.org/segments/the-pla... · Posted by u/bkudria
If every part of a human coming from evolution, how it synchronize between each part? Is there any books explaining evolution in detail? How cell formed? How they found a way to multiply? How they choose DNA to store the information? And so on.
There is literally a world of biology (text)books that describe the process of evolution and how life came to be. I would recommend finding a syllabus at a local college for a biology class, getting the textbook second hand and then reading it
> “Tell me, Rand, what killed all these clicks?”
> I’m going to tell you every one of the major search, social, and content platforms has an incentive to keep you there. LinkedIn wants to keep you on LinkedIn. Twitter wants to keep you on Twitter.
Let me throw out another one. People have learned that they'll regret clicking. The incentive to get as many clicks as possible and no incentive to have anything there for them once they do click, except a bunch of in-your-face ads that make it impossible to read the "content", has perhaps made us all pause before clicking.