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cjbgkagh commented on How well does the money laundering control system work?   journals.uchicago.edu/doi... · Posted by u/PaulHoule
alwa · 3 days ago
Is that laundering or just retail drug sales?
cjbgkagh · 3 days ago
Money laundering, visa scams, and probably other criminal activity. The ones I noticed were in an airport so I doubt they were slinging drugs.
cjbgkagh commented on How well does the money laundering control system work?   journals.uchicago.edu/doi... · Posted by u/PaulHoule
imglorp · 3 days ago
I've come to realize that viewing the world through the simple lens of laundering causes dumb systems to suddenly make sense. Silly rabbit, you thought these industries were there for the normal public?

Gambling: https://www.cbc.ca/news/politics/online-gambling-sites-money...

Casinos themselves: https://www.ibtimes.com/political-capital/trumps-businesses-...

Commerce: https://www.wired.com/story/wired-awake-180518

Crypto: https://financialcrimeacademy.org/cryptocurrency-money-laund...

Shell companies: https://newrepublic.com/post/192244/trump-celebrates-destroy...

Real estate: https://www.firstaml.com/resources/5-ways-criminals-launder-...

cjbgkagh · 3 days ago
Overly expensive candy stores that only accept cash and have an excess of staff...
cjbgkagh commented on Say farewell to the AI bubble, and get ready for the crash   latimes.com/business/stor... · Posted by u/taimurkazmi
aydyn · 4 days ago
"Thought leader" isn't an actual title (or at least it shouldn't be). In my mind, its simply someone who you recognize as having the expertise worth paying attention to.
cjbgkagh · 4 days ago
It’s a title that is given to people to get them to present at junkets, a modern socially and legally acceptable way to bribe people. No one should take them seriously.
cjbgkagh commented on Gaussian Processes for Machine Learning (2006) [pdf]   gaussianprocess.org/gpml/... · Posted by u/susam
heinrichhartman · 4 days ago
Why would you learn Gaussian Processes today? Is there any application where they are still leading and have not been superseeded by Deep NNets?
cjbgkagh · 4 days ago
AFAIK state of the art is still a mix of new DNN and old school techniques. Things like parameter efficiency, data efficiency, runtime performance, and understandability would factor into the decision making process.
cjbgkagh commented on Living with Williams Syndrome, the 'opposite of autism' (2014)   bbc.com/news/health-26888... · Posted by u/colinprince
empressplay · 8 days ago
Despite having almost all of the prerequisite conditions (heart murmur, lazy eye, left-dominant, hernia, poor motor skills etc.) this was ruled out for me when I was a child due to exhibiting a high-IQ (~130), and I was repeatedly diagnosed with autism, despite being outgoing and high-EQ (and horribly naive!).

When I got older I began to develop connective tissue disorders and spasticity, which were incapacitating until I found treatment. I was diagnosed with EDS but that may also have been not-quite-correct, since apparently these issues are also common in WS.

Also, it apparently _is_ possible for people with WS to also have higher-than-average IQs. God, life is so frustrating sometimes!

cjbgkagh · 8 days ago
All your items on your list for WS is on my list for hEDS, add in the IQ and I’d say likely 2 TNXB SNPs, do a high quality WGS to be sure. Given the hEDS I highly doubt you have WS as well, just hEDS presents in a variety of depending on other co-occurring SNPs and you got a particular combo.

hEDS is far more common than currently thought because the medical diagnostics are not very sensitive, it’s a spectrum and what doctors tend to think of hEDS is the severe form of it.

cjbgkagh commented on Why F# could be the next mainstream programming language (2024)   blog.snork.dev/posts/why-... · Posted by u/smoothdeveloper
CrimsonCape · 16 days ago
I had a thought today, "when is Microsoft and/or Apple going to earnestly search out their next Steve Jobs?"

And I think the answer is that guys like Bill Gates and Tim Cook are too proud, too prideful to admit they are not kickass rockstars of tech, too jealous to find and cultivate their next super-figurehead. Instead they are safe and lame.

Microsoft needs a non-lame, non-MBA, engineer to take control and inject some younger mindset into making themselves cool again, focused back on tech, UI, user experience, and passion. Engineer tooling would be a great approach.

cjbgkagh · 16 days ago
That was supposed to be Scott Guthrie but he got pulled into the Azure whirlpool.
cjbgkagh commented on Ozempic shows anti-aging effects in trial   trial.medpath.com/news/5c... · Posted by u/amichail
alistairSH · 19 days ago
I've read (anecdotes from people in the fitness/body-building space) that the default dosing could be too high for many people. And the side-effects seem to ramp up with the dose.

IE, if you're getting weight loss at 1/2 the default dose, you might want to stay there, even if your MD wants you to increase to the default.

[default uses loosely here - people build up from a low dose over the span of weeks/months]

And the weight gain is due to a lack of lifestyle change. The drug just numbs your appetite, so you don't eat as much. If you go off the drug and return to over-eating, yep, you gain the weight back.

I also suspect many people lose the weight too fast and go too far. "Ozempic butt" is a joke for a reason - people loose a bunch of fat, but the massive calorie deficit also means they aren't exercising (no energy, and they probably weren't before the drug either), so they've probably crashed their metabolism.

cjbgkagh · 19 days ago
Very much the default is too high and the bro-science was indeed early on this. I’m super sensitive and had the bad negative reactions at 1/10th the starting dose. It’s been a wonder drug for me though, finally able to put my life back together after ME/CFS all but destroyed it.
cjbgkagh commented on Ozempic shows anti-aging effects in trial   trial.medpath.com/news/5c... · Posted by u/amichail
cjbgkagh · 19 days ago
Semaglutide is a signaling peptide, these are basically in a different class of medication that has traditionally been largely ignored. Partly due to difficulty defending patents for a class of medication that the body produces naturally, I.e. the instructions are in the DNA. Even if a drug company patents one GLP-1A they can’t patent all of them and any of them will work much the same way.

Because it’s a naturally occurring signaling peptide there already exist people who have too much of it and too little of it due to normal genetic variation.

cjbgkagh commented on Delta’s new AI-powered pricing strategy   blog.getjetback.com/delta... · Posted by u/bdev12345
darth_avocado · a month ago
You’d have to demonstrate that the pricing consistently is high/low based on one of the protected classes to successfully challenge it.
cjbgkagh · a month ago
I thought the bar was that you had to prove that it doesn't discriminate which a is much higher, I thought this is what drove many settlements.

Personally I would rather limit all price discriminations to a simple predictable and publicly inspectable customizable formulae. It's like the finance guys who exalt the virtues of increased liquidity but that disappears the moment you try to use it. Similar for the extra complexity for price discovery.

cjbgkagh commented on VPN use surges in UK as new online safety rules kick in   ft.com/content/356674b0-9... · Posted by u/mmarian
cs02rm0 · a month ago
The UK is becoming increasingly authoritarian in ways that feel increasingly antagonistic to the majority of the population, regardless of political party. Taxes are rising (with tax take falling), crimes are going unchecked, just mentioning increased immigration gets a lot of people's backs up, but as GDP per capita continues to stall and even fall, the pressure it puts on services is a factor for many. And we're seeing those with a few quid to rub together leave, but as long as those people leaving are straight, white males, or their families, they're being told "good riddance" regardless of the brain drain and loss of tax income.

On the NHS, I tried for years to push for improvements to switch to digital cancer screening invitations after they missed my mother (offering to build the software for free), which is now happening, but suggesting the NHS isn't perfect is against the religion here. My sister who works in NHS DEI hasn't spoken to me since publishing a book on it.

Every time someone with the finances, vision and ability leaves I think the situation gets a little bit worse, it increases the proportion of people remaining willing to put up with all of it. Anecdotally, many of my friends have already left, some of the older generation want to leave but feel tied in. My flight out is in 6 weeks. Good riddance, no doubt.

cjbgkagh · a month ago
This mirrors my experience of the UK. A dysfunctional country whose wheels were slowly falling off and now not so slowly. I’m generally pro devolution but in the UKs case their political class is so god awful that giving them more power didn’t seem to be a good idea.

I left for greener pastures a long time ago and subsequently all of my friends and anyone I knew of any talent has also left, it feels weird visiting a place I once called home and not being able to see friends.

u/cjbgkagh

KarmaCake day4813December 25, 2021
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