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Guzba commented on Aspartame aggravates atherosclerosis through insulin-triggered inflammation   sciencedirect.com/science... · Posted by u/teslabox
loeg · a year ago
Potato, potato. CICO is just physics, but "optimized flavor and marketing strategies" has had impact on the "CI" side of the equation.
Guzba · a year ago
It seems very different and critically important. Would we have a current obesity epidemic without "optimized flavor and marketing strategies"? Because if we would not, then that is the true cause and of fundamental public health importance.

If we would have an obesity epidemic even without "optimized flavor and marketing strategies", then it is totally irrelevant.

Guzba commented on Aspartame aggravates atherosclerosis through insulin-triggered inflammation   sciencedirect.com/science... · Posted by u/teslabox
ein0p · a year ago
It is, of course, not as easy as calories in / calories out, although the "Twinkies experiment" proved that you can in fact lose weight via caloric restriction alone. For any kind of "normal" diet insulin plays a massive role in obesity. And that bag of candy will absolutely send it to the stratosphere, especially if you consume sweets frequently. Buy a continuous glucose monitor (it's now available OTC via Stelo), and see for yourself. That's what I did.
Guzba · a year ago
I am aware of this, I am more trying to get those that really believe it is as simple as calories in calories out to break free from that Plato-ey over-simplified explanation.
Guzba commented on Aspartame aggravates atherosclerosis through insulin-triggered inflammation   sciencedirect.com/science... · Posted by u/teslabox
colingauvin · a year ago
This is an oversimplification.

>Does it matter if those calories are a prepackaged cake or candy? In the end it is just calories.

In the end it's a complex, poorly understood network of hormones and brain chemistry. Human action is mostly downstream of that.

Guzba · a year ago
I agree, however for some reason calories in calories out is generally unquestioned among people I know personally.
Guzba commented on Aspartame aggravates atherosclerosis through insulin-triggered inflammation   sciencedirect.com/science... · Posted by u/teslabox
alabastervlog · a year ago
Food got way, way cheaper, including and especially convenient (ready to eat) food. Plus a race between companies selling that food to optimize flavor and marketing strategies for maximum sales, which, at some point, had to start meaning “more eating”, not “more eating this instead of something else” otherwise line could not go up.
Guzba · a year ago
With this in mind, is the real cause "calories in, calories out" or "optimized flavor and marketing strategies"?
Guzba commented on Aspartame aggravates atherosclerosis through insulin-triggered inflammation   sciencedirect.com/science... · Posted by u/teslabox
nobodyandproud · a year ago
Food designed to circumvent the sensation of cloying or satiation.

Also, eating more in isolation and without talking.

Guzba · a year ago
Food design does seem like a higher potential explanation than many others offered.
Guzba commented on Aspartame aggravates atherosclerosis through insulin-triggered inflammation   sciencedirect.com/science... · Posted by u/teslabox
denkmoon · a year ago
The proportion of households with a person with time and energy to prepare a healthy home cooked meal has diminished. We have sacrificed domestic life on the altar of profit.
Guzba · a year ago
If healthy home cooked meals are better, why is that? This is a non-answer.

It must be something about the ingredients (invalidating calorie theory) or it must be lower calorie (invalidating ingredient theory).

Guzba commented on Aspartame aggravates atherosclerosis through insulin-triggered inflammation   sciencedirect.com/science... · Posted by u/teslabox
esskay · a year ago
> This just begs the next "why". Why are people eating more now?

Have you been in a US supermarket? It's absolutely nuts and I don't think many Americans realise it.

To be bombarded with monumentally huge portions of everything is just a recipe for...well....the situation the US is in. Theres not many other countries that have whole food groups focused on cramming in as much peanut butter, jelly, marshmallow, chocolate, or whatever other high fructose corn syrup crap is being used.

Massive slices of cake prepackaged and ready to eat? Yeah why not. 50 different coffee syrup flavors? Yeah go for it. How about a lovely massive bottle of sugary drink to wash it down? Just one? No no have a crate of 20 of the things.

Just for a comparison, look up candy on the Walmart site. Now do it on Tesco UK. Next, try the bakery, or hell even the meat isle, somehow the exact same product ends up being significantly worse for you in the US.

Guzba · a year ago
The orthodox reason for why people are overweight is calories in, calories out. Does it matter if those calories are a prepackaged cake or candy? In the end it is just calories.

Would gratuitously large steaks in the meat section and huge rotisserie turkeys instead of chicken at Costco produce the same result?

It seems strange to pick on certain types of foods unless believe those foods are the cause of obesity instead of just eating too many calories of any kind.

If you think cookies and candy are bad but other things are not, why? Is it that they are easier to over-eat? If so, how does that compound over time, given humans are trying to maintain homeostasis which includes a healthy set weight via satiety. Exercise induces more calorie consumption later. Over calorie consumption also induces lower consumption later. This seem like relevant factors.

Guzba commented on Aspartame aggravates atherosclerosis through insulin-triggered inflammation   sciencedirect.com/science... · Posted by u/teslabox
ein0p · a year ago
Here's why everyone is fat in the US: https://ourworldindata.org/grapher/daily-per-capita-caloric-...

It's not "aspartame". It's eating out twice as much as we did in early 70s [1], rise of fast food consumption, and huge portion sizes.

[1] https://www.ers.usda.gov/data-products/food-consumption-nutr...

Guzba · a year ago
This just begs the next "why". Why are people eating more now?

Such a significant behavior change across a large population is not well explained by "we just did".

I'm not sure fast food consumption or huge portion sizes is a great explanation. If fast food is the problem, why does that matter if it just comes down to calories? As for larger portion sizes, would even larger portions make us continue eating? Would tiny portion sizes make us all deadly malnourished?

Guzba commented on Microsoft is first to get HBM-juiced AMD CPUs   nextplatform.com/2024/11/... · Posted by u/rbanffy
tame3902 · a year ago
Yes, per core power consumption or better performance per Watt is usually more relevant than the total power consumption. And 1 high-core CPU is usually better than the same number of cores on multiple CPUs. (That is unless you are trying to maximize memory bandwidth per Watt.)

What I wanted to get at is that the pure core count can be misleading if you care about power consumption. If you don't and just look at performance, the current CPU generations are monsters. But if you care about performance/Watt, the improvement isn't that large. The Zen1 CPU I was talking about had a TDP of 180 W. So you get 6x as many cores, but the power consumption increases by 2.7x.

Guzba · a year ago
Makes sense, thanks for the good reply.
Guzba commented on Microsoft is first to get HBM-juiced AMD CPUs   nextplatform.com/2024/11/... · Posted by u/rbanffy
tame3902 · a year ago
Core counts have increased dramatically. The latest AMD server CPUs have up to 192 cores. The Zen1 top model had only 32 cores and that was already a lot compared to Intel. However, the power consumption has also increased: the current top model has a TDP of 500W.
Guzba · a year ago
Does absolute power consumption matter or would it not be better to focus on per-core power consumption? Eg running 6 32-core CPUs seems unlikely to be better than 1 192-core.

u/Guzba

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