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jlgreco · 13 years ago
I don't find this too hard to believe. Even today we see a push to either reformulate narcotic painkiller medications to make abuse difficult/impossible, or bundle them with acetaminophen/paracetamol. The problem is that when drugs like Oxycontin are reformulated to make abuse difficult ("Oxycontin OP") addicts are driven to attempt abuse of other narcotic painkillers which get them the desired affects... but with a potentially deadly dose of acetaminophen.

So instead of attempting to help these people while providing them with a safer alternative (methadone clinics exist, but for the most part they really are not targeted towards the middle-class/middle-aged prescription painkiller addict crowd), we are pushing to eliminate drugs that are safe to abuse. This move seems based in the plainly idiotic attitude of "well if an addict can't do something safely, he'll just give it up".

Cushman · 13 years ago
The thesis of the War on Drugs is pretty much that there are abstract, amorphous dangers to recreational drug use, and the proper role of government is to provide immediate, concrete dangers so that people will stop.

It does have a certain twisted logic to it, if you ignore every piece of empirical evidence generated over the last hundred years.

Mixing Tylenol with oxy is twisted in a different way, because it replaces an abstract danger (if you take some amount in some period of time, you might become dangerously dependent) with a somewhat less abstract danger (if you take some smaller amount in some shorter period of time, you might die).

venus · 13 years ago
In Australia we've had ads which specifically focus on the unsafe, illegal manufacturing conditions of a banned drug as a reason to avoid the drug. For example: http://3.bp.blogspot.com/-J1b1lX7HRxU/TlBbd9d4WHI/AAAAAAAAAN...

When I first saw this ad series I was stunned by the hollow, almost cynical reasoning on display, only to then be even more stunned by the lack of reaction in others. Your one-sentence summary of the War On Some Drugs, however, provides an insightful context to the campaign.

betterunix · 13 years ago
The thesis of the War on Drugs is that we can expand police power, persecute minorities with impunity, give hand-outs to well-connected industries (pharma, alcohol, tobacco, prison operators, etc.), and generally terrify the population into submission. There has never been any other goal, all the way back to cocaine first being made illegal a century ago.
jacquesm · 13 years ago
You're making a huge assumption here, which is that the central point of the war on drugs is actually to stop people using drugs.

http://en.wikipedia.org/wiki/Prison%E2%80%93industrial_compl...

smsm42 · 13 years ago
I guess the logic is not much different from the one used to burn people at the stake for their sins. If you smoke weed, it's bad for you, so we will put you in jail, which is 100 times worse, but at least your soul is cleansed by the government now.
rms · 13 years ago
Forcing oxycodone with acetaminophen has caused thousands of deaths. I recall reading a study that did the statistical analysis and got more precise numbers but can't find it with a five minute search.

In 2009, a federal advisor board recommended that Vicodin and Percocet be banned. Instead, they have to be reformulated to have about half as much acetaminophen. http://www.nytimes.com/2011/01/14/health/policy/14fda.html?_...

Suboxone prescribing physicians are more targeted towards the middle-class/middle-aged crowds.

ghayes · 13 years ago
This reminds me of the result of the abstinence argument. Namely, even if you believe all premarital sex is immoral, it's still important to realize that safe immoral sex is better for the man and woman than unsafe immoral sex. When the government forces what society believes to be "right," as opposed to what is effective (in regards to health, purse or morality), it can have harsh consequences.

[Edit: grammar]

adrianm · 13 years ago
I think you mean immoral. An amoral action is neither moral ("good") nor immoral ("bad").
pharrington · 13 years ago
Oxycontin OP is just Oxycontin in a "tamper-proof" pill. It only increases the effort needed to take a recreational dose; it doesn't increase the danger.

What you're talking about is a real problem, but you'd better pick a better example.

rdl · 13 years ago
Speaking of addicts/drugs/adulterants, what was the conclusion about levamisole in cocaine?
Symmetry · 13 years ago
Also, many of the FDA's objections to safer forms of Nicotine consumption are that less deaths might lead to more use.
cynicalkane · 13 years ago
Both things like Oxycontin OP and drug clinics seem like good ideas to me. I don't know why you seem to be saying it's one or the other and we're making the wrong choice. I don't think that's a valid representation of the decision space.
jlgreco · 13 years ago
Opiate abuse is damaging enough. Increasing the danger does nothing to slow abuse among the addicted and is incredibly unethical. It's like building a car that disables it's own airbags when you start speeding.

Worse actually. Speeding is not a physically addicting activity, merely psychologically addicting.

drivebyacct2 · 13 years ago
Because poisoning people as a way to get them to stop using drugs is abhorrent?
nazgulnarsil · 13 years ago
500 people die annually due to acetaminophen poisoning, mostly from attempting to take too many painkillers which include both opiates and acetaminophen. The acetaminophen is included for the express purpose of "dissuading abuse."
dhughes · 13 years ago
So many people I know in their 20s only use Tylenol and especially after drinking binges nobody I know uses Aspirin, zero.

Tylenol the worst thing to take with alcohol after binge drinking it's terribly hard on your liver.

It's worse for women who can't process ethanol ("alcohol") as well as men due to women's bodies producing less dehydrogenase which breaks down the ethanol.

From what I understand alcohol and acetaminophen (Tylenol) are processed by the liver in the same way so ingesting both overloads the liver, more so in women.

I think liver failure is going to be common in a few years in the 30-something crowd.

I'm not a doctor and not involved in any way in the medical field just a concerned citizen.

https://www.ncbi.nlm.nih.gov/pubmed/2248624http://www.health.harvard.edu/fhg/updates/overdoing-acetamin...

DanBC · 13 years ago
Liver failure is a concern in 30something crowds. Not from properly used paracetamol, which is a very safe effective med when used correctly. Certainly from paracetamol overdoses (which are easy to achieve) and also from excessive regular drinking. People have little idea how much alcohol they actually drink, nor how much they could drink safely.

The current understanding of paracetamol and alcohol is confused - some people think there may be a protective effect from the alcohol; other people think the combination may be more harmful than the sum of the paracetamol and alcohol; others think it's only a problem with pre-existing liver damage.

Aspirin is harmful to the stomach lining, and I personally would not like to take aspirin after heavy alcohol use.

(http://www.pharmweb.net/pwmirror/pwy/paracetamol/pharmwebpic...)

sliverstorm · 13 years ago
I can't speak for everyone, but I used Tylenol essentially out of habit as a young adult, because my parents gave me Tylenol as a child. This makes sense (I think), I am told aspirin should not be given to children.

So, it's probably just an education thing. Tylenol seems fine at what it does, and it isn't like people are misled. I bet you the label warns against mixing alcohol with Tylenol, and people really should know not to mix alcohol with other drugs.

lostlogin · 13 years ago
Speaking of aspirin, a friend had a headache last week, took some, and headache went away. He felt good, so went to his paintball game. You should see him a week later. He is basically yellow and purple.
Firehed · 13 years ago
Well, you can't deny that it does stop the abuse.

Really poor implementation though.

Tarential · 13 years ago
I have to weigh in here. It does not stop the abuse. Separating opiates from acetaminophen is extremely simple (look up cold water extraction). All it does is kill people who aren't aware of the danger or the alternatives.

There are many good reasons not to abuse oxycodone. The government doesn't need to add to the damage of people who are only hurting themselves.

jlgreco · 13 years ago
Abuse of prescription painkillers is massive. Acetaminophen does not prevent abuse, it only injures.
fulafel · 13 years ago
It's actually included because the combination has a synergistic pain killing effect.
neurotech1 · 13 years ago
Correct. There are times when you do want the anti-inflammatory properties of acetaminophen. Using only opioids for inflammatory pain, or muscle aches requires a higher dosage than if it was mixed with acetaminophen.

I usually take muscle relaxants (Soma) with Naproxen for back pain, and avoid the opioid pain meds or acetaminophen.

nazgulnarsil · 13 years ago
Yeah, that must be it, it's not like a doctor could possibly just say: "take aspirin with this."
Steko · 13 years ago
"mostly from attempting to take too many painkillers which include both opiates and acetaminophen"

Brief Google returns 31%. Still a large percentage but nothing like the number of people who die from prescription opiate abuse (the better part of 15K). Powerful drugs sometimes result in the death of user, news at 11.

[1] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874350/

jlgreco · 13 years ago
The danger posed by abusing narcotic painkillers is disputed by nobody. The issue being discussed here is the practice of making the abuse more dangerous to 'discourage' abuse.

I know it is hard for a lot of people to identify with drug users/addicts/fiends, so imagine we tried to apply the same sort of 'solution' to, say, speeding. Make all cars disable driver-side airbags once you go, say, 15% over the national speed limit. Speeding sometimes results in the death of the driver, news at 11.

How does that sit with you?

dhughes · 13 years ago
As a Canadian I laughed at "steep taxes" when I go to the US alcohol is ridiculously cheap and sometimes given out free (e.g. casinos).

Especially hard liquor and wine, I rarely drink but it's interesting to see such a huge difference: 6 pack $15, 1 liter Captain Morgan rum $40, Sauvignon Blanc wine $15

jlgreco · 13 years ago
Probably worth noting that prices and regulations vary wildly on a state-by-state basis.

In Pennsylvania all liquor and wine can only be purchased from state stores, and beer can only be purchased from licensed beer distributors (never grocery stores or the like, with very rare 'technicality' exceptions). (Restaurants and bars also sell beer, so in practice most people who buy beer in Pennsylvania will buy a six-pack from the local bar or restaurant, often at rather steep prices).

In Utah, chances are you won't be able to buy that same $15 six-pack of beer; alcohol content is limited to 3.2 ABV (very low, for those not versed) unless the establishment is also licensed to sell liquor.

Then you get into the whole local government regulations/taxes situation. There are hundreds of "dry counties" in the US where you simply cannot buy alcohol at all. "Blue Laws" seem to be more common than not, even in cities.

It's a complex situation. In some places in the US alcohol will flow like water (Such as Vegas, as you eluded to), but in other places alcohol laws will make Canada appear liberal in that respect.

dhughes · 13 years ago
Funny that you said Pennsylvania that's where I was and where I was thinking about when writing about cheap US booze.

I'm so used to government run liquor outlets I never even thought about it not being a private store.

adestefan · 13 years ago
And it's still done today. Denatured or methylated alcohol is a common product used around the world as a common solvent. Instead of using denatured alcohol to mix shellac I just get 190 proof grain alcohol since it's cheaper, but it's available in very few states.
monochromatic · 13 years ago
Where is grain alcohol cheaper than denatured?
sliverstorm · 13 years ago
That makes sense though. I think we generally agree as a country that we don't want to make alcohol freely availible to minors- so what do you do about industrial usage? Do you want to be carded to buy solvents? Should a teenager be prevented from buying solvents for painting?
forgottenpaswrd · 13 years ago
"I think we generally agree as a country that we don't want to make alcohol freely available to minors"

And this is one of your main problems as a country. When I was a kid in Spain I had access to as much alcohol as I wanted, so with all my family and friends and school partners (hundreds of people). We had very few problems with that, being a "borracho" was bad seen by society but moderate consumption was normal.

There is nothing wrong for a kid drinking some wine or Sider or Cava for lunch, in fact a lot of families continue giving their children access to low grade alcoholic drinks as it was done since the Romans(before water filtering 100 years ago drinking water alone meant death by water microorganisms).

Later they forbid it, and "botellon" appeared. It was cool to do something against the law, "borracho" was replace with "pedo" without the negative connotations, and our young people started drinking like there was not tomorrow.

lsc · 13 years ago
> I think we generally agree as a country that we don't want to make alcohol freely availible to minors

Hey kid; don't take the car out without my permission. And just in case you get any ideas while mom and I are out this weekend, I've rigged the brakes to fail 15 minutes after you start the car. Be good!

Man, I'm glad you ain't my daddy.

>Do you want to be carded to buy solvents? Should a teenager be prevented from buying solvents for painting?

Most places (in the sacramento area?.. I haven't bought spraypaint in a while.) card you when buying spraypaint. I have certainly been carded for buying solvents that one could potentially huff. It's certainly not as consistent or as well-enforced as alcohol, but it's done.

betterunix · 13 years ago
"I think we generally agree as a country that we don't want to make alcohol freely availible to minors"

Really? I was thinking more along the lines of "lower the drinking age and raise the driving age." I would rather see teenagers drinking than teenagers driving.

jws · 13 years ago
There is also a tax issue. You don't pay the spirits tax on yor solvents.
noibl · 13 years ago
Other [denaturing formulas] used bitter-tasting compounds that were less lethal, designed to make the alcohol taste so awful that it became undrinkable.

This approach was also applied to non-industrial alcohol products, leading to another round of mass poisoning:

http://en.wikipedia.org/wiki/Jamaica_ginger

monochromatic · 13 years ago
Except this poisoning was due to people trying to get around the government's required bitterant content.
betterunix · 13 years ago
Which bears an eerie resemblance to the problems we have with methamphetamine today. Much of the damage caused by methamphetamine abuse is the result of adulterants in the drug, which is produced under poorly controlled conditions. Pharmaceutical methamphetamine -- the kind that doctors sometimes prescribe to children -- causes far less damage to its users and even to those who abuse it (not to deny that abusing it is dangerous even without the adulterants).
gus_massa · 13 years ago
Previously submitted: http://news.ycombinator.com/item?id=1140603 (126 points, 2 years ago, 53 comments)
mtgx · 13 years ago
So who was punished in all of this? Let me guess - no one.
Deprogrammer9 · 13 years ago
They do a lot worse things to people today with advanced compounds.

Substances which will promote illogical thinking and impulsiveness to the point where the recipient would be discredited in public.

Substances which increase the efficiency of mentation and perception.

Materials which will cause the victim to age faster/slower in maturity. (WTF)

Materials will cause temporary/permanent brain damage and loss of memory.

http://en.wikipedia.org/wiki/Project_MKUltra

dandelany · 13 years ago
[Citation needed]. s/today/1973.
JoshuaDavid · 13 years ago
Did they find materials that cause the "victim" to age slower in maturity or increase the efficiency of perception and processing? Because if so, those seem unambiguously good (though the others seem pretty unambiguously bad).
Deprogrammer9 · 13 years ago
Is stunted development a good thing?