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thenerdhead · 2 years ago
The novel discoveries and technology advances for medical countermeasures is impressive since the pandemic.

It is very feasible we will see this happen alongside similar developments for SCV2 and other pathogens due to the precision and potency these strategies provide for broad lineages by targeting more conserved domains of the proteins.

I am especially interested in the delivery vehicle developments(nasal, patches, etc) and platforms that have been created to adapt quickly.

Exciting times.

idunnoman1222 · 2 years ago
The reason your immune system develops immunity to the bulb is that this is the part that presents itself. The stem is by its nature tucked away. I don’t see any reason to think that an immunity to this part of the flu virus would be effective.
the_real_cher · 2 years ago
If there is one thing the history of evolution has taught us it's that life will not be contained. Life breaks free, it expands to new territories and crashes through barriers, painfully, maybe even dangerously, but, uh... well, there it is.
snapcaster · 2 years ago
Good quote, but also reminded me how much I hate Ian Malcom
the_real_cher · 2 years ago
Why?
Cheer2171 · 2 years ago
Ok, so then we shouldn't even try to make vaccines? I don't know what your point is. We can't solve it completely, but there are still huge benefits.
xhkkffbf · 2 years ago
Long lasting? How will everyone in the chain profit if it's only dispensed once?

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onemoresoop · 2 years ago
Sounds great in theory. I just wonder whether when eventually catching a flu after not having one for a really long time the severity would be much worse.

I'd likely try this long lasting vaccine but I basically stopped taking the seasonal flu shots, they're hit and miss and too short lasting to bother.

beej71 · 2 years ago
"experimentally mutagenized the whole hemagglutinin"

Fuck, yeah, you did!

This would be awesome. I wonder if the shotgun approach works for COVID? I can get flu shots with no ill effects, but the COVID vax knocks me out for a day.

fwungy · 2 years ago
This on the news that the Astra Zeneca covid vaccine is being pulled due to Thrombosis deaths, i.e. blood clots.

I'm pro-vaccine and I'm waiting a long time before I try a new one. Let other people be the test subjects. I skip new to market pharmaceuticals for the same reason.

https://www.telegraph.co.uk/news/2024/05/07/astrazeneca-with...

Cheer2171 · 2 years ago
From the article you linked:

> AstraZeneca said the vaccine was being removed from markets for commercial reasons. It said the vaccine was no longer being manufactured or supplied, having been superseded by updated vaccines that tackle new variants.

The article you linked said there are about 100 "suspected" fatalities out of multiple millions of people who got the their vaccine.

fwungy · 2 years ago
They're pulling it because of the Thrombosis deaths. This is just PR cope from AZ. If that were the real reason they'd quietly discontinue manufacture.

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gradientsrneat · 2 years ago
iirc the Astra Zeneca COVID vaccines were less effective than the others because they used an older and more established method which is also widely used in flu vaccines, and also used in the COVID vaccines made in China/Russia. I would assume the issue is in Astra Zeneca's manufacturing process. My friend who follows virology closely also avoids that brand now.