> At the 3-day mark, I've hit a key milestone in cellular regeneration. My body has broken down old immune cells and generated new ones (Cheng et al., 2014).
There's now a number of studies on effects of fasting on chemo therapy patients, and they all make the same claim of regeneration through autophagy for some types of leukocytes.
It's not about just randomly breaking the cells, it's a normal process called autophagy where damaged cells are being recycled to be replaced by new ones. This happens all the time, but it seems that fasting can increase it significantly. The leukocyte count only temporarily falls, and then gets back to normal. This is extremely beneficial to chemo therapy patients because chemo damages cells, suppressing the immune system as a side-effect and also makes people feel very sick. This can reduce these effects.
I love how there are exactly zero technical details on the website about how this Basis thing works and what it is. It's chock-full of marketing copy and unnecessary animations instead. But from the early access form I can gather that it's going to have a monthly subscription (of course, it's 2021 after all) and probably need proprietary consumables.
I don't believe in these over-engineered 'quanitified self' solutions. Just get yourself a simple step counter and go for one or two walks a day and try to up the step count by a bit every time and don't eat like an asshole. It's worked for me for a long while now.
Man, it feels like you're taking a shot at me. I've averaged my 10k steps a day for almost a year now (actually averaged close to 11k in 2020 on a whole,but didn't get consistent until mid-March), and, while I have lost weight, I just can't get my diet under control. It's quite frustrating, honestly, and stems form my lack of desire to meal prep.
You don't have to meal prep per se, but I find having a plan helps. Buying and preparing food when you're hungry will make you eat more of the wrong stuff than if you had a plan.
I also found that by basically tripling my intake of vegetables helps a lot with feeling satiated. No one ever got fat because they ate too much broccoli, lettuce, and spinach.
About 8 years ago, I had a particularly stubborn stomach bug, that just would not go away. After a week I went back to the doctor, and he was reluctant to put me on anti-biotics incase it was viral, and also he was generally anti-anti-biotics if your immune system could do it on its own. So he had me do a 3 day fast. Only water, and once a day a small bottle of Gatorade. Day 1 was easy, day 2 was hard, day 3 was actually easy again. On day 4, I was told to reintroduce food slowly and to eat as close to unprocessed foods as possible, so I had a bowl of watermelon for breakfast, a cup of oatmeal for lunch, then for dinner... McDonalds.
The outcome was the bug did die, but I no idea if it was from the fasting or just that it had been 10 days. But the fasting wasn't that hard, and I felt better afterward.
The gatorade sounds horrendous, to dump a ton of sugar on you when fasting. It was probably for the electrolytes, a pinch of salt would have worked without all the junk in gatorade. And then you rarely need it on just a three day fast, only if you're dizzy. And if you're dizzy it means you've drunk too much water.
Glad you're better though!
Reddit fasting sub is ok to learn more, though they have some hangups like dry fasting.
I was just following the doctor's orders. I assume he wanted me to have caloric intake along with salt, but I'm not a doctor, I didn't question him, I don't know anything about fasting, and don't even know if it was necessary.
I've done a couple of 2 day fasts since then, just to see if I can still do it without much trouble, it gets harder as I get older.
A small bottle of Gatorade is 140 calories, I believe. Not nothing but also not too much to work through. Also you don’t have to chug it all in one gulp.
Why Gatorade... I assume for electrolyte? There are so many better alternatives. I had a serious electrolyte imbalance first time trying Keto diet. Took a potassium supplement and immediately got better.
1) If you are not eating for some extended period of time, your body starts to have deficit of not only glucose but also proteins which are then accquired from your own muscles. E.g you are not losing only weight but muscles too.
2) There are various types of immune system cells and they all have different lifespan. If your body detects new pathogen it start's to produce various new immune system cells to fight infection. For example: B-lymphocytes serves as "memory cells" for specific pathogens so it is required for them to live as long as they can.
What exactly are "old immune cells" then?
Thanks for answers :)
Your idea of continuous health monitoring is exactly what I'm searching for, like for years.
For the first problem, you need to ensure that you exercise the muscles along with fasting, to nudge the body away from salvaging proteins from muscle tissue. (Not a bio chemist either, this is what I have read in most articles about intermittent fasting)
I wonder what this "biosensor" is. There are several Glucose monitoring products out there however connecting them and retrieving data (for other purpose) is usually a non trivial task.
I'm also wondering about that. Abbott isn't known for making the raw CGM data easily available. Neither is Oura.
It might be possible via Google fit/ Apple health or via nightscout for the CGM devices, but the latter would imply some legal trouble. Maybe OP can clarify some details of how the integration works in this product.
Some non-invasive solutions for CGM devices are quite good already. I'd expect that the technology will be included in many higher-end health tracking devices within this decade.
Readit News
... if you were a mouse. Here's the article being referenced: https://pubmed.ncbi.nlm.nih.gov/24905167/
> I've hit a key milestone in cellular regeneration
What's key about it? In what way is it a milestone? What's the expected health impact in human patients?
Man, it feels like you're taking a shot at me. I've averaged my 10k steps a day for almost a year now (actually averaged close to 11k in 2020 on a whole,but didn't get consistent until mid-March), and, while I have lost weight, I just can't get my diet under control. It's quite frustrating, honestly, and stems form my lack of desire to meal prep.
I also found that by basically tripling my intake of vegetables helps a lot with feeling satiated. No one ever got fat because they ate too much broccoli, lettuce, and spinach.
About 8 years ago, I had a particularly stubborn stomach bug, that just would not go away. After a week I went back to the doctor, and he was reluctant to put me on anti-biotics incase it was viral, and also he was generally anti-anti-biotics if your immune system could do it on its own. So he had me do a 3 day fast. Only water, and once a day a small bottle of Gatorade. Day 1 was easy, day 2 was hard, day 3 was actually easy again. On day 4, I was told to reintroduce food slowly and to eat as close to unprocessed foods as possible, so I had a bowl of watermelon for breakfast, a cup of oatmeal for lunch, then for dinner... McDonalds.
The outcome was the bug did die, but I no idea if it was from the fasting or just that it had been 10 days. But the fasting wasn't that hard, and I felt better afterward.
Glad you're better though!
Reddit fasting sub is ok to learn more, though they have some hangups like dry fasting.
I've done a couple of 2 day fasts since then, just to see if I can still do it without much trouble, it gets harder as I get older.
1) If you are not eating for some extended period of time, your body starts to have deficit of not only glucose but also proteins which are then accquired from your own muscles. E.g you are not losing only weight but muscles too.
2) There are various types of immune system cells and they all have different lifespan. If your body detects new pathogen it start's to produce various new immune system cells to fight infection. For example: B-lymphocytes serves as "memory cells" for specific pathogens so it is required for them to live as long as they can. What exactly are "old immune cells" then?
Thanks for answers :) Your idea of continuous health monitoring is exactly what I'm searching for, like for years.
It might be possible via Google fit/ Apple health or via nightscout for the CGM devices, but the latter would imply some legal trouble. Maybe OP can clarify some details of how the integration works in this product.
Or you need bubble or miaomiao and again xdrip ;)
Adding a description of the setup that the author used would make the article much more substantial than it is now.
[0]: https://www.bbc.com/news/technology-46262520