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vedtopkar commented on Study shows most doctors endorsing drugs on X are paid to do so   medicalxpress.com/news/20... · Posted by u/peutetre
tonymet · 2 years ago
I'm confused that people have at the same time deep suspicion and also unwavering trust of drugs companies, depending on the story.

In most cases people are suspicious of pharma corruption & recklessness. Yet in a few contexts, for example with vaccines and psych meds , any criticism is deeply stigmatized. Critics are even slandered as backwards.

Why the paradox? I think a healthy dose of suspicion all around is warranted given their track record, plummeting healthfulness and the stakes at hand.

vedtopkar · 2 years ago
I think it's the difference between suspicion of the pharmaceutical vs the pharmaceutical company. You can criticize the company without criticizing the treatment.
vedtopkar commented on Study shows most doctors endorsing drugs on X are paid to do so   medicalxpress.com/news/20... · Posted by u/peutetre
killerdhmo · 2 years ago
Anyone have the actual paper? Does it list who (eg Huberman) is receiving the payola?
vedtopkar · 2 years ago
This seems to work: https://jamanetwork.com/journals/jama/fullarticle/2819356

Sadly no specifics about the 28 physicians they analyze.

vedtopkar commented on FDA considers first CRISPR gene editing treatment that may cure sickle cell   cnn.com/2023/10/31/health... · Posted by u/rntn
saulrh · 2 years ago
The cynic in me says that it was probably priced to cost exactly the same as the expected lifetime expense of treating of the disease.
vedtopkar · 2 years ago
In fact this is exactly how they set the price for these curative treatments. Gargantuan sums but hypothetically on average cheaper than the overall lifetime costs of living with the disease. Lots of recent debates on this in the world of Hepatitis C.
vedtopkar commented on Many researchers were not compliant with their published data sharing statement   jclinepi.com/article/S089... · Posted by u/miohtama
vedtopkar · 4 years ago
I'll echo that it's a tremendous amount of work to appropriately format data and metadata for upload to a public repository. It's not as simple as just mass uploading raw data files. It's no surprise that people skirt around this requirement when possible, especially as the size of files and number of samples per paper continues to balloon.

That's not to say that it's not important, but the labor required is vastly underappreciated. I say this as someone who has completed the task for many papers.

vedtopkar commented on Social media break improves mental health   bath.ac.uk/announcements/... · Posted by u/geox
vedtopkar · 4 years ago
Another anecdote: I felt my mental health declining from being sucked into "academic Twitter", which frequently devolves into unnecessary soapboxing in response to preprints or journal articles. I unfollowed all humans and now only follow institutional accounts. It really helped me.
vedtopkar commented on Evening use of light-emitting eReaders negatively affects sleep (2014)   pnas.org/doi/10.1073/pnas... · Posted by u/ivanvas
vedtopkar · 4 years ago
They speculate that the harmful component of e-readers is the blue-shifted illumination. I’d be curious if newer e-readers with temperature controllable backlights set to “warm” mitigates some of this sleep harm
vedtopkar commented on My lizard brain is no match for infinite scroll   alexanderell.is/posts/inf... · Posted by u/otras
vedtopkar · 4 years ago
It’s honestly so bad. No matter how hard I try, I find myself re-downloading TikTok or Reddit (Apollo) every month and then wasting away all my free time for a week or two before re-deleting them out of disgust. I truly don’t know what the solution is. I would just get rid of my smartphone if life wasn’t quite inconvenient without it.
vedtopkar commented on Ask HN: Alternate Email hosting to G Suite    · Posted by u/mrbonner
vedtopkar · 4 years ago
Curious as to why no one is recommending just paying for Google Workspace? $6/month for Google vs $5/month for Fastmail seems similar enough to avoid the hassle of transferring email servers.
vedtopkar commented on Researchers looking for mRNA were ridiculed by colleagues   macleans.ca/society/scien... · Posted by u/fortran77
vedtopkar · 5 years ago
I'm doing my PhD on topics related to mRNA and took a seminar class with Meselson in college. Really crazy how quickly our field has gone from obscure to mainstream this last year.
vedtopkar commented on The Mark Cuban Cost Plus Drug Company   costplusdrugs.com/... · Posted by u/yawnxyz
enchiridion · 5 years ago
That makes sense! This is where I feel like I have a disconnect between what I think applied science is and what it looks like in practice. It seems like they should know enough about the molecule, delivery vehicle, etc, to know that it will work the same. A medical "proof" if you will. I guess we're not quite there yet? Is there work pushing in this direction?
vedtopkar · 5 years ago
Sadly I don't know enough to give you a good answer. But I'm certain there are smart people working on it!

u/vedtopkar

KarmaCake day353September 1, 2012
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Stanford MD/PhD student and general programming enthusiast.

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