On guitar in fourths tuning, you only need to learn each interval and chord shape once, compared to multiple permutations in standard tuning. Not sure how much difference this makes over the long run as another poster pointed out, but for me it made the process seem much less overwhelming and motivated me to start learning how to make my own chord voicings, which is something I wouldn't have done in standard tuning.
> Not sure how much difference this makes over the long run
I tune in all fourths as well. For me it has made a huge difference since I made the jump some years ago. Putting voicings, patterns, etc., into muscular memory is faster and a lot less work. For my purposes, it makes the instrument more intuitive with a better ear-hand connection. Even very advanced players trip on the G-B strings oddity (with things like playing a fast, angular melody on different string sets, without preparation, for example).
If there is some Lisp package that has frequent updates that are not picked up via Quicklisp, and you want to keep up with those, then just put the tree of that thing in your project, and refer to its .asd file from yours.
I tune in all fourths as well. For me it has made a huge difference since I made the jump some years ago. Putting voicings, patterns, etc., into muscular memory is faster and a lot less work. For my purposes, it makes the instrument more intuitive with a better ear-hand connection. Even very advanced players trip on the G-B strings oddity (with things like playing a fast, angular melody on different string sets, without preparation, for example).