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patorjk commented on Being overweight overtakes tobacco smoking as the leading disease risk factor   scimex.org/newsfeed/being... · Posted by u/giuliomagnifico
apwell23 · 9 months ago
Thats interesting because I am healthy in other ways but my cholestrol has been high ( high ldl, total and high apob) . My trigs, a1c, bmi, homa insulin score ect are in line. No history of heart disease in either side of family.

My cardiologist has been asking me to get on statins for a while but i've been not able to convince myself to get on board to take a pill for the rest of my life.

patorjk · 9 months ago
There's something called a "lean mass hyper responder", it's a type of person with high LDL but they're still healthy. You may fall into that category. However, high apob is more correlated to heart disease than high LDL. A lot of the online doctors who say high LDL isn't bad are saying that because some people have large LDL particles, and it's apparently the number of particles that's the problem, not the amount of LDL cholesterol.

I've dug into this topic a lot sense there's a lot of heart disease in my family. I've found that eating a bowl of oatmeal once a day reduces my LDL under 130 (I've been taking quarterly cholesterol blood tests to keep an eye on things). It's probably the fiber content that's doing the work, but I haven't tried other high fiber foods yet. However, I'm not a doctor so make of this what you will.

patorjk commented on Being overweight overtakes tobacco smoking as the leading disease risk factor   scimex.org/newsfeed/being... · Posted by u/giuliomagnifico
bwestergard · 9 months ago
This paper provides a helpful breakdown of types of mortalities and how they're associated with BMI. It's interesting to see that the lowest All-cause mortality is at a BMI of 25. A BMI of 30 doesn't increase the hazard ratio that much, but a BMI of ~45 doubles it. The minimum for cancer mortality is notably lower (21) but perhaps surprisingly the minimum communicable disease mortality is at a BMI of 26.

https://www.thelancet.com/journals/landia/article/PIIS2213-8...

patorjk · 9 months ago
This kind of stat is misleading and is seen in many health metrics - blood pressure, cholesterol, etc. In fact, it's sometimes known as the "cholesterol paradox" because people with higher cholesterol have a lower risk of dying. However, it's misleading because blood pressure, weight, and cholesterol often come down as people suffer from chronic disease or malnutrition. The chronic diseases people get are often from their weight, blood pressure and cholesterol, and when this is corrected for, the all-cause mortality curves better reflect what a healthy person's numbers should be. So in reality the lowest point of the all-cause mortality curve for BMI is below 25. 25 is not optimal.

Dr. Carvalho recently made a video on this topic (he even mentions the BMI curve). You can watch it here: https://www.youtube.com/watch?v=n4h135SBebc

patorjk commented on Should You Be Rinsing Your Plates Before Loading the Dishwasher?   allrecipes.com/should-you... · Posted by u/thelastgallon
patorjk · a year ago
I've heard people say you don't need to rinse, but from experience this just doesn't seem to be true, or at least it's based on the dishwasher you have. I had a dishwasher 15 years ago where I tested the idea of not rinsing vs rising, and if I didn't rinse, I would sometimes have dishes that weren't completely clean (ie, hot chocolate residue in a mug, cheese from mac n cheese on silverware, etc).
patorjk commented on YouTube now blocking ad block   old.reddit.com/r/youtube/... · Posted by u/epa
patorjk · 2 years ago
For a few days I was getting the prompts and finally the 3 video warning. I went without youtube for a few days, when I tried yesterday my AdBlocker was working fine on it. I watched several videos and got no warnings. It's unclear to me if they gave up, or if they're testing this in waves to see what happens.
patorjk commented on Ask HN: Has anyone gotten complete, permanent relief from tinnitus?    · Posted by u/actinium226
patorjk · 2 years ago
I've had tinnitus for around 15 years now. I've followed the research pretty closely. One thing to be especially weary about is the placebo effect. For some reason it's especially bad when it comes to tinnitus. I think that's how so many snake oil products can thrive in this area.

Back when they were doing the OTO-313 study a year or so ago, I read several reports from people who were in the study the drug had made their tinnitus go away (one on the TinniusTalk forums, and a few in a tinnitus Facebook group). However, when the results came back, the drug did not beat placebo. A similar thing happened with the FX-322 drug (that one was for hearing restoration but people were hopeful it could address tinnitus too).

patorjk commented on Ask HN: Has anyone gotten complete, permanent relief from tinnitus?    · Posted by u/actinium226
infecto · 2 years ago
The only resource on the internet to read/discuss it. http://tinnitustalk.com

Everything else is full of people saying they are going to go crazy.

My opinion is to approach it that it cannot be cured and is a part of life. I got it around 2016, unknown reasons why, at the time my hearing tested normal for my age. Have seen doctors over the years and while I know its potentially a symptom of something else, I don't know what that something else is.

The first few years were brutal, reading online does not help as people talking about going crazy. The best approach is to ignore all that and just accept it. Mine not be that terrible, but it is always there but it no longer bothers me. Sometimes I do get some weird flare ups where it pulsates but overall its just part of my life. The sooner you accept that the better.

patorjk · 2 years ago
I second this resource. Lots of good threads and discussion here. The forums are full of threads where people talk about things they've tried.
patorjk commented on Microsoft to kill off VBScript in Windows to block malware delivery   bleepingcomputer.com/news... · Posted by u/rmason
patorjk · 2 years ago
As an intern 20 years ago I wrote a lot of VBScript code to automate the generation of a bunch of Excel reports. I ran into my old boss 10-12 years ago and he said the scripts were still humming along. I've sometimes wondered how long those scripts would last, I guess they're end of life is coming up (if they haven't been rewritten by a new intern already).
patorjk commented on Men Without Work (2016)   time.com/4504004/men-with... · Posted by u/ianai
asperous · 3 years ago
I wrote the original wikipedia article for this! I haven't read the book just thought it was notable.

It was a little tough getting past the editors (the section referencing all those news articles they made me put in to reach notability). I also got called a shill for the publisher.

patorjk · 3 years ago
I don't understand why some people feel the need to be so snarky in their summary messages:

> I'll bet this clown got paid to write this article and they did a poor job of it, too.

It's really turned me off from contributing. Years ago I got into a spat where someone didn't like something I added to an article and said my sources weren't valid since they were blog posts. I went and found a mainstream magazine article on the topic and they still balked - but eventually relented since they really didn't have a leg to stand on. They silently removed the addition a few months later. However, at that point I was over it and didn't care. The fact eventually made it back into the article a few years later when someone else added it in.

patorjk commented on Honey consumption improves blood sugar and cholesterol levels, study suggests   sci.news/medicine/honey-c... · Posted by u/WaitWaitWha
WaitWaitWha · 3 years ago
Research paper for the basis of the article [0]

[0]: https://academic.oup.com/nutritionreviews/advance-article/do...

patorjk · 3 years ago
I wonder if the submitted link should be changed to your link. I can access your link fine but I get an error when I try to access the submitted link.

u/patorjk

KarmaCake day1402September 24, 2010
About
Programmer and amateur photographer (patrickgillespie.com, https://www.flickr.com/people/40423570@N07/, instagram.com/patorjk).

I also have a website - patorjk.com - though it's not updated much anymore.

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