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maivjj commented on Sorry, Mad Men. The Ad Revolution Is Here   wsj.com/business/media/ad... · Posted by u/marban
maivjj · 9 months ago
Both the creatives in media (all forms - ads, news, sports, movies, radio, tv, games etc) and the ad tech crowd don't talk about barely growing global disposable income. Meanwhile they are furiously producing more and more content (ie real estate for ads).

What happens when production outpaces consumption or supply over shoots demand? Naturally hiring will slow, mergers and consolidation, cost cutting via relying on tech and more automation.

We have sort of peaked in how much people's Attention can be milked. In both time and cash. They just don't like talking about it.

maivjj commented on Ask HN: How do you pick between different OpenAI LLMs?    · Posted by u/endorphine
maivjj · 9 months ago
The diff only matters if you are relying on them 24x7 to generate revenue in your own daily business or something. For generic infrequent questions, it doesn't matter much.
maivjj commented on Hypothalamic deep brain stimulation augments walking after spinal cord injury   nature.com/articles/s4159... · Posted by u/Jimmc414
Jimmc414 · 9 months ago
The researchers built a map of brain activity and discovered that neurons in the lateral part of the hypothalamus were highly involved in recovery of walking function. focusing on the hypothalamus they found a new “command center' that can help restore movement when the usual direct routes are disrupted.

It's wild.

First they let animals with spinal cord injuries attempt to walk on a treadmill. At different stages of recovery they checked which neurons were active

Then they injected viruses into the spinal cord that move backward along nerve pathways up into the brain. By seeing exactly which brain cells the virus ended up in they could figure out which neurons in the brain directly connect to the spinal cord segments controlling the legs.

To analyze the entire brain at once they used tissue “clearing” techniques that make the brain transparent. They then used specialized microscopes to scan and reconstruct the brain in 3D.

They wrote algorithms to align these images to a brain map so they could count active, spinal cord connected neurons in precise brain regions.

Combining these markers connectivity tracers and 3D imaging they created a complete atlas of which brain cells became engaged during walking recovery. This approach highlighted the lateral hypothalamus as a site that sends signals down to the spinal cord to help restore walking function even when the usual direct routes are damaged.

maivjj · 9 months ago
Wow! What a process. Thanks for the explanation.
maivjj commented on Ask HN: Do you believe we are in a particularly chaotic time period?    · Posted by u/bloomingkales
maivjj · 9 months ago
Having faced some personal chaos in life I don't think its more or less chaotic.

Its just the information overload environment produces more triggers. Reduce news and social media off consumption and it feels much less chaotic.

Info overload especially constantly looking at problems above the pay grade/skill level are just going to screw with the head.

Think about your first job, did you try to understand or solve everything the team faced when there was chaos? Initially you might try, but over time you settle into a role where you fit and tune other things out.

These days whenever I feel the urge go down some social media/news generated rabbit hole, I just open Khan Academy or ChatGPT and start talking/looking up some solved problem. Not the unsolvable stuff. It turns out more satisfying than consuming news or social media stuff. Other option is a good game. Changes my mood a lot.

maivjj commented on Hypothalamic deep brain stimulation augments walking after spinal cord injury   nature.com/articles/s4159... · Posted by u/Jimmc414
maivjj · 9 months ago
Why did they choose Hypothalamus? I vaguely remember being taught it controlled temperature regulation.

u/maivjj

KarmaCake day14December 11, 2024View Original