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leaf_house commented on The human genome is full of viruses   medium.com/medical-myths-... · Posted by u/olalonde
sudoaza · 6 years ago
Huh, can we remove those? isn't there a cost to have all those extra sequences lying around?
leaf_house · 6 years ago
There is a cost in terms of energy required to replicate the genome. The cost is relatively small though and grows slowly within the population so it is subject to fairly weak selection. On the other hand deleting DNA is always quite a risky proposition.
leaf_house commented on Mozilla lays off 70   techcrunch.com/2020/01/15... · Posted by u/ameshkov
bscphil · 6 years ago
Eh.

> the remaining 56 percent make more than $45,000 per year

So the median is more than $45k. I would say the difference between $31k and $45k is pretty significant, at least depending on where you live. In San Francisco that would likely not be enough for someone to live comfortably alone.

leaf_house · 6 years ago
Sure but you can live plenty comfortably on 100k. I don’t think we would be having this conversation if she was making that.
leaf_house commented on The most important scientific problems have yet to be solved (1897)   thereader.mitpress.mit.ed... · Posted by u/anarbadalov
AareyBaba · 6 years ago
We know that life is evolvable because life exists and we know the biochemical mechanisms involved (DNA + cellular biochemistry).

Evolution implies a relatively smooth path through "DNA space" from, say for example, an early single cell eukaryote to a mushroom. However the search space is enormous. Even if we account for billions of years of evolution and a trillions of evolutionary experiments each year, a simple random walk with selection through DNA space should go nowhere because of the numbers involved. The curse of dimensionality[0] means there has to be some other principle of nature to make the search space yield a path from one viable life form to another. The search space of life would have to be 'smooth' in some sense. That 'smoothness' is something we don't understand.

If DNA space is just 256 bits (as a dramatic simplification), then 2^256 is a very very big space to search just by chance [1]. Now imagine a space orders of magnitude bigger.

[0] https://en.wikipedia.org/wiki/Curse_of_dimensionality

[1] https://youtu.be/S9JGmA5_unY?t=22 (3Blue1Browns wonderful illustration of how large 2^256 is)

leaf_house · 6 years ago
Comparing evolution to a random walk with selection doesn’t quite sit right with me. In practice much of evolution occurs via gene duplication and recombination. At that point you can evolve complex changes very quickly. Evolving novel phenotypes is much easier if your starting material is an existing functional gene. Many motifs can be reused and reapplied.

Comparing a mule with it’s parents shows how much novelty can be produced in a single generation (in this case an evolutionary dead-end of course)

leaf_house commented on Linux Mint's Sobering Update: A Glimpse into the Personal Struggles Devs Face   forbes.com/sites/jasoneva... · Posted by u/abeger
tannhaeuser · 6 years ago
Cambrian explosion? The main distros (Debian/Ubuntu, RH/Centos, Arch, Mint, Gentoo, Suse, Slackware) haven't changed in like ten years or more, the only relatively recent additions being the Devuan branch of Debian, and Alpine. Or have I overlooked something?
leaf_house · 6 years ago
Elementary OS, Void Linux, Deepin, Antergos and Tails are a few notable ones off the top of my head. Void has been around for a minute but has become a lot more popular recently.
leaf_house commented on Penguin travels every year to visit man who rescued him (2016)   cbc.ca/news/trending/dind... · Posted by u/colinprince
majani · 7 years ago
Even in the growing and harvesting of plants, large amounts of animals get killed in the process. The moles underground, the rabbits and hares that eat the plants, the rats and snakes that shelter in the piles of harvest etc, they all have to be killed en masse to ensure a good harvest. Given this fact, veganism appears to me like a refusal to accept the reality that this world is a harsh one full of chaos. I prefer to focus on sustainable consumption as the reasonable balance between the two extremes of veganism and American fast food.
leaf_house · 7 years ago
This is a common logical fallacy used to justify your current lifestyle. Veganism is not about moral purity, its about the tangible impact of your actions.
leaf_house commented on Penguin travels every year to visit man who rescued him (2016)   cbc.ca/news/trending/dind... · Posted by u/colinprince
agumonkey · 7 years ago
Not what I was saying. Eating meat is natural, it's been for cosmic ages, and to an extent I have no issue with that. The mass globalized consumption does bother me. I reduce my consumption. I might try vegan but I'll surely miss all the meat based products. Maybe I'll find a middle point by breeding, killing producing it myself so at least I did it on my own, think what you want, there's a form of respect in that. I don't think I will enjoy 100% vegan. Another option is synthetic meat, we'll see.
leaf_house · 7 years ago
Why not set yourself the challenge of only eating ethically farmed animal products? I think you’d find this ends up leading to a mostly vegan lifestyle unless you’re willing to devote considerable time and money.
leaf_house commented on Meat-free 'Impossible Burger 2.0' tastes even closer to the real deal   engadget.com/2019/01/07/i... · Posted by u/alangpierce
danharaj · 7 years ago
That's really cool. Although I wish there were more vegan food that didn't try to replicate non-vegan textures and flavors. Imitation can only be playing catch-up. The best vegan and vegetarian food does its own thing.
leaf_house · 7 years ago
Just out of curiosity, are you vegan/veg? I hear this point of view a lot online but I’ve rarely heard it within the vegan community where people are usually pretty honest about craving junk food/burgers etc every now and again. Not trying to call you out, genuinely curious.
leaf_house commented on Surprise DNA Results Are Turning Customer-Service Reps into Therapists   bloomberg.com/news/featur... · Posted by u/laurex
azinman2 · 7 years ago
Saying “this is science” alone as an answer to the validity is really doing science a disfavor. Not only are these consumer grade tests, but there’s been a lot of evidence of the fallibility of DNA testing (particularly for crime scene analysis) in recent years, let alone the fact that everything they show is based on models that are constantly updated and effectively best guesses. I really wish they’d be more upfront but it’d probably be too big a challenge to sweeping in new customers.
leaf_house · 7 years ago
Relatedness testing is pretty trivial with modern chip/sequencing tech so this stuff does actually tend to be pretty cut and dry. The big worry is sample swaps but those should hopefully be the exception and not the rule.

u/leaf_house

KarmaCake day16January 1, 2019View Original