Sadly, it's not a complete solution as some harmful substances bio-accumulate in other tissues. A benefit may be had regardless as some substances leach back into the blood if the concentration gradient is sufficient.
I just don't see it happening. They cost too much and take too long. Not holding my breath here.
However there have been some efforts last year or two to break the security. I remember reading about some exploit some time ago that would work from the original Xbox One to the current Series X devices though it relied on some program on the store that it was removed. However (supposedly, i do not own an Xbox One) the files were archived and one is still able to modify and compile the program (so it wont be caught by whatever automation MS has), use dev mode to put it on the store or device, then use that to apply the exploit.
I expect the Xbox One (and later) to be cracked open pretty much as soon as Microsoft abandons the whole thing as recently their interest in Xbox seems to be waning.