Readit NewsHow do you measure those?
- In mice.
- Tested 16:8 pattern.
- Sustained consistently for nine weeks.
- No exploration in this study of the effects and/or benefits from the gene expression.
N=1 but I've been doing ~16:8-ish along with strict keto for the past five years and the net benefits for me have been transformative in fitness (Weight: -100+ lbs, BMI: Obese->Fit), long-term health (A1C, LDL/HDL, Trigs, BP, resting heart rate all from bad to great), cognitive acuity and emotional stability. First 12 weeks required serious effort/focus to transition habits, palette and metabolism (must RTFM and be rigorous) but after that it's been surprisingly easy to sustain long-term, requiring no will power or conscious effort.
Other surprising experiential learnings: Dietary intake impacts long-term mental/emotional states FAR more than I ever suspected. Food & taste prefs I had since childhood are not innate. Many things I loved no longer even taste good. Hunger pangs and cravings are driven by my blood sugar cycle. Once I stabilized that I no longer get hungry or feel food deprived/obsessed. (<--- all N=1 of course.)
I do quite a bit of high intensity cardio (cycling) + weight training and my recovery and peak performance suffered a lot when I tried keto for a few weeks, it also tanked my hormone levels. I still focus my carb intake on times around training but generally don't restrict.
Going to try to get a few more years out of it hopefully until Imagination Tech's hardware accelerated ray tracing solutions can make it to Apple's GPUs.
The only thing a workout has ever made me feel is sore and tired. Light or heavy, long or short, cardio or strength. Doesn't matter, that only changes how sore and how tired I am after, and how long those feelings last.
I'd exercise way more if I ever felt "energetic and rejuvenated" after a workout. The only thing keeping me doing it is knowing how critically important it is to me long term cardiovascular health.
Some context: I'm overweight and could definitely stand to be more active. But I do value exercise and a couple of months ago started going to fitness classes, have played sports casually but regularly in the past, used to regularly go to a gym, and have dabbled with a few different kinds of home workout, including running. The game aspect of sport is fun, but the physical activity involved still only left me sore and tired.
It's good to know that I'm not the only one, it's a bit sad to know that there doesn't seem to be anything I can do about it.
Not sure you should see it so negatively/defeatist. Maybe you just have not found the right thing yet that gives you joy. I discovered my love for road cycling only in my mid thirties and now derive immense pleasure from long rides totally exerting myself and burning 2000+ calories in many of those rides. Lost 10kg of weight and am fitter at 40 then I ever was before.
We moved back to NL and have 1GBit fiber, and there has been a short outage once in three years. I know that there are a still a lot of addresses without fiber, but when I last checked the stats, about 50% of the addresses has the possibility to get a fiber subscription. Heck, even my parents who live in a small rural town have fiber.
MKBHD recently did a pretty good video exactly on this type of question: https://www.youtube.com/watch?v=w2KbwC-s7pY