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jbotz commented on Size of Life   neal.fun/size-of-life/... · Posted by u/eatonphil
sungho_ · 8 days ago
What surprised me most was how large a single neuron is.
jbotz · 8 days ago
In generalized, abstract sort of way it's probably accurate, but in reality most neurons don't look much like that and many have dendrites orders of magnitude longer than the one in that image. Stringing all your dendrites end-to-end they can probably easily go to the moon and back.
jbotz commented on We're learning more about what Vitamin D does   technologyreview.com/2025... · Posted by u/Brajeshwar
kjkjadksj · 18 days ago
It is what killed Bob Marley
jbotz · 18 days ago
Not all skin cancers are caused by UV exposure, and in particular acral lentiginous melanoma, which is what killed Bob Marley, almost certainly never is.
jbotz commented on Intercellular communication in the brain through a dendritic nanotubular network   science.org/doi/10.1126/s... · Posted by u/marshfram
api · 2 months ago
I still think there's a good chance that evolution has figured out some way to leverage quantum computation, probably in a very different way from the way we're trying to do it with ultra-cold low noise quantum digital circuits. If this is the case it's going to be some kind of high temperature noisy analog stochastic way of harnessing QC. The phrase "stochastic analog quantum computer" comes to mind.

It's how little energy the brain uses, especially for learning. The brain seems to be hundreds of thousands to millions of times more energy efficient than any kind of current AI on a classical computer, not to mention still beating it in terms of performance and versatility. Transistors do not use millions of times more energy than synapses, and processor feature sizes are not millions of times larger. Something else is going on.

Either the brain is leveraging QC or our AI training algorithms are just really really horrible compared to whatever is happening in biology. Maybe biology found learning methods that work thousands of times better than differential backpropagation.

jbotz · 2 months ago
> The [human] brain seems to be hundreds of thousands to millions of times more energy efficient than any kind of current AI

I don't know about that... I've consumed quite a few calories in my lifetime directly, plus there is all the energy needed for me to live in a modern civilization and make the source material available to me for learning (schools, libraries, internet) and I still only have a minuscule fraction of the information in my head that a modern LLM does after a few months of training.

Translated into KWh, I've used very roughly 50,000 KWh just in terms of food calories... but a modern human uses between 20x and 200x as much energy in supporting infrastructure than the food calories they consume, so we're at about 1 to 10 GWh, which according to GPT5 is in the ballpark for what it took to train GPT3 or GPT4... GPT5 itself needing about 25x to 30x as much energy to train... certainly not 100s of thousands to millions of times as much. And again, these LLMs have a lot more information encoded into them available for nearly instant response than even the smartest human does, so we're not really comparing apples with apples here.

In short, while I wouldn't rule out that the brain uses quantum effects somehow, I don't think there's any spectacular energy-efficiency there to bolster that argument.

jbotz commented on Beetroot juice lowers blood pressure by changing oral microbiome: study   news.exeter.ac.uk/faculty... · Posted by u/lightlyused
pinkmuffinere · 5 months ago
Do we know the mechanism by which this works? Is it just anecdotal, or is this studied at a population/statistical level?
jbotz · 5 months ago
I see everybody talking about the nitrate, but there is another substance in beets that might be relevant... betaine, also known as trimethylglycine HCL. I take about 800mg of this pure in my orange juice in the mornings and it gives me a very noticeable boost. But it is possible that this effect is specific to me and maybe other people who are "under-methylators" (which I think is a somewhat pseudo-scientific concept, but it led me to try betaine and I got results).

Betaine was first isolated from beets, hence the name, and as the other name, trimethylglycine, hints it has 3 easily donated methyl groups, so if you do need those for some reason it may be useful to you. It's also pretty cheap and unlikely to be harmful.

Edit: I found this... https://www.strongerbyscience.com/betaine/

u/jbotz

KarmaCake day3128January 2, 2017
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