Cronenberg made The Fly in Hollywood, and I think it's it's great, but he wasn't able to get much more than that on the go, even though he came close to landing several high profile gigs.
In some alternate history timeline Cronenberg's name would have been attached to several big time Hollywood properties, and the world would be mostly the same just a little bit grosser. Of course, I'm happy with Cronenberg's mostly Canadian produced oeuvre the way it is, I just like to wonder.
I also used to wonder what the world would look like if Lynch has directed ROTJ, but I came to realize it was a ridiculous premise, Lynch needed far more creative elbow room than what the 3rd instalment of an established franchise could possibly afford, and there was no chance Lynch would ever agree to such a thing. So we got Dune instead and I'm happy with that too.
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While I know it's a marketing term, I think a good distinction is that agents have a loop in the execution graph, and can choose whether to loop or keep going. Workflows are chained LLM calls where the LLM has no "choice".