hn19128ks8 (u/hn19128ks8)

canttestthis · 6 years ago

Tangentially I'm interested to know whether taking melatonin for long periods of time (years) reduces its effectiveness. I've been taking it for nearly a year but I've heard stories about how you need to keep increasing the dose to get the same effect.

hn19128ks8 · 6 years ago

Anecdotally, I am taking it for years and haven't noticed any reduced effectiveness. Effectiveness increased when I reduced the dose to 0.3 mg. and started taking it several hours before sleep. https://slatestarcodex.com/2018/07/10/melatonin-much-more-th... is pretty much a required reading on melatonin, as well as https://www.gwern.net/Melatonin. Neither discuss tolerance at length unfortunately.

pbreit · 7 years ago

Unpopular opinion: I don’t like this. Would much prefer that ideas compete. Id sort of give Amazon a pass since, unlike twitter, Reddit, Facebook & YouTube, it doesn’t make many promises regarding the free exchange of ideas. But still.

hn19128ks8 · 7 years ago

Today in 1985 Amazon pulls all videos discussing links between H.pylori and ulcers from its Prime platform. Many HN users laud the decision to remove the content that a "scientific consensus" of the medical community have "proven false".

'This is not about competing markets of ideas', the HN users are saying, "these are real doctors -- real scientists -- saying that the 'facts' in these videos cannot possibly be true. Therefore these are 'false facts' and should be removed."

https://www.cdc.gov/ulcer/history.htm