With a keylogger, you lose passwords you typed in since the keylogger was installed, but that is rarely all of your passwords.
Most of these managers support some form of 2fa. I use a yubikey with mine such that if my master password is compromised someone would still need to obtain my security key. You can enroll multiple and keep one in a safe and one or more on your person. It's not perfect, but it prevents the vast majority of huge dragnet style malware attacks and a lot of the targeted ones until you get to the point where someone is trying to hunt you down on the street.
This still leaves a case where someone manages to get the final key out of memory but you're pretty hosed at that point anyway. I'd prefer a system where the yubikey itself is doing the final credential decryption instead of the CPU, unfortunately most people aren't that paranoid though.
Also, if you're struggling with getting things done because you're always dopamine seeking, get checked for ADHD. There are some extremely effective treatments that can make your life way easier if that turns out to be the problem.