A somewhat recent paper:
Systematic review and meta-analysis of antioxidants with or without exercise training improving muscle condition in older adults
https://pmc.ncbi.nlm.nih.gov/articles/PMC12491480/
Seems to imply that as we get older, antioxidants might help the body recover from exercise. More specifically, antioxidants may help resolve exercise induced inflammation in adults aged over 55 years.
So it seems that, yes, as you get older, its easier for the body to wear down, but this can be mitigated somewhat.
A couple decades ago, I stopped running on concrete or asphalt, and took up trail running, i.e. running on (mostly) dirt. It feels way easier than running on asphalt, much less on concrete. If you're skeptical that running on concrete or asphalt feels harder, give it a try. YMMV, but I'd bet you notice a difference.
And yes, I do fall sometimes, tripping over roots or rocks. But I recover quickly.
I read a book my Michael Colgan at the time, and he mentioned training athletes on the trails as much as possible to reduce injury, so I gave it a try ...
That was 25+ years ago. At first people looked at me strange, like I was running from an animal. But its common now, and I'm still running on the trail, and knees seem OK.
Yes of course, you can still trip, step on a snake, etc, but its a different kind of injury. You are adapting gait and balance constantly which is nice too.
Running on the trail is much more interesting, with constant change, ups, downs, variations. Whereas running on grass / asphalt I can go into autopilot mentally and start ruminating, this is harder on the trail and I am more in a state of "here and now".
You may also find this interesting:
"NRF2 activation is a predictor of poor clinical outcomes in lung cancer. Given the widespread use of NRF2-inducing compounds such as resveratrol and sulforaphane, these findings raise important concerns about their safety in individuals at risk for or living with cancer."
https://link.springer.com/article/10.1007/s11357-025-01736-0
Many people eat high-sulforaphane containing foods for health benefits.
And finally from last week https://newatlas.com/diet-nutrition/vitamin-c-air-pollution-...
This was about 1000mg / day for humans.
The user metrics in O'reilly (and probably most learning apps) has floored in the last 12 months. I see they've launched a new AI platform now. They're definitely going in a direction - time will tell if it's the right one.
Personally, I'd love a website that can provide all the ebooks oreilly provides. But it needs to work on a tablet.
One thing I notice is that it simply does not render many code snippets well, especially when using the "page" (vs "continuous" scrolling). I don't get the impression they are doing QA on rendering quality. Not only external publishers, but O'Reilly books themselves! I also had a lot of problems reading Manning books in their app.
Rendering e-books properly is a pretty big table-stake thing.
"Influenza vaccination is associated with significantly lower odds of myocardial infarction (MI), according to a large meta-analysis published late last week in BMC Public Health."
https://www.cidrap.umn.edu/influenza-vaccines/new-analysis-l...