I don't think so?
Yes. It's using a global variable to canonicalize instances so that reference equality is value equality. An LRU cache will evict things that are still in use, so that the canonicalization process returns a different instance for the same value. (If it doesn't evict anything still in use, it's strictly inferior to just tying to the garbage collector anyway.) This will break the assumption that reference equality is the same as value equality that the rest of the code depends on.
Cheating is a big draw to Windows for semi-pro gamers and mid streamers. What else is there to do except grind? Windows gives the illusion of "kernel level anti-cheat," which filters out the simplest ones, and fools most people some of the time.
For instance, a common cheat in Street Fighter 6 is to trigger a drive impact in response to the startup of a move that is unsafe to a drive impact. That is recognizing the opponent's animation and triggering an input. There's no part of that which cares where the game simulation is being done. In fact, this kind of cheating can only be detected statistically. And the cheats have tools to combat that by adding random triggering chances and delays. It's pretty easy to tune a cheat to be approximately as effective as a high-level player.
Kernel-level anticheat isn't a perfect solution, but there are people asking for it. It would make cheating a lot harder, at least.