As you mentioned, the big issues are around infections. It completely wipes out the immune system, including all vaccinations. Every vaccination needs to be taken again, once the body is recovered from the initial therapy.
My Mum recently contracted COVID and is in hospital being given Paxlovid. She had COVID a while ago and it was nothing compared to her current state. CAR-T made it significantly worse but will hopefully be worth it in the long term.
I'm saddened by your news but - given what I've experienced with my Mum during her cancer journey - can understand the difficult decision you've made.
Are there any SMEs that have worked with both OpenSearch (the fork) and ElasticSearch? Are there significant differences?
I know the AWS fork had the big difference back then of having RBAC built into their Kibana portion.
There are some Elasticsearch features that were part of X-Pack (their commercial offering) so aren't included in the OpenSearch fork. Some of those features are really nice to have and make life much easier; the enrich ingest processor is something I really miss in OpenSearch.
The biggest differences are in the tooling around Elasticsearch. All the observability stuff, the SIEM features, various integrations, and now the AI fluff. I've worked with clients in different sectors and - aside from the observability stuff (which is really nice) - none have had an appetite for any of that.
The OpenSearch team is doing some really cool stuff and the project has come a long way. I'm sure it'll continue to improve. It has a very loyal customer base and even has its own annual event; OpenSearchCon 2024 is next month!