Cool study. I really want to believe the results, but the effect on life extension is so large (see figure 2B) that I find it hard to. Maybe there was some uncontrolled confounding factor? It is noted in the 'Methods' section that 'Researchers were not blinded to group allocation [...]', which is unfortunate.
Readit Newsawanderingmind commented on The Collapse of the FDA nytimes.com/2025/07/08/ma... · Posted by u/littlexsparkee
i know this is a very political thing now but i've had friends (smart phd people who work industry) very annoyed at the fda for many years, and maybe this collapse is good!
the fda started with a noble mission but they've been getting heavy handed. or better cliched - slow handed with getting things certified.
you can solve this one or two ways: drop regulation or increase staffing.
so many institutions have unnecessary fluff, tremendous red tape (why do i need environmental review to stick a shed in my backyard??), our modern lives have too much regulation.
let's hope for the best.
the old system is holding back drugs.. there should have been more ozempics, more breakthroughs had the fda not been so slow. companies have a strong incentive not release bad drugs now.. lawyers are not cheap and law firms know money can be made.. it's not the 1930s anymore.. (okay it's still the 1930s in certain places of the world, that's a criticism)
typing this out hoping to convince any regulation reduction is good reduction, i thought of a third fda option: the fda let's everyone go hog wild initially but looks at the top consumed products and checks them for safety and efficacy each year.
This perspective is addressed in the article... TLDR; that doesn't seem to be where this is going.
This is a rare type of article - a concrete analysis of different approaches to programming (that are arguably themselves reflections of different cognitive styles), that outlines the shortcomings of one approach in a specific domain, without generalising too much.
awanderingmind commented on For algorithms, a little memory outweighs a lot of time quantamagazine.org/for-al... · Posted by u/makira
At the cost of sounding ridiculous: can there be a notion of "speed of light" in the theory of computation, determining the ultimate limit of memory (space) vs runtime?
You mean something like this https://en.wikipedia.org/wiki/Bremermann%27s_limit or this https://en.wikipedia.org/wiki/Quantum_speed_limit?
awanderingmind commented on What does the end of mathematics look like? awanderingmind.blog/posts... · Posted by u/awanderingmind
I think people like author are positive about us, humanity, being able to build AI or something being very close to that.
I am not.
From the energy efficiency perspective human brain is very, very effective computational machine. Computers are not. Thinking about scale of infrastructure of network of computers being able to achieve similar capabilities and its energy consumption... it would be enormous. With big infrastructure comes high need of maintenance. This is costly and requires a lot of people just to prevent it from breaking down. With a lot of people being in one place, there socioeconomical cost, production, transportation needs to be build around such center. If you have centralized system, you are prone to attack from adversaries. In short I do not think we even close to what author is afraid of. We just closer to beginning to understand what is the need to actually start to think about building AI - if ever possible at all.
I hope you are right - the point about energy efficiency is certainly spot on, and I do think it is possible that people are getting carried away by analogies when discussing the topic (I wrote something about that too, but will avoid linking to it here to avoid excessive self-promotion).
That said, the article doesn't assume such a thing will happen soon, just that it may happen at some time in the future. That could be centuries away - I would still argue the end result is something to be concerned about.
awanderingmind commented on What does the end of mathematics look like? awanderingmind.blog/posts... · Posted by u/awanderingmind
I would say that I am envy that someone can write like that. I can't write in such manner in my native language, let alone in the second one: English.
It is nice to read or hear someone speaking like that, considering we are surrounded by low quality, easy to consume content nowadays.
And I am envy of such skill because I like to think about myself as not entirely being stupid, still I would never be able to write/speak this way because I just do not have an aptitude towards that.
English is my second language too - ironically I am not so as proficient in my mother tongue, due to globalisation/imperialism. But it's ok, fortunately I love the language!
awanderingmind commented on What does the end of mathematics look like? awanderingmind.blog/posts... · Posted by u/awanderingmind
> The camera didn't kill painting
But it did. Painter used to be a trade where you could sell your painting skills as, well, a skill applicable for other than purely aesthetic reasons, simply because there were no other ways to document the world around you. It just isn't anymore because of cameras. Professional oil portrait painter isn't a career in 2025.
Well, it is still a career, but it's very niche, and more attuned to 'art' than 'documenting the world'.
awanderingmind commented on What does the end of mathematics look like? awanderingmind.blog/posts... · Posted by u/awanderingmind
I love the language of this article :-)... it may be florid, but that's quintessentially human.
About the substance, I agree that there are fair grounds for concern, and it's not just about mathematics.
The best case scenario is rejection and prohibition of uses of AI that fundamentally threaten human autonomy. It is theoretically possible to do so, but since capital and power are pro-AI[^1], getting there requires a social revolution that upends the current world order. Even if one were to happen, the results wouldn't last for too long. Unless said revolution were so utterly radical that would set us in a return trajectory to the middle ages (I have something of the sort published somewhere, check my profile!).
I'm an optimist when it comes to the enabling power of AI for a select few. But I'm a pessimist otherwise: if the richest nation on Earth can't educate its citizens, what hope is there that humans will be able to supervise and control AI for long? Given our current trajectory, if nothing changes, we are set for civilization catastrophe.
[^1]: Replacing expensive human labor is the most powerful modern economic incentive I know of. Money wants, money gets.
Thanks for the positive feedback on my writing style! Based on feedback in this thread it seems to be a divisive topic, haha.
According to the researchers, “the triggers are not contextual so humans ignore them when instructed to solve the problem”—but AIs do not.
Not all humans, unfortunately: https://en.wikipedia.org/wiki/Age_of_the_captain