Targets all deviding cells, with the faster-deviding cancer cells more affected.
right
Readit Newsatrexler commented on Periodic fasting starves cisplatin‐resistant cancers to death emboj.embopress.org/conte... · Posted by u/sjcsjc
atrexler commented on Periodic fasting starves cisplatin‐resistant cancers to death emboj.embopress.org/conte... · Posted by u/sjcsjc
Fast for how long ? Few days a week ?
I've no idea about the fasting stuff. Just thought its important to make clear this particular study is all about doing stuff to cells or lumps of cells in dishes (again sorry if I missed more involved model system in the paper). Whether thats a good model for cancer in people and how fasting interacts with that I honestly have no idea.
atrexler commented on Periodic fasting starves cisplatin‐resistant cancers to death emboj.embopress.org/conte... · Posted by u/sjcsjc
Rewritten for normal people:
Cancer sometimes becomes resistant to chemotherapy, but we did a study that shows a certain type of lung cancer is highly dependent on a certain amino acid and when you fast intermittently it deprives the cancer of that amino acid and causes the cancer cells to die.
Well, to be precise- this study shows no evidence of a fasting effect.
they show if you starve cells in a dish in a way that might mimic what happens when you fast, you can kill the cells. I didn't see any mention of even mouse studies in there, so I don't know what their in vivo model was but it mostly looks like cell culture to me (apologies if I've missed that). Extrapolating that to humans is extremely hard.
For sure a promising result but its pretty preliminary.
atrexler commented on Periodic fasting starves cisplatin‐resistant cancers to death emboj.embopress.org/conte... · Posted by u/sjcsjc
Not much of a suprise really. It fits the model that cancer cells are weaker, that any stress to the entire body might see them die off first. That is the basis of non-targeted chemo and radiation treatment. You apply the stress and hope it kills the cancer before the patient. So here we starve the patient and see the hungry cancer cells suffer the most. But just dont go so far that the immune system suffers too. That wont end well.
this isn't how chemotherapy works. traditional chemo targets rapidly dividing cells in the body: cancer, hair/skin, intestinal lining cells. That's why you get those side-effects.
atrexler commented on The rescue of the crew of the yacht Django (2016) boatingnz.co.nz/articles/... · Posted by u/curtis
atrexler commented on How to start a lab when funds are tight nature.com/articles/d4158... · Posted by u/okket
Actually I find the high tier journals such as Nature do add value through editorials, keeping tabs on industry trends, and various programs. It's the low impact factor journals that are glorified FTPs that have to go.
Yes but how much value really?
https://www.ascb.org/newsletter/novemberdecember-2016-newsle...
Overload your gels much bro?
JK- just looking for those impurities.
atrexler commented on For more and more people, work appears to serve no purpose newyorker.com/books/under... · Posted by u/wyclif
"Who's more foolish, the fool or the fool who follows him?"
atrexler commented on Sci Hub repository torrents of scientific papers gen.lib.rus.ec/scimag/rep... · Posted by u/jacquesm
https://www.ascb.org/newsletter/novemberdecember-2016-newsle...
"This money is effectively a surcharge, or tax, on scientific research imposed not by a government but by a for-profit industry. Imagine for a moment how much research could be carried out using these resources if they were channeled back into our academic enterprise."
atrexler commented on Study Shows a Productivity Boost of Working From Home inc.com/scott-mautz/a-2-y... · Posted by u/mpweiher
I wonder at how this would vary across industries and also company sizes. I'm surprised the study had positive results at a relatively large firm. I think its easy to imagine working-from-home gains in small firms and startups where typically there's a much stronger selection for highly motivated and enthusiastic people. It's not clear the same would result in a huge firm where you have less of that selection.
Also how does one measure productivity? (this is probably a naive question as a relative neophyte) An article I found on this says they were 13.5% "more efficient" but I'd love to get the details on what that means. Its a travel agency so are they just booking, scheduling, organizing, etc? Would love to see a similar study in a SW dev environment, alternately something less tech focused but collaborative...I dunno but something creative most likely.