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Tharkun commented on Microsoft Japan’s 4-day workweek experiment sees productivity jump 40%   cnbc.com/2019/11/04/micro... · Posted by u/known
cosmodisk · 6 years ago
Unless it's some sort of C level meeting with tje board on quarterly basis, I seen no reason why any internal meeting should be more than half an hour long.
Tharkun · 6 years ago
I agree. Sadly not every manager got that memo.

My brief time at $megacorp taught me to recognize when a meeting turns into unproductive bullshitting, at which point I just walk away and go back to work. YMMV.

Tharkun commented on Microsoft Japan’s 4-day workweek experiment sees productivity jump 40%   cnbc.com/2019/11/04/micro... · Posted by u/known
Tharkun · 6 years ago
Maybe the headline should reflect this gem:

> That boon was thanks in part, Microsoft said, to meetings capped at 30 minutes and an increase in remote conferences.

From my past experiences in megacorps, there are so many meetings it sometimes feels like that's all you're doing.

Tharkun commented on The Joys of Unix Keyboards   donatstudios.com/UNIX-Key... · Posted by u/ecliptik
mdszy · 6 years ago
Every keyboard I've ever used I've remapped the caps lock to control, whether in hardware (like on my pok3r) or in software (on my work computer). I have a hard time ever using a keyboard without this remapping done.
Tharkun · 6 years ago
I've gone down this route several times. I've moved Esc, Ctrl and Win (or whatever you call it, Meta?) to the CapsLock position. But for some reason my left pinky just doesn't like that spot. It's a slightly awkward angle, and I use Esc/Ctrl/Win so much that having any of them in that spot tires out my pinky.

One row up or down is fine. But home row far left is hell. Maybe it's simply because my hand grew into it over several decades. Instead, I use CapsLock to lock my screen.

Tharkun commented on Ask HN: Best solutions for keeping a personal log?    · Posted by u/bnj
Tharkun · 6 years ago
I use Zettlr + git to keep my personal log/lab notes/daily journal. It's just a fancy markdown editor, to it should be trivial to write some shell foo to pull in data from whatever source you like.
Tharkun commented on FDA approves new treatment for adults with migraine   fda.gov/news-events/press... · Posted by u/apsec112
ekianjo · 6 years ago
for 2), this is not news, back in October 2019 Lilly got their drug approved as well in this class: https://www.bloomberg.com/news/articles/2018-09-28/eli-lilly...
Tharkun · 6 years ago
The news here is that ubrogepant is a tablet taken as an abortive, while emgality etc are injections taken as a preventative.
Tharkun commented on FDA approves new treatment for adults with migraine   fda.gov/news-events/press... · Posted by u/apsec112
AmericanChopper · 6 years ago
Diclofenac works very well for me. Tablets work within an hour most of the time, and intramuscular shots work within about 20 minutes every time. But the long term potential side effects aren’t great, so new options would be fantastic.
Tharkun · 6 years ago
Diclofenac is an NSAID painkiller. It comes with all the usual risks and contraindications of any other NSAID.

Migraine abortives like triptans and migraine inhibitors like these CGRP antagonists (erenumab and now ubrogepant) are not painkillers. They attempt to stop the migraine, not just numb the pain. They're both in a league of their own.

Tharkun commented on OnlyKey: Open-Source Alternative to YubiKey   onlykey.io/... · Posted by u/mcone
samatman · 6 years ago
This would require new hardware.

If one is already going to be purchasing new hardware, one may as well get a QMK keyboard. This way you can program it with any keyboard layout you would like, and it will work on any computer without having to change the system defaults.

Clearly this doesn't help with built-in keyboards such as found on laptops; the clear workaround for this specific product is to allow it to import keyboard layouts in the various OS-specific forms they exist in.

Tharkun · 6 years ago
Sadly it doesn't seem to work that way. BE/AZERTY keyboards, for instance, have a physical key that US/QWERTY keyboards do not (<>\). The OS will ignore that key unless it's set up to use a layout that includes the key. There is no way to program a QMK keyboard to fix that (unless you change the OS to run the BE layout), because QMK does not map keypresses to characters. It maps keypresses to keycodes, which depend on OS keyboard layouts, specifically US/QWERTY and sometes DVORAK. At least that's how I see it.
Tharkun commented on OnlyKey: Open-Source Alternative to YubiKey   onlykey.io/... · Posted by u/mcone
young_blood · 6 years ago
There's currently an issue (and an open PR) in to add dvorak support, though, I'm not sure if/when it'll be merged.

https://github.com/trustcrypto/OnlyKey-Firmware/issues/85

Tharkun · 6 years ago
There are many, many keyboard layouts out there. Maybe it's time for an input standard that acknowledges this fact, instead of endlessly putting the onus on OS developers and users. Maybe keyboards should output UTF8 instead of messy keycodes.
Tharkun commented on Hepatitis C kills more Americans than all other infectious diseases combined   scopeblog.stanford.edu/20... · Posted by u/vo2maxer
idclip · 6 years ago
Jesus how much did these drugs cost to develop? Are these numbers justified?
Tharkun · 6 years ago
Drug development is incredibly costly. It's also something of a long term gamble. It can take 10-20 years to develop a new drug. A lot of that time is spent testing safety and waiting for approval. As a drug company, you need to have several new drugs in your pipeline at any given point, or you'll be seriously fucked if one (or more) of your products don't pan out. It's basically a high-risk-high-reward type of gambling situation.

Imagine having thousands of people on payroll, some working on drug design, some designing experiments to test the drugs, some doing the legal paperwork to get drugs approved etc, and suddenly the patent for your best selling drug expires and your latest drug doesn't work. You're pretty much boned.

Tharkun commented on New laser ultrasound technique can remotely image the inside of a person   news.mit.edu/2019/first-l... · Posted by u/happy-go-lucky
tjohns · 6 years ago
This sounds a lot like optical coherence tomography (OCT), which is essentially laser-based “ultrasound” used to image the inside of retinal tissue. (It’s not actually ultrasound, it’s entirely optical but uses similar principles.)

https://en.m.wikipedia.org/wiki/Optical_coherence_tomography

It’s already a common diagnostic tool used for patients who are at risk for glaucoma. By creating a 3D cross section of the eye’s retinal structures, it lets physicians detect early damage from the disorder, hopefully before any vision loss.

Tharkun · 6 years ago
Thanks for linking to that. I had this done a while back but didn't know what it was called or how it worked. If only all imaging techniques were as fast and pleasant this one. It was over in seconds. Although I suppose the small size of retinas likely play a part in that as well.

u/Tharkun

KarmaCake day3342February 11, 2011
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