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yadaeno commented on Evidence for hepatitis C virus involvement in bipolar disorder and schizophrenia   nature.com/articles/s4139... · Posted by u/PaulHoule
hungmung · a month ago
Interestingly, the new drug used to cure hep c can throw you into a manic episode. It's something that's still being looked into because they aren't sure if the medicine can cause it directly, or if it's just the sudden life change, or if it's a response to your body suddenly not having to fight a chronic infection so you have more energy that you aren't used to handling.
yadaeno · a month ago
Hep C is already curable with antivirals, wouldn’t we notice this with existing treatments if this theory was correct?
yadaeno commented on Tao on “blue team” vs. “red team” LLMs   mathstodon.xyz/@tao/11491... · Posted by u/qsort
__s · a month ago
Defense in depth is a security best practice because adding shit to a mess is more feasible than maintaining a simple stack. "There are always systems you don't know about" reflects an environment where one person doesn't maintain everything
yadaeno · a month ago
I think you are confusing “security through obscurity” and “defense in depth”.

You can add layers of high quality simple systems to increase your overall security exponentially, think using a VPN behind TOR etc.

yadaeno commented on Scientists may have found a way to eliminate chromosome linked to Down syndrome   academic.oup.com/pnasnexu... · Posted by u/MattSayar
Henchman21 · a month ago
And frequently we decide they’re damaged. Seems like its really the rest of us who are damaged.
yadaeno · a month ago
There’s another side to this. They place a large burden on the people taking care of them. Many parents also report that they regret conceiving children with Down syndrome.
yadaeno commented on CBA hiring Indian ICT workers after firing Australians   ia.acs.org.au/article/202... · Posted by u/theteapot
kannanvijayan · a month ago
When I was a fresh immigrant child comments like these used to make me feel more uncomfortable than they do now. How I perceive these comments has changed over time.

What I want to address about this comment is the implicit identity associations involved. It's clear that you're drawing an identity distinction between "Canadian" and "Indian".

One of the things I've noticed about my own personal associations is that my own identity as an "Indian" kind of dissolved over the course of a decade or so after I immigrated as a child.

And when it evolved it didn't evolve in the direction of "Canadianness", for some generic definition thereof. My cultural identity broadened along horizons that had nothing to do with nationality.

When I think of "my tribe" now, it's on a values and interest basis. "My people" aren't Canadians or Indians, they're programmers and engineers and scientists and mathemeticians. Where I draw identity lines, it's no longer along national lines. My tribe's Gods are Turing and Church. Our saints are Torvalds and Carmack and Stroustrup and Van Rossum and Wall. We are friendly with the neighboring tribes that follow Euler and Goedel, as well as the yonder followers of Einstein and Newton and Feynman.

And I think that perspective dichotomy is reflective of an underlying deep shift in how people form identities, one that's being driven by the rise of instant, rich global communications through the internet.

So when I read comments like yours these days, I see yet another sign of the tension between that old structure and the new.

To bring this back to a Canadian context, Stephen Harper (former conservative PM) actually called this out very astutely a long time ago when talking about the Somewheres vs the Anywheres:

https://macleans.ca/politics/ottawa/stephen-harper-has-some-...

> Harper argues that today’s conservative populism deserves a respectful hearing because it harnesses the legitimate anxieties of the Somewheres, who haven’t been doing all that well in the globalized economy. As for the Anywheres, they don’t get it.

I'd only disagree about that last statement. I get it :) It's just that having been born in a very Somewhere place and having become an Anywhere, I really can't explain the depth of freedom you feel when you escape those identity bounds.

It's not that I don't understand the cultural perspective of the Somewheres. It's just that I see it as a prison.

yadaeno · a month ago
Your system of drawing lines and forming “tribes” within social classes reminds me of the caste system.

Deleted Comment

yadaeno commented on What I learned gathering nootropic ratings (2022)   troof.blog/posts/nootropi... · Posted by u/julianh65
Analemma_ · 2 months ago
The tl;dr is:

1. Apart from ADHD medications, which are very powerful, most drugs and weird obscure supplements have little effect (there are some intriguing but noisy results about peptides).

2. Exercise— especially weightlifting and HIIT— is also very powerful. There's evidence of a dose-response curve where light exercise is good but intense is better.

Arguably this is pretty unsurprising, from an evolutionary perspective. It would be strange if our brains had "one weird trick" to perform a lot better with no downsides, since if it existed evolution should've found it. But being in good shape confers large benefits.

yadaeno · 2 months ago
> It would be strange if our brains had "one weird trick" to perform a lot better with no downsides, since if it existed evolution should've found it

It would not be strange at all. We are constantly evolving and so is our environment. This argument is very similar to the "efficient market fallacy", if the market was perfectly efficient there would be no opportunity to create value, but in reality it is highly imperfect.

yadaeno commented on U.S. bombs Iranian nuclear sites   bbc.co.uk/news/live/ckg3r... · Posted by u/mattcollins
yadaeno · 2 months ago
Iran is the aggressor here. Iran has been funding and arming multiple proxies to fire missles into Israel for the past 50 years
yadaeno commented on TI to invest $60B to manufacture foundational semiconductors in the U.S.   ti.com/about-ti/newsroom/... · Posted by u/TMWNN
LPisGood · 2 months ago
I think drawing a parallel between those situations is odd.

One is a war of aggression, one is of defense. One where American military action is being considered, one is not.

yadaeno · 2 months ago
Iran has been attacking Israel for 50 years through proxies. I don’t think it’s a clear “attack vs defense”. Also now is the time to deal with Iran and restore a sane government before they have a chance to add nukes to the equation.
yadaeno commented on Airlines are charging solo passengers higher fares than groups   thriftytraveler.com/news/... · Posted by u/_tqr3
ncruces · 3 months ago
I didn't.

If you wanna save money, you figure it out. If you don't wanna figure it out, you leave money on the table.

They're selling (negative) convenience, but that's pretty much by design.

yadaeno · 3 months ago
Selling negative convenience very succinctly describes the issue.

You already have to spend time researching airlines, buying tickets in advance, etc. but now in addition to that there is a completely contrived layer of bullshit I need to know about.

You can extend this concept even further and imagine literal series of hoops that you must jump through to earn “cash back” on your ticket at the end of the flight.

yadaeno commented on Airlines are charging solo passengers higher fares than groups   thriftytraveler.com/news/... · Posted by u/_tqr3
stmw · 3 months ago
Here is why I think these kinds of dynamic pricing practices are bad: it may be perfectly fair and legal, but it forces a non-negligible number of humanity to waste time and/or energy to figure out if it's happening, how to work around it if it is, and just generally waste human potential on something that should be a simple commodity.
yadaeno · 3 months ago
Same with points systems. Why am I forced to understand your made up currency and status system to get the full value of my money.

There might be some benefits to price discrimination (which is in effect what a point systems achieves) but the collective time wasted dicking around with points isn’t worth it. Make all point systems illegal.

u/yadaeno

KarmaCake day829August 9, 2017View Original