As much as I love not having to see Trump on Twitter now.. the future of social media is going to be fully decentralized and distributed (whether we like it or not). The Free World will need a much better immune response to this kind of radicalization than deplatforming people.
Readit Newsstephenhess commented on Permanent suspension of @realDonaldTrump blog.twitter.com/en_us/to... · Posted by u/minimaxir
stephenhess commented on Startup mistakes: Lessons from failed startups failory.com/blog/startup-... · Posted by u/mitchbob
Where should the primary responsibility for product market fit lie within a startup? E.g. product owner, CTO, CEO, .. ?
CEO is the primary but everyone in a startup needs to take responsibility for this. The core goal of a startup is to discover a "scalable and repeatable" business model.
https://steveblank.com/2010/01/25/whats-a-startup-first-prin...
stephenhess commented on San Francisco proposes “IPO tax” on eve of Uber offering axios.com/san-francisco-p... · Posted by u/kimsk112
San Francisco is one of the most mismanaged major cities in the world and it's on such a negative trajectory. It's blessed with an incredibly successful homegrown tech industry, but there's only so much that can do to hide the underlying disfunction and the cracks are starting to show.
As a VC in San Francisco, I've recently given up my residence here, and am increasingly looking outward for tech and culture. I see many of my peers doing the same, moving east, south, or out of the country entirely.
It's bittersweet. I used to love San Francisco, but have recently entirely lost faith in it ever getting better. I've given up. And honestly, I feel a weight lifted from not having to care and constantly deal with the frustration anymore. There's so much tech & entrepreneurship worth promoting outside of SF, and it's so often overlooked.
Bye!
stephenhess commented on A Design Lab Is Making Rituals for Secular People theatlantic.com/technolog... · Posted by u/raleighm
Love this. I'm as harsh of a critic of organized religion as you'll find but I think secular culture has a lot to learn in terms of how religious rituals and habits can foster human excellence, joy. And finding a way of reformulating these to be consistent with scientific thinking (i.e. throw out the mythology)
Specifically, I've been really curious to understand the relationship between faith and anxiety/depression. You see a surge of mindfulness and meditative practices in the Bay Area that appear like secular replacements for how "faith" in the Judeo-Christian tradition helps people face the unknown and the fundamental uncertainty of the universe.
stephenhess commented on Type 2 diabetes can be reversed with a low-calorie diet discover.dc.nihr.ac.uk/po... · Posted by u/DanBC
...or you could not starve yourself on <900 calories a day and instead be a sane person and just eat low carb:
https://link.springer.com/article/10.1007%2Fs13300-018-0373-..."Insulin therapy was reduced or eliminated in 94% of users; sulfonylureas were entirely eliminated in the CCI. No adverse events were attributed to the CCI."
Wow, that's pretty extraordinary, isn't it? Every single person in the non-control group eliminated the need for sulfonylureatic compounds and a massive 94% reduced their insulin level or completely got off insulin altogether. All with no adverse affects being recorded.
You don't need to starve yourself or go on some ridiculous diet. You just need to eat low carb and eat clean (a.k.a. "real" food) and your body will begin to heal in nearly every case. I suspect the few test cases that didn't improve were so far gone they were too metabolically impaired to achieve any positive results. The damage was likely too extensive and age possibly played a factor. For everyone else, it appears they can get rid of diabetes...if they actually care enough to do so.
With you until that last part.. older populations that go through diabetes prevention / weight loss programs actually do better than younger folks. Also, "if they actually care enough to do so" is a tricky statement. Many folks that are overweight have tried losing weight numerous times only to gain it back and have leaned on confusing (and often incorrect) advice about diet, exercise and its relationship to weight loss (e.g. the food pyramid). They go through waves of motivation like anyone else. There's a good opportunity for the healthcare industry to engage with people at that level, in the way mental health professionals support people battling anxiety and depression. Would love to see more research targeted at that motivation point because I agree with you that the physiological mechanisms are pretty well understood at this point (at least in comparison).
stephenhess commented on Type 2 diabetes can be reversed with a low-calorie diet discover.dc.nihr.ac.uk/po... · Posted by u/DanBC
The subjects were under medical supervision ...
Also, non-insulin dependent which lowers the risk considerably
stephenhess commented on Type 2 diabetes can be reversed with a low-calorie diet discover.dc.nihr.ac.uk/po... · Posted by u/DanBC
We've known that low-calorie dieting has this effect for some time; unless I'm missing something, this looks like solid confirmation of this point but isn't adding much knew to our understanding of diabetes prevention. The big challenges in this space are adherence, scaling access to treatment and creating long-term lifestyle change that will help the patient maintain the weight that is lost.
There's good evidence that ketogenic diets have an additive metabolic effect beyond pure calorie restriction which is exciting. Virta Health is doing some interesting work here and just published some results that speak to this: https://link.springer.com/article/10.1007%2Fs13300-018-0373-...
| 5. Spend less than they make
Had they done that, they could survived long enough to find their niche. But throwing out multiples of your revenue out of your own pocket means you're on borrowed time.