Sort of.

For things that run on Linux and other Unices yes.

For macOS UI programs and those that need specific permissions and for commercial programs stick with Homebrew but you can define what you want in homebrew in nix.

Pulumi is really a royal piece of shit. Why the f*ck am I writing code to do "deployment". In C# --> new Dictionary<string, object> when dealing with a values.yaml for instance. The whole need to figure out when and when not to use Apply.

Give me Terraform (as much as I hate it) any day.