Somewhat amusingly, the library is a subordinate of the county. If the library is in fact poorly managed, the poor management is the fault of the board of supervisors.
Somewhat amusingly, the library is a subordinate of the county. If the library is in fact poorly managed, the poor management is the fault of the board of supervisors.
If you’re working on an architecture where a single multiplication and a bit shift is cheaper than N xor’s, and where xor, add, and sub are all the same cost, then you can get a performance win by computing the sum as N(N+1)/2; and you don’t need a blog post to understand why it works.
I probably would have written it with a single loop, using the `enumerate` iterator adapter. But in Python, two loops is almost certainly more efficient.
Title should have a (2014) in it: Introduction to the A* Algorithm (2014).
1 points, 8 months ago, 1 comments: Introduction to the a* Algorithm (https://news.ycombinator.com/item?id=41897736)
202 points, 3 years ago, 30 comments: Introduction to the A* Algorithm (2014) (https://news.ycombinator.com/item?id=30287733)
4 points, 5 years ago, 1 comments: Introduction to the a* Algorithm (https://news.ycombinator.com/item?id=24146045)
201 points, 7 years ago, 14 comments: Introduction to A* (2014) (https://news.ycombinator.com/item?id=18642462)
5 points, 7 years ago, 0 comments: Introduction to A* (https://news.ycombinator.com/item?id=16190604)
It’s even more marvelous if it helps you recognize that the difference between BFS and DFS is how you pick the next node to explore out of your bag of unexplored nodes. That symmetry is easily lost if DFS is only taught as a recursive algorithm.
Let it keep coming up every couple years to marvel a new generation of programmers.
The electrical engineer suggests it's not measurable unless you apply current and also asks "when" after the current is applied referring to the distributed inductive and capacitive element and the speed of field propagation. The mathematician goes to a bar and has a stiff drink after hearing that.
One is where the components on the schematic represent physical things, where the resistors have some inductance and some non-linearity, and some capacitance to the ground plane and so on. This is what we mean by schematics when we’re using OrCad or whatever.
There is another interpretation where resistors are ideal ohms law devices, the traces have no inductance or propagation delay or resistance. Where connecting a trace between both ends of a voltage source is akin to division by zero.
Sometimes you translate from the first interpretation to the second, adding explicit resistors and inductors and so on to model the real world behavior of traces etc. if you don’t, then maybe SPICE does for you.
Infinite resistor lattices exist only in the second interpretation.
Viruses often use immune or other surface proteins as receptors presumably because they are important (can't be down-regulated too much).
For the pigs, it looks like they deleted just the SRCR5 domain of the CD163 protein. CD163 is used by macrophages to scavenge the hemoglobin-haptoglobin complex.
A 2017 article (of 6 pigs?) suggests that the engineered pigs are resistant to the virus "while maintaining biological function" although I don't see any experiments comparing hemoglobin-haptoglobin scavenging ability of engineered vs unedited pigs. https://pmc.ncbi.nlm.nih.gov/articles/PMC5322883
This 2024 study (of 40 pigs) found 'no significant difference' in a panel of health measures and meat quality, except that the engineered pigs had statistically significantly more greater backfat depth than the edited animals. https://www.frontiersin.org/journals/genome-editing/articles...
Interestingly, the mean weight of live pigs is slightly higher for edited pigs but lower for dead pigs. Total fat slightly higher for the edited pigs. These numbers are not statistically significant (but only a small number of pigs were tested).
The pigs were assessed at approximately 205 days in age. Pigs can live up to 20 years. Would be good to test the long term effects and the effects over multiple generations.
This paragraph is striking:
> Under the conditions of these studies, neither homozygous nor heterozygous or null pigs inoculated with PRRSV showed the acute clinical signs typically observed in commercial pigs and had overall low depression and respiratory scores (1). This may be explained by the fact that these pigs were sourced from a high-health farm and managed with minimal stress, which differs from disease expression under commercial conditions.
Sounds like the genetic editing is not necessary as long as the farm conditions are good..
It would be good to test for those things if the concern was for the long-term health of the pigs. The concern is whether or not they produce safe meat. Somewhere between most and all of the pork I've eaten in my life came from pigs less than a year old.
As near to 100% as makes no difference every single house is already wired for 240v. In fact wired for it and using it: electric ranges, stoves, dryers, etc are all 240v.
NEMA even defines 240v receptacles/plugs for normal amperage: NEMA 6-15 (two horizontal blades: meh face) and 6-20 (one vertical, one horizontal: wink with other eye closed). Unlike the common 240v dryer/large appliance cords that are huge and bulky 6-15 and 6-20 are about the same size as our current 120v plugs. They have the same compatibility as 5-15/5-20: The 15 amp version fits in the 20 amp receptacle but the 20 amp only fits 20 amp. And it is impossible to plug 120 into 240 or vice-versa. Everything made for 120v (to a rough approximation) is also rated for 240v.
Unfortunately no one bothers to install the 6-15/6-20 plugs. There is nothing stopping any builder from doing it standard, especially in the kitchen. There is nothing stopping a homeowner/buyer from asking for it either. But no one does. Therefore there is no market for appliances that use these plugs. And thus no demand to wire for them.
It would likely take a push from government, manufacturers, the NEC, etc to push for supporting 240v for common appliances. Start installing them in new homes. Offering the 240v version of electric kettles and such.
Note: some European appliances can be wired up this way and will run fine because they tolerate 60Hz but not all of them.
Almost no one, but I had a 6-15R put in my kitchen. Then I imported a 3kW tea kettle from the UK, lopped off the plug, and put on a 6-15P. And now my wife doesn’t have to wait very long for her hot water.
https://web.archive.org/web/20110409171021/http://www-03.ibm...
It has both the original typewritten scan and a searchable-text version right underneath.
Does anybody have any other insights?
I work on a product whose user interface in one place says something like “Copyright 2004-2025”. The second year there is generated from __DATE__, that way nobody has to do anything to keep it up to date.
Thank god we still teach quadratic equations, complex numbers, hyperbolic trig functions, and geometric constructions though. I don't know what would become of the world if most people didn't understand those things when we set them loose in the world.