Last year she started Zepbound (tirzepatide) and the inflammation went away, we went to Disney World again and she walked happily all day. Absolutely life changing. She didn’t even lose much weight and this was at the lowest dose.
A drug that influences a hormone causing effects on everything that hormone is involved in shouldn't be considered a wonder drug, it should be expected functionality.
It's only a wonder drug that does all these miraculous things if you think GLP-1 is only a weight management hormone. It's not, and you should expect effects anywhere it is involved in. A short list of tissues we know GLP-1 is involved in processes is:
- heart - tongue - adipose tissue - muscles - bones - kidneys - liver - lungs
Effects on these aren't miracles, they should be expected.
I am happy to hear you saw so many improvements, but it's because you had an issue with a hormone that is involved in a lot of things in the body. So it was going to express a lot of problems. It's not surprising that you see a lot of improvements when you begin to manage the underlying cause.
It's clear you have no idea what you're talking about. Every single case I'm talking about outside weight loss has nothing to do with having a deficiency of that hormone, rather it's fixed by the hormone raising. And given it was impossible to do otherwise, it's a wonder drug, of course. You don't really define wonder by how simple it is, but by the effects, which are tremendously beneficial to many.
Further, I stand by my prediction that in the long run the vast majority of why this drug will be considered an once-a-generation discovery, is not due to weight loss or appetite control, but in fact it's seeming broad spectrum benefits across many systems. And actually your list of effects it has are interesting, because if you investigate deeply the studies published, you'll find that the results are overwhelmingly positive - brain, heart, many organs.
Not really, it's that hormones don't do just one thing in the body. GLP-1 isn't just some weight management hormone.
> The one that stuck with me from a few weeks ago went like 'I puked up my own poop.'
That happens if you let constipation go on far too long, and is not something unique to GLP-1 meds.
This made me actually laugh. A drug that cures obesity and addiction alone would be a wonder drug.
This one also improves about a hundred odd immune disorders, including being a better general allergy drug than just about anything. My own extremely rare and terribly painful immune disorder is basically entirely cured by it - it completely changed my life, making even sleeping far better. But not just me, I have friends who have lifelong terrible allergies gone, lifelong pack-a-day smoking addictions completely gone, and so on...
"Not really" is truly either the most pessimistic take I've ever heard, or hopefully just completely misinformed.
It'll come to be known that these drugs are far better for people in a broad way than even thought today. They seem to have at least 4 effects that individually should be considered a "miracle."
Everything in plan mode first + AskUserQuestionTool, review all plans, get it to write its own CLAUDE.md for coding standards and edit where necessary and away you go.
Seems noticeably better than 4.5 at keeping the codebase slim. Obviously it still needs to be kept an eye on, but it's a step up from 4.5.
My only complaint is that there's an over-eager PID loop with lane keeping. If I want to pass a transport truck and want to kind of edge to the left of my lane when doing so, it will keep trying to compensate, which I can feel in the wheel, so I compensate for as well. And if I let go of the wheel and let it win, it suddenly flings me towards the right side of the lane.
I suspect this is because it isn't programmed to think that I'm making adjustments, it probably just thinks there's some weirdness in the vehicle dynamics/road characteristics that requires extra compensation.
But there was one thing that was quite bad, similar to yours. While passing a semi I pulled it to the left side and it actually yanked us right so hard and then over-corrected once again. Super scary moment, the only issue of the whole trip, but basically never passed with it on again.