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nums commented on Could long Covid be linked to herpes viruses? Early data offer a hint   nature.com/articles/d4158... · Posted by u/nope96
FollowingTheDao · 3 years ago
Any infection you have will deplete one nutrient or another, and if you have a genetic susceptibility, this depletion might be much greater than someone else. To correct these nutrition depletion to keep these viruses in check, you will need to take mega doses of the supplement for a short period.

If you are still one of these people that think zinc does not play a role in COVID outcomes I have nothing left to say but: By destroying the ACE2 receptor, SARS2 causes a depletion of zinc since zinc makes up the structure of ACE2 and prevents the recycling of zinc in the cell.

https://www.sciencedirect.com/science/article/pii/S120197122...

https://www.nature.com/articles/s41467-020-18880-0

And hey and guess what. They find that people with zinc deficiency have more herpes out breaks!

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283972/

Why? Because the same thing happens with herpes but with NECTIN1 receptor and ADAM10. Low zinc means less ADAM10 activity and more NECTIN1 on the cell and therefor more herepes virus replication.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906284/

So what might be happening with the low cortisol they speak of in the study?

ACE2 is all over the adrenal gland, and when ACE2 is destroyed the adrenal gland shuts down and cannot release as much cortisol.

https://www.frontiersin.org/articles/10.3389/fendo.2020.5931...

Now, many of you will come back as show me all the studies that reveal that zinc actually reduces cortisol. And I agree, but do you know why? When someone is not zinc deficiency, adding more zinc will trigger ADAM17 to cleave ACE2 off the cell and create Soluble ACE2. Zinc the ACE2 is not on the adrenal gland anymore cortisol will not be released.

https://www.mdpi.com/viruses/viruses-12-00491/article_deploy...

But in a zinc deficient state there is not enough ACE2 to start with and ADAM17 activity is also low. By taking zinc and correcting the deficiency you will increase activity for both ACE2 and ADAM17.

If you know someone or if you have long covid, I highly suggest that you at least get your serum zinc levels tested.

nums · 3 years ago
Great comment.

From prior research, the hormonal interactions around the thyroid and immune system are complex. You've boiled it down fairly well here as related to zinc.

Wasn't there some discussion about hydroxychloroquine being effectively only in conjunction with zinc as the hydroxychloroquine encourages cellular uptake of zinc. Ergo, zinc is the key ingredient.

Further, I seem to recall the book "The end of alzheimer's" (high recommend) talked alot about zinc wrt neurological health.

nums commented on Google Maps now requires WiFi scanning to use navigation    · Posted by u/b112
nums · 4 years ago
What is the best alternative to google maps on my iphone that doesn't sell/store my location data?
nums commented on Joe “just conversations” Rogan defends misinformation like a classic grifter   arstechnica.com/science/2... · Posted by u/feross
nums · 4 years ago
I enjoy listening to some of Rogan's podcasts. I don't agree with all of his opinions (or his guests). Also, I'm not into all of his topics (e.g., MMA).

That said, I'm interested in the criticism of him and this "misinformation" that keeps cropping up. So, I read the articles and, importantly, the comments. Rarely do I see criticism beyond simple ad hominem attacks.

Asking this community as it seems reasonable, am I missing something here? What's wrong with debating ideas with a 50/50 weighting of left/right topics for discussion (i.e., old "equal time" rules)?

nums commented on Abuse and the developing human brain (2000)   dana.org/article/wounds-t... · Posted by u/softwaredoug
bubblecheck · 4 years ago
Throughout childhood, I was subjected to serious physical abuse by my peers, as well as serious verbal bullying/psychological abuse.

I stood up to a long term bully with a below-the-belt comment, which led to extremely violent abuse from peers. One of the last incidents was on the property of a town police officer, before high school started (around 12 yrs old). The police officer stood by while I was horribly beat up (punched full blast to my balls) by a scumbag with a group of people behind him.

The physical abuse included acute trauma from repeated impacts via punches and full strength kicks to my head. Saw stars every time I was hit, like those old Batman comics.

I entered high school as a broken child with cemented learned helplessness. Never the same.

Now homeless and destitute. I became permanently suicidal after grade school, totally afraid of death. Trapped in an unwanted life. Just went homeless yet again last night suddenly. The one shelter here seems like a psyop of sorts: in view of wealthy people, under blinding bright lights. Fodder for the wealthy, like a dystopian plot in popular Netflix shows.

I now suffer from tinnitus and hyperacusis picked up from overexposure. I am a destitute middle aged white male college dropout. Suicidal all of the time. This time going homeless I have no vehicle to sleep in. It's warm here but I am unsheltered. Demoralized, defeated, and hoping to die.

I beg of God to forgive me and grant me peace in the afterlife, whether I am able to complete suicide now or later.

nums · 4 years ago
Hoffman Process is life changing

Deleted Comment

nums commented on The Revenge of the Hot Water Bottle   lowtechmagazine.com/2022/... · Posted by u/Glench
bryanlarsen · 4 years ago
15A outlets are only rated that for instantaneous current. For continuous current, appliances are only allowed to pull 80%. So kettles in the US are 1400W, half that of British kettles.

Like many modern kitchens, I have 20A outlets. Current code says that you either have to have 20A circuits in the kitchen or split 15A circuits. What the electrician chooses to install depends on whether 14/3 or 12/2 wire is cheaper that day.

One of my pet peeves is that I can't buy a 20A 1900W kettle. There has to be enough market demand for one? Put a big picture of a NEMA 5-20 outlet on the front so that fewer people get confused.

nums · 4 years ago
14/2 or 12/2 :-)
nums commented on The Gold Standard and the Great Depression (1997)   nber.org/papers/w6060... · Posted by u/VHRanger
jihadjihad · 4 years ago
Ben Bernanke has studied and written [0] extensively about this topic; a copy of a speech he delivered at Washington and Lee University in 2004 can be found at [1] for those interested.

0: https://www.nber.org/system/files/chapters/c11482/c11482.pdf

1: https://www.bis.org/review/r040305e.pdf

nums · 4 years ago
"Helicopter" Ben famously said that the Great Depression could have been averted by throwing $100 bills from helicopters to pump liquidity into the economy.

I believe the implementation of this concept via the Fed (bank of banks) is the real issue. Basically, liquidity goes to the banks. Anyone having a relationship with banks gets access to this liquidity and benefits. Of course, we plow these "gains" back into assets (hard or stock market), this drives up prices, and we get asset inflation. For the person renting an apartment, leasing a car, and with credit card debt ... well, they lose. The trickle down doesn't work. You can interpolate and extrapolate from this brief comment, and I believe that this is the fundamental source of the expanding rich/poor divide.

nums commented on Hospitals lift curtain on prices, revealing giant swings in pricing by procedure   healthcaredive.com/news/h... · Posted by u/paulpauper
flowerlad · 4 years ago
The solution is to make the consumer participate in driving costs down. One employer I know of has an excellent solution to the problem: Make employees pay 100% of the bill up to a certain amount, such as $6000. That's a large amount, but the employer then contributes a large amount to your Health Savings Account (HSA), such as $4000. This amount is for you to keep regardless of whether you have any health bills or not. (This money can be used for medical expenses only, but can be used any time, including after retirement). So the maximum you will spend out of pocket per year is $2000. How does this encourage the consumer to scrutinize and control medical expenditure? Because the first $6000 of medical spending in a year is "your money". This is money you'd be able to keep in your HSA if you didn't have any medical expenses. This gives the consumer a strong incentive to reduce costs, question charges, avoid unnecessary services, and so on.
nums · 4 years ago
100% agree. It's a good start.

Also, I think emergency healthcare should be contemplated differently than ... I'll call it "premeditated healthcare". In one instance, the individual can make a deliberate shopping decision and weigh cost/benefit. That's fundamentally different than an ambulance taking you to the ER when you're bleeding out ... no price shopping then.

nums commented on Hospitals lift curtain on prices, revealing giant swings in pricing by procedure   healthcaredive.com/news/h... · Posted by u/paulpauper
nums · 4 years ago
I studied this years ago for years. My summary:

- a mandated MLR of 85% means the insurance companies have zero incentive to reduce the cost of items. In fact, their toplines and real (non%) profits increase as healthcare gets more expensive.

- industry profitability for insurance companies is around 3%. So, their overhead is around 15%-3% = 12%. They have an incentive to do their job cheaper. This pales in comparison to the 85% cogs.

- the small company cfo (me) has negative incentive to get involved in my employees' healthcare decisions. In fact, even being aware of cancer, pregnancy, etc. can be used against management in an employee lawsuit. No thanks. We just accept the situation and pay the bill.

- huge companies that can afford to self-insure can do it as they can firewall healthcare information from employment decision makers.

So, who in this system is going for cheaper healthcare:

- employees ... no

- insurance companies .. no

- healthcare providers ... no

- business paying the bills ... no

This bullshit billing structure is the tip of the iceberg. We have no freemarket incentives to keep down the cost of healthcare (i.e., carveout for high deductible insurance plans). Why would we expect otherwise?

nums commented on Tim Cook: You Deserve Privacy Online. Here's How You Could Actually Get It   time.com/collection/davos... · Posted by u/ArmandGrillet
nums · 7 years ago
Is this really about privacy? I'm skeptical that Apple doesn't track the hell out of me; I think they just want to sell more phones and don't want others to track us.

Instead, I think this is about asymmetric, non-negotiable contracts. Think about it.

Sure, I "consented" to the Apple EULA just like I "consented" to be tracked by all these websites. This brings up 2 points:

Fairness - Can this really be a fair contract if there is a vast power difference between the parties and a lack of alternatives?

Transparency - details hidden in the fineprint (50 page EULA or on a cookie consent form only available a click away)

I'm not usually one for govt regulation, but that seems the only solution here.

u/nums

KarmaCake day8October 25, 2018View Original