Overall populations don't have flawed genes... Before jumping on statins and such it's important fixing underlying cause and even then try to get actual data my having imagine to get soft plaque.. not cacb score which is only relevant in later stages

High cholesterol could be from high glucose/insulin damaging arteries

Or could also be from weight loss

Simplest fixes are

- eat low carb

- don't eat all day intermittent fasting

- walk after eating to lower spike

- eat olives which protects lining of veins and arteries

- avoid seed oils

- pick antiinflammatory foods and supplements

- take l-arginine and similar supplements, sunlight, green veggies, no mouth wash, exercise to increase nitrogen oxide production... Breath through nose as well

- exercise to increase good cholesterol

- sleep well and keep cortisol low (stress)

Cholesterol is needed for hormones, brain, everything... I believe statin are linked to Alzheimer