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kla-s commented on We’re secretly winning the war on cancer   vox.com/health/415812/can... · Posted by u/lr0
girvo · 2 months ago
What in the world is the putative mechanism behind that? That's fascinating.
kla-s · 2 months ago
I guess bioelectricity. Michael Levin is the guy to look at afaik.

Thanks @missedthecue, i wasn't aware this was productized and tested (though hoped it was)

kla-s commented on We’re secretly winning the war on cancer   vox.com/health/415812/can... · Posted by u/lr0
kla-s · 2 months ago
Any serious ideas for a recently removed glioblastom?
kla-s commented on Tell HN: Help restore the tax deduction for software dev in the US (Section 174)    · Posted by u/dang
jandrewrogers · 3 months ago
People greatly overestimate the amount of material cheating that happens, especially among large companies and the wealthy. I used to work for a Federal audit organization and almost all of the recoveries had a root cause in sloppy compliance and record-keeping practices rather than intentional malfeasance. It is broadly recognized as optimal that the recovered money should be several-fold the direct costs spent to recover it because this activity incurs a lot of non-obvious indirect costs. It is a variation on the principle that the optimum amount of fraud is non-zero.

Most of the blatant tax fraud is much lower down the economic ladder because below a certain threshold recovery doesn’t justify the cost and people know this. The amount you can get away with is far below the threshold where it would be worth the risk for wealthy parties. The best ROI for auditors in many of these cases is to make regular object lessons at random to discourage it rather than systematically prosecute it.

AFAIK, the increased spending at the IRS did not lead to concomitant offsetting recoveries. This is a predictable outcome, the amount of enforcement activity has been pretty finely tuned for decades to optimize ROI. Most of the recoveries come from changing focuses on compliance to areas that haven’t seen much enforcement activity in many years. Fighting entropy basically.

If you assume that most large recoveries are from sloppiness rather than systematic tax fraud, it changes what is going to be an effective strategy.

kla-s · 3 months ago
Whats your view on Cum-Ex?

And maybe as a Bonus what do you make of the smaller (relative) taxrate the bigger fish (companies/wealthier individuals) pay?

kla-s commented on Ask HN: Who wants to be hired? (May 2025)    · Posted by u/whoishiring
kla-s · 4 months ago
Location: Munich, Germany

Remote: Yes

Willing to relocate: Yes

Technologies: Python (PyTorch, TensorFlow), Reinforcement Learning, Medical Imaging, Machine Unlearning, Physics-informed ML, Quantum Computing, Protein Structure Prediction, NLP, Java, SQL

Résumé/CV: https://drive.google.com/file/d/1b9UfeqFvEu0t4sTGNd8yiJ1m60x...

Email: essence_mallard.5a@icloud.com

Hi, Kilian here :) ML engineer / research-minded generalist with a recent M.Sc. in Informatics from TUM, including a thesis on machine unlearning in medical imaging (@Harvard Medical School). I’ve worked on problems like reinforcement learning for tumor landmark detection in MRI, and deep learning for physical systems and protein structure prediction.

I like forming own ideas and following them through — from literature review to implementation, evaluation, and iteration. I can reproduce papers, fine-tune models, explore new methods, and design experiments that actually test hypotheses. I’m especially motivated by early-stage work that blends research thinking with practical engineering.

In team settings, I tend to gravitate toward coordination and planning roles, and outside of work, I’ve led a 300+ member volleyball department for several years — which taught me how to manage people, not just models.

I'm looking for roles at the intersection of research and engineering, eg early-stage AI projects where curiosity, ownership, technical depth matter and impact-driven development are valued.

kla-s commented on OpenAI releases image generation in the API   openai.com/index/image-ge... · Posted by u/themanmaran
matheusmoreira · 4 months ago
Reality is turning into some kind of Hideo Kojima game.

https://youtu.be/-gGLvg0n-uY

kla-s · 4 months ago
Wow that video is awesome, thanks for sharing

Deleted Comment

kla-s commented on Coffee reduces risk of Type 2 Diabetes; okay to add cream, but not sweetener   ajcn.nutrition.org/articl... · Posted by u/hilux
kacesensitive · 6 months ago
Breaking: sugar causes diabetes
kla-s · 6 months ago
To add some nuance, unused/unnecessary sugar will cause diabetes. If you are in high cardiovascular load consuming more than you can take in as eg with long distance triathlon, to my knowledge you will not increase your diabetes risk. It's more a matching supply and demand thing.
kla-s commented on Cognitive Behaviors That Enable Self-Improving Reasoners   arxiv.org/abs/2503.01307... · Posted by u/delifue
idiotsecant · 6 months ago
I sometimes see these reddit threads of people talking about the experience of having an internal monologue. I have no such monologue, at least not one that is accessible to the part of my mind that calls itself 'me', but I have often wondered if that monologue is something like a 'chain of thought'. I feel like maybe without access to that 'idea feed' maybe my planning and executive functioning is less effective than some other people. I do find myself quite more effective with those sort of tasks when I do a little 'chain of thought' notepad.

I also suspect I spend less time ruminating and second-guessing myself and other anxious behaviours that I imagine would come with having someone talking in your ear all day, but that's probably off topic.

kla-s · 6 months ago
Genuine question, how does multi step reasoning work for you then? Like eg if you have some math problem that's trivially to solve individually but needs multiple steps, lets say 16 * 3 + 5? How does 16 * 3 = 48 land in some 'register' of your brain (short term memory), so that you can then add 5 to get to 53? Maybe 16 * 3 + 5 is to easy for you and you'll just 'see' it but the question still stands, just choose a more complex problem.

Isn't the same meta process at play when thinking about more fuzzy topics?

kla-s commented on MIT 6.S184: Introduction to Flow Matching and Diffusion Models   diffusion.csail.mit.edu... · Posted by u/__rito__
__rito__ · 6 months ago
Our MIT class “6.S184: Introduction to Flow Matching and Diffusion Models” is now available on YouTube!

We teach state-of-the-art generative AI algorithms for images, videos, proteins, etc. together with the mathematical tools to understand them.

Flow and diffusion models are mathematically demanding subjects - which is why many lectures restrict themselves to teaching high level intuition. Here, we give a mathematically rigorous and self-contained introduction yet aimed at beginners in AI. We hope you will like it!

From: https://x.com/peholderrieth

kla-s · 6 months ago
Thank you, for making the effort of making this so accessible! Danke :)
kla-s commented on Zelensky leaves White House after angry meeting   bbc.com/news/live/c625ex2... · Posted by u/yakkomajuri
afavour · 6 months ago
Fair, I've updated my post. I'd argue it's not just FPTP presidential systems, though. Even in proportional representation you still only get one vote so you pick the candidate that's the best fit for you, you still don't get to pick and choose which parts of their agenda get enacted.
kla-s · 6 months ago
Well then thats „Volksabstimmungen“ as Switzerland has it for you.

u/kla-s

KarmaCake day39November 4, 2022
About
Currently looking for a job with interesting and impactful ml problems to solve. Interested in large action models for robotics/ interaction with reality. One dream of mine is to build a flight controller for an IMOCA which indirectly controls pitch -> ride height, while the rules allow no elevator.

essence_mallard.5a@icloud.com

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