For Mac users, ffWorks [1] is an amazing frontend for FFmpeg that surfaces most of the features but with a decent GUI. It’s batchable and you can setup presets too. It’s one of my favorite apps and the developer is very responsive.

Handbrake and Losslssscut are great too. But in addition to donating to FFmpeg, I pay for ffWorks because it really does offer a lot of value to me. I don’t think there is anything close to its polish on other platforms, unfortunately.

[1]: https://www.ffworks.net/index.html