What made you suspect it? What symptoms did you have?
Irregular bowel movements, cramps that I couldn't attribute to what I ate, inexplicable fatigue. Eventually it was a bright red blood in stool which made me force my doctor to take it seriously.
Readit Newsdev_throw commented on Cancer rates are rising in young people scientificamerican.com/ar... · Posted by u/Brajeshwar
dev_throw commented on Cancer rates are rising in young people scientificamerican.com/ar... · Posted by u/Brajeshwar
36 y/o male with stage 4 colon cancer. Diagnosed in 2016. Lifelong triathlete / healthy eater. I think it's easy to write this off and just better screening, but I think that's certainly a necessary, but not sufficient explanation.
I'm open to other ideas, but I have to imagine some of this is due to changes in our environment and food supply. plastics everywhere, pesticides in our food, pollution in the air.
Stage 4 as well, diagnosed in 2021. Lifelong vegetarian, mostly ate organic foods and generally active. I always suspected something was wrong with my gut, but didn't think it would be cancer. No genetic component either.
dev_throw commented on Ask HN: Enough is enough. What can we do about Xfinity (Comcast)? · Posted by u/dev_throw
For your immediate issue, if you're getting charged for services you did not order and Comcast won't make it right, take them to small claims court. You don't need a lawyer to do this. The odds are very good that Comcast will make it right when they're notified of the lawsuit. If they don't, they'll probably not show up and you'll get a default judgement.
For the larger issue, I don't know. Since Comcast is the only real option where I live, I've been wrestling with this question for years.
Thanks, I am intimidated by the process of court but I'll look into it. Will they be notified automatically, or do I have to serve them the notice?
It is insane that we tolerate this in 2023. I actively switch to other providers even if speeds are lower, but it is impossible to avoid their monopoly. Short of lobbying for municipal broadband, I am at a loss as well.
dev_throw commented on Ask HN: Enough is enough. What can we do about Xfinity (Comcast)? · Posted by u/dev_throw
Accidentally submitted it without a description so I'll just put it here.
Xfinity (Comcast) support is non-existent and actively lies to me about promotions or what I will be billed. Every time I call them to dispute, they waste an hour of my time and either throw me a $10 credit that I'm not sure is even getting applied. Different departments don't know about what the other is doing.
I'm now getting charged $70 for international calls I did not make.
How can I escalate these issues? Can I just cancel all association with them cleanly by reporting them to my credit card company? They seem ok with atrocious service because of their monopoly. Why do we put up with this blight?
dev_throw commented on Anti-tumor activity of all-trans retinoic acid in gastric-cancer pubmed.ncbi.nlm.nih.gov/3... · Posted by u/birriel
The maintenance was pretty easy tbh. 5FU for 15 minutes (bollus) once a week.
Great point about tumor dna. It does change and the “usual” treatments become less effective. That’s when the experimental drugs are usually brought in to the treatment plan.
I am living a pretty normal life for 4 of 7 days. And honestly I’m grateful it’s only 3 days that I’m less productive or just kind of tired/ spaced out.
Another PSA- start your start up before health gets in the way. Health really is wealth and having time with energy and a clear mind is in shorter supply once health issues arise. But also balance work and life. Ok no more PSAs today :)
Health really is the only wealth, amen to that. Ah, my 5FU was a 2 day pump affair that left me in a totally nauseous haze; I do not miss that at all. 4 out of 7 days is great.
I hope you are able to get to even more tolerable therapies in the future!
dev_throw commented on Anti-tumor activity of all-trans retinoic acid in gastric-cancer pubmed.ncbi.nlm.nih.gov/3... · Posted by u/birriel
Small PSA:
I’ve got stage 4 colon cancer- I see these sorts of articles passed to me from family members.
While encouraging that these discoveries are being made it’s not necessarily something that you can take to the doctor and get started with. The following needs to happen:
1- it applies to your cancer/genetics/geneticdefects 2- it’s in a stage that you can be part of testing in human trials which means usually a specialist cancer hospital. (As a side note I recommend MD Anderson as a treatment hospital. They treat me very well and advocate well with insurance fights. And if you have cancer, live in the US you will fight with you insurer) 3- Is it even ready?? Usually no. It’s just the first paper written about it and others need to reproduce the results. Then about 10 other lucky miracles happen and human trials can start. 4- don’t be afraid to go back and forth with your doctor.
I’m currently doing maintenance chemotherapy but some areas flared up and they wanted to add another chemo drug. There were 2 options and we discussed and went with the option I tolerated better.
I do HIGHLY recommend that you establish a rapport with your doctor so that you can discuss treatment options freely. The way it works at MDACC and I’m sure very similar to other cancer hospitals. Is they do all the typing and dna sequences up front. It helps them diagnose the cancer and prognosis etc. and then that lives in your chart. Typical treatment is to use traditional known chemo treatments and if they are not effective they start adding the trials that match your dna/cancer type.
Very long winded way to say unless someone in your life asks you to send these sorts of things it’s kind of like getting a lottery ticket for 10 years from now.
Stage IV CRC as well. Agreed, for the vast majority, it is still cytotoxic chemotherapy. I used to follow these innovations hoping to bring it up with my onc, but rarely do any of them work better than standard of care in vivo.
I hope you're handling maintenance chemo okay. Tumor DNA can change over time, so get a biopsy at some point to see if you qualify for other treatments.
dev_throw commented on I’m not a programmer, and I used AI to build my first bot blog.replit.com/building-... · Posted by u/todsacerdoti
All good until we get a new vector of subtly poisoned training data introducing vulnerabilities if one doesn't understand the generated code.
dev_throw commented on ROCm is AMD's priority, executive says eetimes.com/rocm-is-amds-... · Posted by u/mindcrime
Now if only they would offer some bigger Arc GPUs...
I would have picked up a 32GB+ Arc over my 3090 in a heartbeat. Maybe even a 24GB card.
16 GB is a really nice offering at that price point for AI workloads. I'm keeping my fingers crossed for a higher end Battlemage offering and some real competition for Nvidia.
dev_throw commented on ROCm is AMD's priority, executive says eetimes.com/rocm-is-amds-... · Posted by u/mindcrime
It's absolutely mindboggling to me that AMD is still struggling so badly on this.
There is an absolutely enormous market for AMD GPUs for this, but they seem to be completely stuck on how to build a developer ecosystem.
Why aren't AMD throwing as many developers as possible submitting PRs for the open source LLM effort adding ROCm support, for example?
It would give AMD real world insights to the problems with their drivers and SDKs as well, which are incredibly numerous.
People would be willing to overlook a huge amount of jank for cheap(er) cards with large VRAM configurations. I don't think they when need to be particularly fast, just have the VRAM needed, which I'm sure AMD could put specialist cards together for.
Intel has managed to get their drivers on 23.04 Ubuntu with no additional packages needed to be installed for their Arc dGPU offerings.