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dashmeet commented on On doing hard things   parv.bearblog.dev/kayakin... · Posted by u/speckx
dashmeet · 5 months ago
> But I think there’s a quiet dignity in the almost [success] stories too.

The last line hit hard. Need to remind myself of this sometimes

dashmeet commented on Ask HN: How do you monetize personal code if it's not an "app"?    · Posted by u/splimeproject
Uzmanali · 9 months ago
I created a niche CLI tool to clean messy CSVs. It was too small for a startup, so I made a simple landing page. Then, I shared it in forums and added a 'buy me a coffee' link. To my surprise, it brought in small but steady income. You can also bundle tools into a digital product (like a 'developer toolkit') and sell on Gumroad. APIs and microservices on RapidAPI or GitHub Sponsors also work if your tool solves a real pain point.
dashmeet · 9 months ago
What’s the link to the csv tool?
dashmeet commented on Scientists crack how aspirin might stop cancers from spreading   bbc.com/news/articles/c1d... · Posted by u/SirLJ
achillesheels · 10 months ago
So is here any positive correlation with cancer survivor rates with those with low to extremely low platelets? Excluding blood cancers of course .
dashmeet · 10 months ago
This is actually a VERY good question that should be further investigated. I hope the researchers are already looking into this, but adding it my list of things to bug medical professionals about just in case
dashmeet commented on OpenAI Deal Lets Employees Sell Shares at $86B Valuation   bloomberg.com/news/articl... · Posted by u/upmind
dchftcs · 2 years ago
The catch is that there are >10 startups and big-tech teams trying to do what OpenAIs is doing, and at least a few of them appear to be competitive. One or two of them may emerge as a winner. But there's only one Nvidia.

With that said, I do believe Nvidia is overvalued - if it triples profit its PE ratio would still be 30 (i.e. 30 years to return on investment), while there's a fairly good chance someone would catch up to them in 10-20 years.

dashmeet · 2 years ago
I’m pretty sure you’re looking at trailing PE. If you look at forward PE it’s only about 35. If you tripled profit, we’d be looking at about 12.

Using trailing PE shows an inaccurate picture for a high growth company so it makes more sense to just take the last quarter and project forwards.

dashmeet commented on Tesla Q4 2023 Earnings Report [pdf]   digitalassets.tesla.com/t... · Posted by u/mfiguiere
jliptzin · 2 years ago
Was that true in 2023? Don’t know just what my friend told me when he bought his model 3 a few months ago. He decided to pull the trigger on it because it was the same price as a brand new camry
dashmeet · 2 years ago
Not true in 2023. In 2023 every version of the model 3 qualifies for the 7500 tax credit in the US
dashmeet commented on Flu deaths in the US (2017-2023) per week   old.reddit.com/r/dataisbe... · Posted by u/belltaco
theodorejb · 2 years ago
What happened to the flu in 2020 and 2021?
dashmeet · 2 years ago
Isolation during corona/covid prevented the transmission of disease.
dashmeet commented on Malignant melanoma deploys elegant molecular mechanism to evade immune responses   cancer.columbia.edu/news/... · Posted by u/geox
smadge · 2 years ago
How do cancers have sophisticated mechanisms for evading immune responses when they don’t have any adaptive pressure? The cancer dies with the victim. It seems like the equivalent of mashing on the keyboard and getting a valid program.
dashmeet · 2 years ago
They do have adaptive pressure. 100s of millions of years of single cell evolutionary instincts live within our cells and the desire to survive. Being a multicellular organism is a relatively new learned behavior, and a human cell returning to that old mindset is basically cancer.

The only problem is that these individually minded (cancer) cells have every ability of your healthy cells and have basically stopped caring about the greater whole and care about themselves. Then they evolve at a micro level for their survival to fend off chemo, immune system, radiation etc. All it takes is one adapted/surviving cell to come back strong.

The sophisticated mechanisms for evasion exist because they have all the methods of evading your immune system that healthy multicellular organisms need to function and they multiply and increase their mutation rate to try new methods to survive and thrive.

I view cancer cells as single cells to understand their behavior with the adaptations of all the healthy cells returning to their “baser instincts”.

Source: Caretaker of a cancer patient and former cell bio major

PS: Take all the above with a grain of salt

Fuck Cancer

dashmeet commented on I am dying of squamous cell carcinoma, and potential treatments are out of reach   jakeseliger.com/2023/07/2... · Posted by u/theoldlove
YZF · 2 years ago
Money and politics. Why can someone drive for 6 months in a country with a foreign driver's license but can't get a local license?

I've had this misdiagnosed medical condition for 25 years by multiple doctors. Nothing serious but extremely annoying. There are approved drugs in Europe for decades which are much better than the ones approved in North America. One day the company making the drug that's approved in North America decided to stop making it! You just could not get it. This was the event that finally led to the correct diagnosis for my condition because I was in so much pain I got to see the expert. Turns out my condition has a very simple non-prescription solution and for 25 years I've been taking the wrong meds that happen to alleviate this different condition as well!

So I am good but this condition is not uncommon. What are all the other people that really need this drug in North America doing?

I'm not sure what's the takeaway here. Maybe that efficient/smart organizations generally don't exist. This is just a reflection of human nature.

dashmeet · 2 years ago
If you're okay with it, could you expand/name the condition you thought you had, the actual one, and the medication(s)? Never know, might help someone else out
dashmeet commented on Ask HN: Self-employed people, what are you using for accounting software?    · Posted by u/johntiger1
dashmeet · 3 years ago
Wave http://waveapps.com/ Also use it to process payments

I also have it linked to my mercury business account. Trying to find another free business checking account that works with zelle but this will do for now

dashmeet commented on Exciting SQLite Improvements Since 2020   blog.airsequel.com/exciti... · Posted by u/thunderbong
OliverJones · 3 years ago
The clustered primary key (NO ROWID) setup that came in with SQLite version 3.8.2 (2013-12-06) makes it very fast indeed when used for a large persistent key-value store.

And later improvements have just continue to accrue.

This from a guy who just implemented a persistent object cache with it, and was blown away by how well it works. And my requirement was all SQLite versions 3.7 and later, so there's conditional code. (ROWID or not, UPSERT or not).

Not to mention there are probably ten or more of these databases in your mobile phone. We haven't heard, at least I haven't, about any monstrous day-1 vulnerabilities in this code.

A really good design choice, SQLite is, if your application can live with its local file system requirement.

dashmeet · 3 years ago
I wonder how this compares to using redis for key value caching purposes?

Definitely reduces the need for another dependency if that’s your thing and it fits your needs

u/dashmeet

KarmaCake day56May 5, 2016
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