How about, the reader is old and computer illiterate. Being drunk is not needed. For example, here on this site, there is this unused space left and right. I meanwhile scale all websites with such unused space, using Ctrl+`+` to get the font bigger without losing functionality. But this site has an attribute `width=75%` in the outermost table #main, which makes this unused space stay there. So scaling up the font using the mentioned key combination is losing functionality (= less space). Luckily I can tweak that here using a user CSS (`#hnmain {width: revert;}`) but an old computer illiterate will probably have a slight problem. So, don't make your users drunk, just ensure they are, like, 80 and do not have advanced computer skills.
Not quite 80, but the same premise http://theuserismymom.com/
There is also so much more to designing for low tech literate than spacing. The accessibility guidelines focus so much on UI and being able to see what is there, but don’t focus enough on understanding what can be done with the website/app. Making sure your buttons actually look like buttons is a decent start but knowing that you can press a button, what it will do as the action, and being able to undo it and go back are so so valuable to helping them learn how to engage with sites.
https://csszengarden.com/