aznumeric (u/aznumeric)

aznumeric commented on 1910: The year the modern world lost its mind derekthompson.org/p/1910-... · Posted by u/purgator

gattilorenz · 16 days ago

WW1 started (among other things) because the "superpowers" in Europe had been arming each other for quite a while in fear of aggression from the other superpowers (not completely unreasonable, given the wars of the previous century). This, in turn, forced the other superpowers to invest more in armaments and army. To top it off, they made treaties of alliance/military intervention (the Triple Alliance and the Triple Entente).

The assassination of the archduke was like flipping a light switch in a house saturated with gas. Austria declares war to Serbia, which is defended by Russia, so Germany has to declare war to Russia; Germany expects France to join Russia so they declare war to France, but their battle plans to conquer France require passing through Belgium. The UK needs Belgium to remain neutral, so they declare war to Germany... and so on. Once the wheels are in motion, and everyone is ready for war, war just happens - whether coke is there or not.

aznumeric · 16 days ago

Kinda like today. Europe is rearming in response to perceived risks from Russia. Then the “when you have a hammer…” effect: once capabilities exist, actors start seeing situations where using them seems rational—procurement begets posture, posture begets use-cases.

aznumeric commented on Military grade sonic weapon is used against protesters in Serbia twitter.com/nexta_tv/stat... · Posted by u/aquir

aznumeric · 5 months ago

Another video, from a different angle:

https://www.reddit.com/r/serbia/comments/1jchks6/novi_snimci...

Please take into account that this occurred during the fifteen-minute silence observed by the protesters in memory of the fifteen victims of the accident, which the protesters blame on the government corruption and which was the very reason for the start of the protests.

aznumeric commented on Subsonic Weapon used on the crowd in Belgrade today old.reddit.com/r/PrepperI... · Posted by u/justinzollars

aznumeric · 5 months ago

Another video, from a different angle:

https://www.reddit.com/r/serbia/comments/1jchks6/novi_snimci...

aznumeric commented on TSMC execs allegedly dismissed OpenAI CEO Sam Altman as 'podcasting bro' tomshardware.com/tech-ind... · Posted by u/WithinReason

JanSt · a year ago

Using Claude 3.5 Sonnet in Cursor Composer already shows huge benefits for coding. I'm more productive than ever before. The models are still getting better and better. I'm not saying AGI is right around the corner or that we will reach it, but the benefits are undeniable. o1 added test-time compute. No need to be snarky.

aznumeric · a year ago

If you like Cursor, you should definitely check out ClaudeDev (https://github.com/saoudrizwan/claude-dev) It's been a hit in the Ai dev community and I've noticed many folks prefer it over Cursor. It's free and open-source. You use your API credits instead of subscription and it supports other LLMs like DeepSeek too.

aznumeric commented on Ask HN: Good Sites for/with AI Enthusiasts? · Posted by u/wruza

aznumeric · a year ago

https://www.reddit.com/r/LocalLLaMA

https://www.reddit.com/r/singularity

https://paperswithcode.com

https://www.reddit.com/r/StableDiffusion

https://www.reddit.com/r/ClaudeAI

aznumeric commented on Show HN: AnythingLLM – Open-Source, All-in-One Desktop AI Assistant github.com/Mintplex-Labs/... · Posted by u/tcarambat1010

egamirorrim · a year ago

I've got an open ai API key, and I pay for chatgpt. I'd imagine switching to this and using openai would end up costing quite a lot? How are people running it relatively cheaply?

aznumeric · a year ago

One way people keep costs down when using OpenAI with an offline RAG system is by limiting the number of text snippets sent to the API. Instead of sending the whole database, they'll typically retrieve only the top 10 (or so) most relevant snippets from the vector database and just send those to OpenAI for processing. This significantly reduces the amount of data being processed and billed by OpenAI.

aznumeric commented on Some doctors moving away from ventilators for virus patients apnews.com/8ccd325c2be9bf... · Posted by u/onetimemanytime

podgaj · 5 years ago

I think it may matter more if you are zinc deficient when you are infected.

But Zinc does not need to be in the cell to help. It will also increase ACE2 activity, which is more important they are finding. When the ACE2 is destroyed, there is a build up of ANGII, which seems to be causing a majority of the issues. They are in a trial giving ACE2 directly to patients.

aznumeric · 5 years ago

I was under the impression that meat eaters generally aren't deficient in Zinc. What do you think ?

aznumeric commented on Some doctors moving away from ventilators for virus patients apnews.com/8ccd325c2be9bf... · Posted by u/onetimemanytime

podgaj · 5 years ago

I do not think I will be here long. It is even worse than it has been in academia.

I will share this with you, I do not think hydroxychloroquine is needed, only high dose zinc. It is looking more like lower ACE2 activity is causing the majority of issues. Since ACE2 needs zinc as a cofactor, well...

https://www.radboudumc.nl/en/nieuws/2020/radboudumc-research...

"Covid-19 enters the lungs via the ACE2 receptor. The virus binds to the receptor, which then pulls it into the lung cell where the virus can multiply. In case of a massive infection, this process makes the ACE2 receptors disappear from the outside of the cell. With that, their function also disappears."

aznumeric · 5 years ago

Can you share what's a high dose in this case, how many milligrams of zinc per day ? Also, with zinc it's important to increase the dose slowly or there might be some adverse effects, like hair loss.

aznumeric commented on Nitric oxide inhibits the replication cycle of SARS coronavirus (2004) jvi.asm.org/content/79/3/... · Posted by u/ajaviaad

podgaj · 5 years ago

So nutritionally we should be looking at things needed to stimulate the NOS gene (NOS1, NOS2, NOS3):

NOS2 cofactors are; Heme, FAD, FMN, and BH4

Zinc - It helps make BH4 through the GCH1 and PTS enzymes from GTP.

Riboflavin - it is the precursor for FMN and FAD. Notably zinc is needed to turn riboflavin into FMD and FAD.

B6 (P5P) - Needed for Heme synthesis.

Beets - The nitrates are turned into NO in the gut.

Black Tea - Shown to increase NO. And shown to inhibit SARS: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1142193/

Vitamin C - Helps protect BH4

But it is for certain another reason to examine zinc in health outcomes from SARS infection. The metal binding site of NOS is zinc also so...

aznumeric · 5 years ago

L-Arginine