"The question of what this would do in the human body, which is full of polymers with very sensitively evolved mechanical properties, was obvious - yet it was not asked in a funded capacity until we had been letting it accumulate in our kids for decades"
which the article I linked supports, people come out of the woodwork to argue we need "more evidence/an exact biochemical pathway" when we dont have the understanding/technology to actually do that.
HN is supposed to be a forum of educated, rational people capable of critical thought. Here are some basic facts.
1. Plastic is often presented in the media as some kind of monolithic hazardous compound where it is not. There are different kinds of plastic. Alternatives are usually economically and environmentally inferior.
2. The most common types of plastic for consumer applications are polyethylene and polypropylene, followed by polyvinyl chloride and polystyrene. PE and PP are biologically and chemically inert. The same reason why they don't break down is the reason why they are harmless. Polystyrene derived from a naturally occuring compound styrene found in some plants and can and does breakdown under attack of UV light, acids, microorganisms. All three PE, PP, and PS are most commonly manufactured without harmful additives. Only PVC uses significant quantities of plasticizers some of which are harmful. Unless you are chewing on your shower curtain you have little to worry about.
3. At least several hundred billion tons of commodity plastics have been mass produced over the last 70 years with little to no quantified, attributable environmental damage from these plastics. Most microplastic is essentially inert dust that is no different from other organic or inorganic dust such as pollen or clay. Plastics are not allergens because they are non reactive and do not stimulate an immune response. It is very likely that blood of animals contains plastic molecules along with thousands of other molecules in trace quantities doing no more harm than natural silt in a river system.
4.The fact that commodity plastics do not readily rot or degrade is a good thing. Petroleum carbon made into stable plastic and buried in a landfill is kept out of the atmosphere.
5. Plastic items are less energy demanding to recycle and produce in the first place because of lower thermal processing requirements than glass, metal or wood.
6. Lignin in wood is a natural plastic.
7. Most of the macro plastics in the ocean comes from Asia and the fishing industry. In the west it is buried in a landfill where it helpfully sequesters carbon.
8. Plastic items are often lighter to ship also consuming less energy that way versus alternatives.
9. Most microplastics in the ocean are from synthetic fibers and tire abrasion. I have yet to see a non handwaving study that these actually result in significant environmental harm. Maybe we should research more durable tire materials. Perversely electric vehicles wear tires quicker than ICE vehicles due to a more aggressive torque curve. Cotton has to be planted (diesel tractor), sprayed with fertilizers and pesticides, picked (diesel), spun, woven, etc. just because it's natural doesn't mean it's better for the environment at mass scale. This true of other things too like glass, metal, paper, etc.
10. People should stop irresponsibly hating on plastics when the alternatives are worse.
This neo Luddite Puritanism is just dumb and unscientific.
I challenge anyone to rebut my assertions with hard facts that quantify to supposed damage plastic does versus what alternatives would do.
You're missing a couple points yourself. For example, the article is talking about phthalates. These are additives added to plastics. These leech from microplastics. So your rant about how plastics are inert shows you didnt even understand the article yourself tbh.
There is plenty of evidence that these compounds are harmful and affect the biology. See the section on wikipedia on phthalates. What there isnt is much evidence and experimentation showing theyre NOT harmful.