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Kalanos commented on The "confident idiot" problem: Why AI needs hard rules, not vibe checks   steerlabs.substack.com/p/... · Posted by u/steer_dev
Kalanos · 12 days ago
Please refer to this as GenAI

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Kalanos commented on Ask HN: I underestimated how lonely building solo can be    · Posted by u/paulwilsonn
RomanPushkin · a month ago
I'm also building solo, applied to YC winter batch as solo, and I've been building solo for quite a while now.

My solo projects were on HN news multiple times getting hundreds and even 1000+ points (submitted by other folks tho). I am still building.

I didn't realize there is so many folks from HN building solo, so I literally 2 mins ago created a discord for all of us so we won't get lost after this post goes down: https://discord.gg/GaCz3qMK

Kalanos · a month ago
Good idea. Previously, I joined a python slack community and it helped a lot
Kalanos commented on PSF has withdrawn $1.5M proposal to US Government grant program   pyfound.blogspot.com/2025... · Posted by u/lumpa
Kalanos · 2 months ago
pypi put out a survey a while back that was full of bs questions about dei fluff. the lack of subject matter made me really question the competence of the project staff.
Kalanos commented on The allure of new languages vs. the necessity of problem-solving   dayvster.com/blog/are-we-... · Posted by u/ibobev
Kalanos · 3 months ago
Yes! Why is every company hiring for LLM talent? Companies that have no business doing so. They probably don't even know that supervised machine learning exists.
Kalanos commented on Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out   gavi.org/vaccineswork/den... · Posted by u/slu
Kalanos · 3 months ago
In the US, there is no male test for HPV
Kalanos commented on 'Click-to-cancel' rule is blocked   apnews.com/article/ftc-cl... · Posted by u/gok
Kalanos · 5 months ago
"FTC made a procedural error by failing to come up with a preliminary regulatory analysis, which is required"
Kalanos commented on AlphaGenome: AI for better understanding the genome   deepmind.google/discover/... · Posted by u/i_love_limes
Kalanos · 6 months ago
The functional predictions related to "non-coding" variants are big here. Non-coding regions, referred to as the dark genome, produce regulatory non-coding RNA's that determine the level of gene expression in a given cell type. There are more regulatory RNA's than there are genes. Something like 75% of expression by volume is ncRNA.

u/Kalanos

KarmaCake day402July 26, 2021View Original