Please refer to this as GenAI
Readit NewsKalanos commented on The "confident idiot" problem: Why AI needs hard rules, not vibe checks steerlabs.substack.com/p/... · Posted by u/steer_dev
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Kalanos commented on Ask HN: I underestimated how lonely building solo can be · Posted by u/paulwilsonn
I'm also building solo, applied to YC winter batch as solo, and I've been building solo for quite a while now.
My solo projects were on HN news multiple times getting hundreds and even 1000+ points (submitted by other folks tho). I am still building.
I didn't realize there is so many folks from HN building solo, so I literally 2 mins ago created a discord for all of us so we won't get lost after this post goes down: https://discord.gg/GaCz3qMK
Good idea. Previously, I joined a python slack community and it helped a lot
Kalanos commented on PSF has withdrawn $1.5M proposal to US Government grant program pyfound.blogspot.com/2025... · Posted by u/lumpa
pypi put out a survey a while back that was full of bs questions about dei fluff. the lack of subject matter made me really question the competence of the project staff.
Kalanos commented on The allure of new languages vs. the necessity of problem-solving dayvster.com/blog/are-we-... · Posted by u/ibobev
Yes! Why is every company hiring for LLM talent? Companies that have no business doing so. They probably don't even know that supervised machine learning exists.
In the US, there is no male test for HPV
Kalanos commented on 'Click-to-cancel' rule is blocked apnews.com/article/ftc-cl... · Posted by u/gok
"FTC made a procedural error by failing to come up with a preliminary regulatory analysis, which is required"
Kalanos commented on AlphaGenome: AI for better understanding the genome deepmind.google/discover/... · Posted by u/i_love_limes
The functional predictions related to "non-coding" variants are big here. Non-coding regions, referred to as the dark genome, produce regulatory non-coding RNA's that determine the level of gene expression in a given cell type. There are more regulatory RNA's than there are genes. Something like 75% of expression by volume is ncRNA.