Probably not at the top of everyones mind, but this will be great for gamers in SA. Lots of games-as-a-service (i.e. no dedicated server software you can run yourself) are hosted on AWS. Overwatch is a particular example that might now receive African servers off of this.
It doesn't necessarily mean the GaaSs (and equally PaaSs) will utilize the new region, there's a couple reasons, sometimes dependent services are rolled out slowly elsewhere - e.g. bigquery, cloud/pub, even their end user Workmail has limited regions, in addition sometimes the egress network and compute charges could be a multiple of us-east/west making the offering prohibitively expensive, and then it depends on the local connectivity itself, if major eyeball / gamer ISPs won't peer initially it might just be as well hosting in nearest Europe region to avoid the double RTL - you see this effect in markets like Singapore with Singtel, Germany with DTAC, and to a degree US with Comcast when server providers pick up local transit from HE/cogent even NTT in some parts - when AWS opened Singapore it was universally terrible routing until they got aggressive about peering and remote peering in the region.
Good news nonetheless, early days though...