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realitsflat commented on In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)   nature.com/articles/d4158... · Posted by u/tayne
jamesblonde · 4 years ago
You don't apply DNA methylation - it is the basis for measuring epigenetic age. I mentioned HRT as one way of reducing epigenetic age for epithelial cells.
realitsflat · 4 years ago
Right, just wanted to clear up the concept.

The reference you gave measure blood or urine samples which would probably not be representative of epithelial cells. Also i like non-descriptive but professional looking stock photos of multi-pipettes and the ubiquitus vortex genie 2. Extra points for consecutive photos of the same tip-rack in obviously proffessional use.

realitsflat commented on Ask HN: What are the changes you made in your life and never look back?    · Posted by u/saadalem
realitsflat · 4 years ago
Went vegetarian ~13 years ago. No regrets, no problems, no complaints.
realitsflat commented on In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)   nature.com/articles/d4158... · Posted by u/tayne
jamesblonde · 4 years ago
Epigenetics is fascinating. I just came back from a project meeting, where i work with people who discovered that HRT (hormone replacement therapy) slows down epithelial cell aging. Epithelial cells are the cells that cover all your vital organs, so they are important for aging.

Now, there are even commercial companies that measure Epigenetic age of cells with a technique called DNA methylation.

References: https://investinaustria.at/en/news/2022/03/epigenetic-clock-...

https://www.mydnage.com/?gclid=Cj0KCQjwheyUBhD-ARIsAHJNM-Mrk...

realitsflat · 4 years ago
DNA methylation is not a technique that can be applied. It is a biological system present in your cells silencing expression of genes that are not useful for a cells current behavior. Differently differentiated cells have different "genes methylated" and thus inactivated which govern their behavior and potential for further sub-differentiation. Indiscriminately "reversing methylation" would probably lead to a lot of "cancering".
realitsflat commented on Telegram has released user data to German Feds in multiple cases   twitter.com/disclosetv/st... · Posted by u/CHEF-KOCH
realitsflat · 4 years ago
Does it not seem reasonable that if a chat group has, lets say, more than 1000 participants, whatever is said should be considered said in public?

u/realitsflat

KarmaCake day3June 4, 2022View Original