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handsomechad commented on Mysterious heart damage, not just lung troubles, befalling Covid-19 patients   khn.org/news/mysterious-h... · Posted by u/branko_d
koheripbal · 6 years ago
Covid-19 is a type of virus that does not mutate much at all. It has error correction in replication.

Across all the variants found globally so far, there have only been changes to 20 base pairs - most of which (possibly all) do absolutely nothing.

Your immunity will likely make any re-infection much much lighter - even many years from now.

Interestingly, Coronaviruses generally, can still re-infect you even after you've developed immunity (or been vaccinated) - albeit to a much lesser extent. It's one advantage they have over influenza, and why they can get away with error correction.

handsomechad · 6 years ago
can you, or someone who understands this, explain to the layperson what this means.

the last sentence in particular, what does reinfection have to do with error correction (what is error correction (assuming it has to do with the genome)?)

why is that an advantage over influenza?

handsomechad commented on How SEO Ruined the Internet   superhighway98.com/seo... · Posted by u/midef
durnygbur · 6 years ago
Google with default settings is useless and using more sophisticated queries quickly walls off the user with increasingly annoying captcha.

The "world's knowledge under you fingertips" motto is still valid and brilliant though. My personal solution is library of OCR-ed PDFs with most established books from various domains, git repository for each domain. Greppable in miliseconds, locally. Hijack this, SEO experts!

handsomechad · 6 years ago
do you have a link to this solution
handsomechad commented on Trump announces tariffs on all Mexico goods   bbc.co.uk/news/world-us-c... · Posted by u/benj111
handsomechad · 7 years ago
why was this flagged? i would be interested to hear the perspective of the HN userbase on this event / issue?
handsomechad commented on Assange Indicted Under Espionage Act, Raising First Amendment Issues   nytimes.com/2019/05/23/us... · Posted by u/tysone
mindslight · 7 years ago
The sad answer is that there are essentially only 3 sovereign countries left in the world. Legal reasoning only comes into play when making the justifications more plausible.
handsomechad · 7 years ago
what are the three you are thinking of?

USA

China

Russia

and their respective allies / blocs ?

handsomechad commented on America's loneliness epidemic: A systemic risk to organizations   smartbrief.com/original/2... · Posted by u/laurex
mjevans · 7 years ago
What is the inverse of loneliness? Belonging, a sense of community and companionship.

It is my perception that, at least in America and I suspect in many other places, competition pressure centered around places with strong "second place" (Job) opportunities combined with decades of civic mal-planning and treating symptoms (for some) rather than root causes (for all) have combined with a regressive tax/compensation structures to destroy the middle class and upward mobility.

There are not enough "first places" near jobs. The cost of those places and the demands of the jobs combine to sour the time, energy, and opportunity left for "third places" (#1). Areas and activities where idle time is spent when seeking connections to others. Those places, at least for me, also tend to have a high barrier to participation/entry and very poor discover-ability.

I theorize this might be related to the same issue described in another post, https://news.ycombinator.com/item?id=19902782 where "the old Internet" had many small venues, who's main reason for existence was not profit, but the benefit of their "members" (users). They were private, intimate, locations where fans of a given thing could gather and learn more about that thing and themselves; with small local histories that allowed for safer exploration.

A more stable place, where I had a real career I believed in, and a real home that I could start putting equity in to and around; a place where actual roots and structures and friends that would probably stay in the area also existed. That's what I feel we need to actually fight and win the battle against loneliness.

#1 https://en.wikipedia.org/wiki/Third_place

handsomechad · 7 years ago
"It is my perception that, at least in America and I suspect in many other places, competition pressure centered around places with strong "second place" (Job) opportunities combined with decades of civic mal-planning and treating symptoms (for some) rather than root causes (for all) have combined with a regressive tax/compensation structures to destroy the middle class and upward mobility. "

i literally cannot parse this sentence. i tried - i am a native english speaker but it's just confusing to me what the proposition being made here is. i tried reading it a few times.

it is late but if someone could clarify it would be much appreciated.

handsomechad commented on India will overtake the US economy by 2030   weforum.org/agenda/2019/0... · Posted by u/alphagrep12345
onetimemanytime · 7 years ago
OK, but can't China or India take x% of GDP and built their military with it? Go ahead and fight someone spending 2x as much as you
handsomechad · 7 years ago
why did this get downvoted, my first thought was exactly along these lines. does anyone have an answer?
handsomechad commented on Just a few drinks can change how memories are formed   news.brown.edu/articles/2... · Posted by u/Elof
handsomechad · 7 years ago
Ever since practicing mindfulness and become more aware of my emotional state, drinking alcohol has become a nonstarter for me. It took a while for me to truly connect the dots, but, following a night of imbibing, I crash really hard on not just a physiological level but an emotional, psychological level as well. In fact I find it hard to separate the two reactions. To me they are basically the same thing, overall increased levels of "pain" or "anxiety" or "neurosis" manifesting in my inner being, my soul if you will.

I know that sounds a bit woo woo but it's sort of an ineffable and inarticulable idea. I'm 100% sure I feel it though, every time I drink I sleep poorly, I'm much more irritable once the alcohol wears off the next afternoon, and by the time the evening comes around, assuming I don't re-dose, I'm much more prone to ruminate on negative thoughts or seek mindless stimulation to distract my mind from the general malaise.

I think alcohol really is a mainstream and socially acceptable means of anxiety self-medication. It's a deeply engrained cultural habit that has been around for millenia, and I don't expect or advocate for it to stop, but for me it has palpable deleterious effects on my whole being.

handsomechad commented on US Surgeon General Declares E-cigarette Epidemic Among Youth [pdf]   e-cigarettes.surgeongener... · Posted by u/Pulcinella
code_beers · 7 years ago
I agree. I am very dependent upon matcha green tea. If I don’t have at least two cups per day, I feel terrible. But when I do take it daily, it provides an incredible amount of clarity and energy. I’ve come to accept the downsides - and there are always downsides - because overall, it’s a net positive in my life. I don’t doubt there are people in similarly positive but dependent relationships with far harder substances.
handsomechad · 7 years ago
what brand / dose do you drink? looking to switch off coffee to something more benign

u/handsomechad

KarmaCake day131December 28, 2016View Original