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apathy commented on Face transplant recipient’s donor face now failing   latimes.com/world-nation/... · Posted by u/hsnewman
skosch · 6 years ago
Those are cancers caused by viruses, and it's the viruses getting transmitted.

On the other hand, clonal transmission refers to the cancer cells themselves leaving sick individual A, entering healthy individual B, and continuing to reproduce there.

apathy · 6 years ago
You could use transmissible preleukemia (eg CHIP in allo transplants) as an example if you wished.

Direct unassisted clonal transmission in humans seems likely but, as you noted, it hasn’t been documented to the extent that Tasmanian Devil facial tumors have.

Warts are a corner case. I’m not sure whether it’s been determined if some hosts end up increasing the fitness of the shed cells. If so, that’s quickly heading towards a globally transmitted precursor lesion.

apathy commented on Face transplant recipient’s donor face now failing   latimes.com/world-nation/... · Posted by u/hsnewman
mkl · 6 years ago
Humans almost certainly are vulnerable to contagious cancer (there are a few known in other species: https://en.wikipedia.org/wiki/Clonally_transmissible_cancer) . We just haven't acquired/discovered any yet.
apathy · 6 years ago
HTLV, EBV, HPV

you better believe we have! It’s just rare (thank goodness).

apathy commented on Woman treated by doctors after her blood turned blue   theguardian.com/us-news/2... · Posted by u/EndXA
AlexDragusin · 6 years ago
I find it interesting, in fact blood can turn green as well, without being an alien:

https://en.wikipedia.org/wiki/Sulfhemoglobinemia

> Sulfhemoglobinemia is a rare condition in which there is excess sulfhemoglobin (SulfHb) in the blood. The pigment is a greenish derivative of hemoglobin which cannot be converted back to normal, functional hemoglobin. It causes cyanosis even at low blood levels.

>It is a rare blood condition that occurs when a sulfur atom is incorporated into the hemoglobin molecule. When hydrogen sulfide (H2S) (or sulfide ions) and ferric ions combine in the blood, the blood is incapable of carrying oxygen.

apathy · 6 years ago
Indeed, this is why hydrogen sulfide is toxic in smallish doses
apathy commented on Nearly a quarter of U.S. rural hospitals are on the brink of closure – report   modernhealthcare.com/arti... · Posted by u/Ice_cream_suit
povertyworld · 6 years ago
If not a single Republican voted for it that means the bill is entirely the responsibility of the Democrats. It is a bill created and passed exclusively by Democrats. The Democrats passed a Republican plan without one Republican vote. The Democrats had a filibuster proof supermajority, and they decided to pass Mitt Romney's healthcare plan. But it's all the Republicans fault. Obama didn't even try for a public option like he had promised during the campaign.
apathy · 6 years ago
Independent. The 60th vote was an independent who endorsed John McCain in preference to Obama.

How can one person manage to be so consistently incorrect?

apathy commented on Nearly a quarter of U.S. rural hospitals are on the brink of closure – report   modernhealthcare.com/arti... · Posted by u/Ice_cream_suit
povertyworld · 6 years ago
It passed with not one vote from Republicans, so there was no need to compromise. Will your fake news post be downvoted? Of course not.
apathy · 6 years ago
Remind us who tanked the public option in the ACA?

Hint: he was Al Gore’s running mate a decade prior. And he was never a republican.

apathy commented on More Fires Now Burning in Angola, Congo Than Amazon   bloomberg.com/news/articl... · Posted by u/adventured
dredmorbius · 6 years ago
Yeah, that's pretty stunning. Sulfur Oxide emissions also.

Though if you hit up January and look at SO4 emissions over the US and Europe, they're pretty terrifying as well.

Spotting wildfires by PM2.5 emissions is a part-time hobby, as is looking at MSLP and watching cyclonic storms developing. It looks as if the Atlantic hurricane season may start cooking off in the next week or so.

Not all channels have forecast values, but temps, winds, pressures, and precip do, so you can roll out a few days to see what the models are projecting. I've followed (and anticipated) most of the big storms over the past few years. Some false starts (a lot of swirls never really develop), but it was painfully obvious that Harvy and Florence were going to be massive storms.

In the Pacific, the unrelenting assaults on the Philippines, Taiwan, Japan, and mainland China are impressive.

apathy · 6 years ago
China tends to buy light crude instead of light sweet crude, hence the oil and derived fuels have more sulfur than is typical for European or American vehicles, industry, etc.

This is something of a problem when a country with as many people as China and an economy as growth-oriented as China's is, uh, firing on all cylinders.

apathy commented on Hundreds of extreme self-citing scientists revealed in new database   nature.com/articles/d4158... · Posted by u/dmckeon
ravar · 6 years ago
My understanding is that eigenfactor rates journals, not individual papers, so if somehow you get low-quality (whatever you want that to mean) papers into nature it has no independent way to realize that your specific paper is low quality. Also eigenfactor is biased towards favoring larger journals, which is not obviously a good thing. It would honestly be really cool if someone did page rank for individual papers. It seems like a much saner metric than anything that is currently used.
apathy · 6 years ago
Oh good grief you’re right. This is doubly sad because using an ensemble metric for per-author eigenfactor seems like it would be tractable.

Carl Bergstrom is a smart guy so I suppose the practical implementation of the above must have some wrinkles, but with enough brute force it seems tractable. What I despise more than anything is the gaming that takes place for “impact factor”.

I do OK by standard metrics but would very much like to know where I stand by less easily gamed metrics of influence.

apathy commented on Hundreds of extreme self-citing scientists revealed in new database   nature.com/articles/d4158... · Posted by u/dmckeon
asimjalis · 6 years ago
PageRank might be better way to evaluate quality. It too can be gamed. Maybe not as easily, though.
apathy · 6 years ago
Aka eigenfactor
apathy commented on We shouldn’t take peer review as the ‘gold standard’   washingtonpost.com/outloo... · Posted by u/danso
tptacek · 6 years ago
Just to clarify: this article is against gold standards, not against peer review. It concludes by observing that peer review is a necessity. The argument it raises is that peer review doesn't mean what lay audiences think it means.

I think they're clearly correct, and that even on HN, in a community that (roughly) prides itself on being scientifically literate, there are broad misunderstandings of what peer review means (during the bogus "Sokal Squared" hoax, for instance, many commenters implied that peer review prior to publication was meant to encompass replication). Also, while I'm not a "scientist", I've gotten to do some peer review work for ACM and Usenix, and even in the little bit of review I did, I seen some shit. There is much less formality and oversight to review than you might expect.

apathy · 6 years ago
As a machine learning / probabilistic programming friend put it, (journal) peer review is boosting with three weak learners.

Better than nothing, but very far from ironclad. Only replication really verifies scientific findings. Everything else is just window dressing.

(I say this as a regular reviewer; for whatever reason, this particular week I’m reviewing for both Science and Nature.)

apathy commented on A Cold Take on IBM, Red Hat and Their Hybrid Cloud   platformonomics.com/2019/... · Posted by u/pinewurst
Merrill · 6 years ago
How did the author not quote the metaphor "tying two bricks together won't make them float"?
apathy · 6 years ago
Timeless wisdom.

u/apathy

KarmaCake day1638August 24, 2007
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