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allie1 commented on Gut bacteria from amphibians and reptiles achieve tumor elimination in mice   jaist.ac.jp/english/whats... · Posted by u/Xunxi
teekert · a day ago
It starts with mutations (sometimes accelerated by mutagens (smoke, alcohol, etc) or inflammation (viruses, infections, etc) or just chance (things like asbestos up the division rate by constant physical damage and thus up the probability or an error in copying).

But there is much more to it. This is a nice paper for an overview: Hallmarks of Cancer (tng) [0]. It (among others) adds the very important and for years underestimated role of the immune system to the original 2000 paper.

[0] https://www.cell.com/fulltext/S0092-8674(11)00127-9

allie1 · a day ago
Would sports also increase the rate of division? Bodybuilding for example you intentionally make micro tears in muscles to get them to repair and grow (lay person, apologies for the mistakes)
allie1 commented on Without data centers, GDP growth was 0.1% in the first half of 2025   fortune.com/2025/10/07/da... · Posted by u/ryan_j_naughton
usrnm · 2 months ago
GPUs aren't built in the US, though. I wonder, what percentage of all the stuff in a typical datacenter is actually made in the US
allie1 · 2 months ago
The margins collected by Nvidia end up in the US. And Nvidia and its employees get paid in the US. Only a small part of the revenue is outside the US.
allie1 commented on Without data centers, GDP growth was 0.1% in the first half of 2025   fortune.com/2025/10/07/da... · Posted by u/ryan_j_naughton
KronisLV · 2 months ago
I mean, most of my friends (especially the artists but also software devs) seem to hate AI with a passion: sometimes because of the ethical bankruptcy, other times because of the amount of slop it produces and how in your face it is due to the hype cycle, other times due to a belief that it more or less leads to brainrot and atrophy of cognitive abilities.
allie1 · 2 months ago
The slop is real. Especially when I see promoters of platforms for vibe coders. They don't understand the implications of lack of security in potentially viral apps. It's easy to consider them as WMDs.

People have the same password across services. They share personal information. In a geopolitical climate as today's, where the currency of war is disruption, it can wreak havoc.

allie1 commented on Ask HN: Cursor or Windsurf?    · Posted by u/skarat
danpalmer · 7 months ago
Zed. They've upped their game in the AI integration and so far it's the best one I've seen (external from work). Cursor and VSCode+Copilot always felt slow and janky, Zed is much less janky feels like pretty mature software, and I can just plug in my Gemini API key and use that for free/cheap instead of paying for the editor's own integration.
allie1 · 7 months ago
I just wish they'd release a debugger already. Once its done i'll be moving to them completely.
allie1 commented on What to Do   paulgraham.com/do.html... · Posted by u/npalli
tlogan · 9 months ago
I think the issue with saying “make good new things” is that things themselves aren’t inherently good or bad—they’re just things. It’s the person who makes them that can be good or bad.

I have a saying (among others from my dad) that captures a similar idea: “Make things, and be good.”

allie1 · 9 months ago
I think it’s good in the sense of things that are positively affecting others’ lives.
allie1 commented on FBI Raids Home of Polymarket CEO Shayne Coplan   axios.com/2024/11/13/poly... · Posted by u/jaboutboul
galleywest200 · a year ago
Accepting a presidential pardon requires an admission of guilt. Would being a confirmed criminal aide them in business in any way?
allie1 · a year ago
For a crypto based business for something that crypto enthusiasts wouldn't consider a crime, probably would help.
allie1 commented on     · Posted by u/allie1
allie1 · a year ago
This aged well! Thanks to https://news.ycombinator.com/user?id=Kye for digging it up
allie1 commented on OpenAI to become for-profit company   reuters.com/technology/ar... · Posted by u/jspann
tsimionescu · a year ago
Consistent here meaning, I guess, that all voting power will go to Sam Altman personally, right?
allie1 · a year ago
yeah, split with Microsoft.
allie1 commented on OpenAI to become for-profit company   reuters.com/technology/ar... · Posted by u/jspann
mtlmtlmtlmtl · a year ago
The most surprising thing to me in this is that the non-profit will still exist. Not sure what the point of it is anymore. Taken as a whole, OpenAI is now just a for-profit entity beholden to investors and Sam Altman as a shareholder. The non-profit is really just vestigial.

I guess technically it's supposed to play some role in making sure OpenAI "benefits humanity". But as we've seen multiple times, whenever that goal clashes with the interests of investors, the latter wins out.

allie1 · a year ago
We haven't even heard about who gets voting shares, and what voting power will be like. Based on their character, I expect them to remain consistent in this regard.

u/allie1

KarmaCake day642November 12, 2018View Original